Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Josef Ladenbauer"'
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
It is difficult to fit mechanistic, biophysically constrained circuit models to spike train data from in vivo extracellular recordings. Here the authors present analytical methods that enable efficient parameter estimation for integrate-and-fire circ
Externí odkaz:
https://doaj.org/article/85a037d778554f659901d36b5d3fc974
Autor:
Josef Ladenbauer, Klaus Obermayer
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 4, p e1006974 (2019)
Transcranial brain stimulation and evidence of ephaptic coupling have sparked strong interests in understanding the effects of weak electric fields on the dynamics of neuronal populations. While their influence on the subthreshold membrane voltage ca
Externí odkaz:
https://doaj.org/article/764dc92e8dcb4962b6e38b82cd9a19d0
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 6, p e1005545 (2017)
The spiking activity of single neurons can be well described by a nonlinear integrate-and-fire model that includes somatic adaptation. When exposed to fluctuating inputs sparsely coupled populations of these model neurons exhibit stochastic collectiv
Externí odkaz:
https://doaj.org/article/ae8c221041314dbf8cac940e827b3f43
Publikováno v:
Frontiers in Computational Neuroscience, Vol 11 (2017)
Noise correlations are a common feature of neural responses and have been observed in many cortical areas across different species. These correlations can influence information processing by enhancing or diminishing the quality of the neural code, bu
Externí odkaz:
https://doaj.org/article/6ea452e98ee142d986e12fa063973b06
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 11, p e1005206 (2016)
Transcranial brain stimulation and evidence of ephaptic coupling have recently sparked strong interests in understanding the effects of weak electric fields on the dynamics of brain networks and of coupled populations of neurons. The collective dynam
Externí odkaz:
https://doaj.org/article/3d34a403777e42788ac2b32f35f42ff7
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 4, p e1002478 (2012)
The ability of spiking neurons to synchronize their activity in a network depends on the response behavior of these neurons as quantified by the phase response curve (PRC) and on coupling properties. The PRC characterizes the effects of transient inp
Externí odkaz:
https://doaj.org/article/b1fddedfe76c4dafbfb1da44cb53e951
Publikováno v:
Sleep. 44
Study Objectives Aging is associated with detrimental changes in sleep physiology, a process accelerated in Alzheimer’s disease. Fine-tuned temporal interactions of non-rapid eye movement slow oscillations and spindles were shown to be particularly
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-12572-0⟩
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-12572-0⟩
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
The interpretation of neuronal spike train recordings often relies on abstract statistical models that allow for principled parameter estimation and model selection but provide only limited insights into underlying microcircuits. In contrast, mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc67fbfbfc8513cf18fb06dc7358ff8
https://hal.archives-ouvertes.fr/hal-02413914
https://hal.archives-ouvertes.fr/hal-02413914
Autor:
Agnes Flöel, Julia Ladenbauer, Josef Ladenbauer, Ulrike Grittner, Elena Avramova, Nadine Külzow, Rebecca de Boor
Publikováno v:
The Journal of Neuroscience. 37:7111-7124
Alzheimer's disease (AD) not only involves loss of memory functions, but also prominent deterioration of sleep physiology, which is already evident at the stage of mild cognitive impairment (MCI). Cortical slow oscillations (SO; 0.5-1 Hz) and thalamo
Multi-neuronal spike-train data recorded in vivo often exhibit rich dynamics as well as considerable variability across cells and repetitions of identical experimental conditions (trials). Efforts to characterize and predict the population dynamics a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9303e05aa3c8c882c0df29ed0ce141
https://doi.org/10.1101/671909
https://doi.org/10.1101/671909