Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Josef Houštěk"'
Autor:
Petra Janovska, Petr Zouhar, Kristina Bardova, Jakub Otahal, Marek Vrbacky, Tomas Mracek, Katerina Adamcova, Lucie Lenkova, Jiri Funda, Tomas Cajka, Zdenek Drahota, Sara Stanic, Arild C. Rustan, Olga Horakova, Josef Houstek, Martin Rossmeisl, Jan Kopecky
Publikováno v:
Molecular Metabolism, Vol 69, Iss , Pp 101683- (2023)
Objective: Non-shivering thermogenesis (NST) mediated by uncoupling protein 1 (UCP1) in brown adipose tissue (BAT) can be activated via the adrenergic system in response to cold or diet, contributing to both thermal and energy homeostasis. Other mech
Externí odkaz:
https://doaj.org/article/31f0b59f9117425794b61598c518ae9c
Autor:
Kristýna Čunátová, Marek Vrbacký, Guillermo Puertas-Frias, Lukáš Alán, Marie Vanišová, María José Saucedo-Rodríguez, Josef Houštěk, Erika Fernández-Vizarra, Jiří Neužil, Alena Pecinová, Petr Pecina, Tomáš Mráček
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110560- (2024)
Summary: Individual complexes of the mitochondrial oxidative phosphorylation system (OXPHOS) are not linked solely by their function; they also share dependencies at the maintenance/assembly level, where one complex depends on the presence of a diffe
Externí odkaz:
https://doaj.org/article/3d6dcc0d1f2e4e32bd0fb69463335c10
Autor:
Aleksandra Marković, Kateřina Tauchmannová, Miroslava Šimáková, Petr Mlejnek, Vilma Kaplanová, Petr Pecina, Alena Pecinová, František Papoušek, František Liška, Jan Šilhavý, Jana Mikešová, Jan Neckář, Josef Houštěk, Michal Pravenec, Tomáš Mráček
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 276 (2022)
Mutations of the TMEM70 gene disrupt the biogenesis of the ATP synthase and represent the most frequent cause of autosomal recessive encephalo-cardio-myopathy with neonatal onset. Patient tissues show isolated defects in the ATP synthase, leading to
Externí odkaz:
https://doaj.org/article/6d1f7f1ea1dc471ab1b1eaf632bb0f64
Autor:
Kristýna Čunátová, David Pajuelo Reguera, Marek Vrbacký, Erika Fernández-Vizarra, Shujing Ding, Ian M. Fearnley, Massimo Zeviani, Josef Houštěk, Tomáš Mráček, Petr Pecina
Publikováno v:
Cells, Vol 10, Iss 2, p 369 (2021)
The oxidative phosphorylation (OXPHOS) system localized in the inner mitochondrial membrane secures production of the majority of ATP in mammalian organisms. Individual OXPHOS complexes form supramolecular assemblies termed supercomplexes. The comple
Externí odkaz:
https://doaj.org/article/fb69cbf936c14e0794c6adb8f61629f3
Autor:
Mao Wang, Patrick Sips, Ester Khin, Maxime Rotival, Ximing Sun, Rizwan Ahmed, Anissa Anindya Widjaja, Sebastian Schafer, Permeen Yusoff, Pervinder Kaur Choksi, Nicole Shi Jie Ko, Manvendra K. Singh, David Epstein, Yuguang Guan, Josef Houštěk, Tomas Mracek, Hana Nuskova, Brittney Mikell, Jessie Tan, Francesco Pesce, Frantisek Kolar, Leonardo Bottolo, Massimiliano Mancini, Norbert Hubner, Michal Pravenec, Enrico Petretto, Calum MacRae, Stuart A Cook
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Blood supply to the heart is crucial for cardiac function. Here, the authors show that the mitochondrial tryptophanyl-tRNA synthetase, WARS2, drives blood vessel generation in zebrafish and rats and that inhibition of Wars2 diminishes blood vessel gr
Externí odkaz:
https://doaj.org/article/550ec9cd37e7417c90bb6b8603a4479c
Autor:
Nikola Kovářová, Petr Pecina, Hana Nůsková, Marek Vrbacký, Massimo Zeviani, Tomáš Mráček, Carlo Viscomi, Josef Houštěk
Publikováno v:
Data in Brief, Vol 7, Iss , Pp 1004-1009 (2016)
This paper describes data related to a research article entitled “Tissue- and species-specific differences in cytochrome c oxidase assembly induced by SURF1 defects” [1]. This paper includes data of the quantitative analysis of individual forms o
Externí odkaz:
https://doaj.org/article/a7e513412e5a4823aa1601ff38db6701
Role of Mitochondrial Glycerol-3-Phosphate Dehydrogenase in Metabolic Adaptations of Prostate Cancer
Autor:
Alena Pecinová, Lukáš Alán, Andrea Brázdová, Marek Vrbacký, Petr Pecina, Zdeněk Drahota, Josef Houštěk, Tomáš Mráček
Publikováno v:
Cells, Vol 9, Iss 8, p 1764 (2020)
Prostate cancer is one of the most prominent cancers diagnosed in males. Contrasting with other cancer types, glucose utilization is not increased in prostate carcinoma cells as they employ different metabolic adaptations involving mitochondria as a
Externí odkaz:
https://doaj.org/article/2b1e842ab00b46398a0f710c72fa7212
Autor:
Miloš Kubánek, Tereza Schimerová, Lenka Piherová, Andreas Brodehl, Alice Krebsová, Sandra Ratnavadivel, Caroline Stanasiuk, Hana Hansíková, Jiří Zeman, Tomáš Paleček, Josef Houštěk, Zdeněk Drahota, Hana Nůsková, Jana Mikešová, Josef Zámečník, Milan Macek, Petr Ridzoň, Jana Malusková, Viktor Stránecký, Vojtěch Melenovský, Hendrik Milting, Stanislav Kmoch
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 4, p 937 (2020)
Background: The pleomorphic clinical presentation makes the diagnosis of desminopathy difficult. We aimed to describe the prevalence, phenotypic expression, and mitochondrial function of individuals with putative disease-causing desmin (DES) variants
Externí odkaz:
https://doaj.org/article/9479034fcbfb4a94bc758a6f44f4de68
Autor:
David Pajuelo Reguera, Kristýna Čunátová, Marek Vrbacký, Alena Pecinová, Josef Houštěk, Tomáš Mráček, Petr Pecina
Publikováno v:
Cells, Vol 9, Iss 2, p 443 (2020)
Cytochrome c oxidase (COX) is regulated through tissue-, development- or environment-controlled expression of subunit isoforms. The COX4 subunit is thought to optimize respiratory chain function according to oxygen-controlled expression of its isofor
Externí odkaz:
https://doaj.org/article/54b8a4f3127f473086215f9b4fa599c2
Autor:
Nikola Kovářová, Tomáš Mráček, Hana Nůsková, Eliška Holzerová, Marek Vrbacký, Petr Pecina, Kateřina Hejzlarová, Katarína Kľučková, Jakub Rohlena, Jiri Neuzil, Josef Houštěk
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71869 (2013)
Mitochondrial respiratory chain is organised into supramolecular structures that can be preserved in mild detergent solubilisates and resolved by native electrophoretic systems. Supercomplexes of respiratory complexes I, III and IV as well as multime
Externí odkaz:
https://doaj.org/article/76d0d12defb74322a7150c596dcb1190