Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Josef Horak"'
Autor:
Josef Horak, Ondrej Kubecek, Anna Siskova, Katerina Honkova, Irena Chvojkova, Marketa Krupova, Monika Manethova, Sona Vodenkova, Sandra García-Mulero, Stanislav John, Filip Cecka, Ludmila Vodickova, Jiri Petera, Stanislav Filip, Veronika Vymetalkova
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Despite distant metastases being the critical factor affecting patients’ survival, they remain poorly understood. Our study thus aimed to molecularly characterize colorectal cancer liver metastases (CRCLMs) and explore whether molecular profiles di
Externí odkaz:
https://doaj.org/article/e8f2282a449d4e539c6f4ba856f3ae77
Autor:
Josef Horak, Alexandra Dolnikova, Ozge Cumaogullari, Andrea Cumova, Nazila Navvabi, Ludmila Vodickova, Miroslav Levy, Michaela Schneiderova, Vaclav Liska, Ladislav Andera, Pavel Vodicka, Alena Opattova
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Cancer therapy failure is a fundamental challenge in cancer treatment. One of the most common reasons for therapy failure is the development of acquired resistance of cancer cells. DNA-damaging agents are frequently used in first-line chemotherapy re
Externí odkaz:
https://doaj.org/article/3522c5a78afe4cca8e6b702e06abe405
Autor:
Klara Cervena, Vendula Novosadova, Barbara Pardini, Alessio Naccarati, Alena Opattova, Josef Horak, Sona Vodenkova, Tomas Buchler, Pavel Skrobanek, Miroslav Levy, Pavel Vodicka, Veronika Vymetalkova
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
MicroRNAs (miRNAs) regulate gene expression in a tissue-specific manner. However, little is known about the miRNA expression changes induced by the therapy in rectal cancer (RC) patients. We evaluated miRNA expression levels before and after therapy
Externí odkaz:
https://doaj.org/article/0fce0d73d1a041b9ac949c865103fdbc
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 31:942-948
Pancreatic cancer, a complex disease, emerges as a severe health problem worldwide and it exhibits a poor prognosis and high mortality. Risk factors associated with sporadic pancreatic cancer remain poorly understood, even less is known about disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c355ee2f2230fd404493c29bf10705f
https://doi.org/10.1158/1055-9965.epi-21-1340
https://doi.org/10.1158/1055-9965.epi-21-1340
Autor:
Pavel Vodicka, Sona Vodenkova, Josef Horak, Alena Opattova, Kristyna Tomasova, Veronika Vymetalkova, Rudolf Stetina, Kari Hemminki, Ludmila Vodickova
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 885:503564
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::038c6a49e37dd04c834c3fd060c3220a
https://doi.org/10.1016/j.mrgentox.2022.503564
https://doi.org/10.1016/j.mrgentox.2022.503564
Autor:
Kristyna Tomasova, Michal Kroupa, Anna Siskova, Josef Horak, Ondrej Vycital, Vaclav Liska, Ludmila Vodickova, Pavel Vodicka
Publikováno v:
Cancer Research. 82:2316-2316
Telomere attrition is a well-known hallmark of malignancy in cancer tissue. Our study analyzed the relative telomere length in adenomas, precursor lesions of colorectal adenocarcinoma. We investigated if the accelerated telomere length shortening occ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13d333739a630e3aa995efa9447c3816
https://doi.org/10.1158/1538-7445.am2022-2316
https://doi.org/10.1158/1538-7445.am2022-2316
Autor:
Michal Kroupa, Kristyna Tomasova, Katerina Saskova, Jana Drabova, Josef Horak, Ludmila Vodickova, Jachym Rosendorf, Vaclav Liska, Pavel Vodicka
Publikováno v:
Cancer Research. 82:760-760
The most common form of genomic instability in sporadic colorectal cancer (CRC) is chromosomal instability, a phenotype characterized by a high frequency of DNA copy number gain (CNG) and loss (CNL). Given the fundamental role of chromosomal instabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15d2df71923cf84c982dd7c314087c9a
https://doi.org/10.1158/1538-7445.am2022-760
https://doi.org/10.1158/1538-7445.am2022-760
Autor:
NenoVision, Josef Horak
Publikováno v:
Proceedings of the European Microscopy Congress 2020.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::deb0cdc2738a1457a3c86603f1d8669c
https://doi.org/10.22443/rms.emc2020.508
https://doi.org/10.22443/rms.emc2020.508
Publikováno v:
Microscopy and Microanalysis. 27:2026-2027
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7eb13aa4493e3fd75626b532aae9bce1
https://doi.org/10.1017/s1431927621007364
https://doi.org/10.1017/s1431927621007364
Autor:
Andrea Cumova, Kristyna Tomasova, Ludmila Vodickova, Josef Horak, Pavel Vodicka, Radka Vaclavikova, Kamila Koucka, Karolina Seborova
Publikováno v:
Cancers, Vol 12, Iss 1713, p 1713 (2020)
Cancers
Cancers
There is ample evidence for the essential involvement of DNA repair and DNA damage response in the onset of solid malignancies, including ovarian cancer. Indeed, highpenetrance germline mutations in DNA repair genes are important players in familial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbfa45845adb058d1a3730315ffd905a
https://www.mdpi.com/2072-6694/12/7/1713
https://www.mdpi.com/2072-6694/12/7/1713