Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Josef Hoegel"'
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
ObjectiveThe development of breast cancer cells is linked to hypoxia. The hypoxia-induced factor HIF-1α influences metastasis through neovascularization. Hypoxia seems to decrease the responsiveness to hormonal treatment due to loss of estrogen rece
Externí odkaz:
https://doaj.org/article/77c45453bce74b75b086fd29bdb41dc5
Autor:
Tabea M. Hein, Philip Sander, Anwar Giryes, Jan-Olaf Reinhardt, Josef Hoegel, E. Marion Schneider
Publikováno v:
Antibiotics, Vol 8, Iss 3, p 107 (2019)
(1) Background: Genetically based hyperinflammation may play a role in pathogen defense. We here questioned whether alterations in circulating monocytes/macrophages, inflammatory biomarkers and a functional SNP (single nucleotide polymorphisms) of th
Externí odkaz:
https://doaj.org/article/e7963459ae3f4baea532587ca778ca4b
Autor:
Manuel Luedeke, Irina Coinac, Carmen M Linnert, Natalia Bogdanova, Antje E Rinckleb, Mark Schrader, Walther Vogel, Josef Hoegel, Andreas Meyer, Thilo Dörk, Christiane Maier
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34128 (2012)
Prostate cancer susceptibility has previously been associated with truncating germline variants in the gene TP53AIP1 (tumor protein p53 regulated apoptosis inducing protein 1). For two apparently recurrent mutations (p.Q22fs and p.S32X) a remarkable
Externí odkaz:
https://doaj.org/article/ede90c9e029e41d089718da47216da1a
Autor:
Josef Hoegel, Mark A. Rubin, Walter Vogel, Thomas Paiss, Francesca Demichelis, Sven Perner, Kathleen Herkommer, Christiane Maier, Rainer Kuefer, Matthias D. Hofer
Supplementary Table 1 from Genome-Wide Linkage Analysis of TMPRSS2-ERG Fusion in Familial Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2842ee96641de3095ebea2e2c58c18cd
https://doi.org/10.1158/0008-5472.22379015
https://doi.org/10.1158/0008-5472.22379015
Autor:
Jianfeng Xu, William J. Catalona, Graham G. Giles, Brian T. Helfand, Michael J. Ackerman, Janet L. Stanford, Rosalind A. Eeles, O. Cussenot, Christopher J. Klein, Melissa C. Larson, Daniel J. Schaid, Zachary C. Fogarty, Lisa A. Cannon Albright, Cheryl D. Cropp, John D. Carpten, Shannon K. McDonnell, F. Wiklund, Zsofia Kote-Jarai, Robert J. MacInnis, Tu Nguyen-Dumont, Diptasri Mandal, Joan E. Bailey-Wilson, William B. Isaacs, Shaun M. Riska, Chih-Lin Hsieh, Josef Hoegel, Elaine A. Ostrander, Liesel M. FitzGerald, Alice S. Whittemore, Lissa DeRycke, Kathleen A. Cooney, Geraldine Cancel-Tassin, Craig C. Teerlink, Nilah Monnier Ioannidis, Saurabh Bahetti, Johanna Schleutker, Melissa C. Southey, Weiva Sieh, Stephen N. Thibodeau
Publikováno v:
European Urology. 79:353-361
Background Family history of prostate cancer (PCa) is a well-known risk factor, and both common and rare genetic variants are associated with the disease. Objective To detect new genetic variants associated with PCa, capitalizing on the role of famil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f71f202ea60d5b803340336a97604fce
https://doi.org/10.1016/j.eururo.2020.07.038
https://doi.org/10.1016/j.eururo.2020.07.038
Autor:
Julia von Schnurbein, Pamela Fischer-Posovszky, Ingrid Koerber-Rosso, Hannah Rabenstein, Stephanie Brandt, Martin Wabitsch, Reiner Siebert, Josef Hoegel
Publikováno v:
Molecular and Cellular Pediatrics
Leptin (LEP) and leptin receptor (LEPR) play a major role in energy homeostasis, metabolism, and reproductive function. While effects of biallelic likely pathogenic variants (-/-) on the phenotype are well characterized, effects of mono-allelic likel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7fdfea909979303fa36050b67a20675
https://doi.org/10.1186/s40348-021-00119-7
https://doi.org/10.1186/s40348-021-00119-7
Autor:
Christiane Maier, Josef Hoegel, Maximilian Klar, Manuel Luedeke, Meta Volcic, Annette Hasenburg, Antje E. Rinckleb, Lisa Wiesmüller, Barbara Burwinkel, Walther Vogel, Helmut Deissler, Harald Surowy, Frederik Marmé, Christof Sohn, Dominic Varga
Publikováno v:
International Journal of Cancer. 142:757-768
Only a fraction of breast cancer (BC) cases can be yet explained by mutations in genes or genomic variants discovered in linkage, genome-wide association and sequencing studies. The known genes entailing medium or high risk for BC are strongly enrich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f4e87d58c867fcb580e5b700ddd8e67
https://doi.org/10.1002/ijc.31105
https://doi.org/10.1002/ijc.31105
Autor:
Harald, Surowy, Dominic, Varga, Barbara, Burwinkel, Frederik, Marmé, Christof, Sohn, Manuel, Luedeke, Antje, Rinckleb, Christiane, Maier, Helmut, Deissler, Meta, Volcic, Lisa, Wiesmüller, Annette, Hasenburg, Maximilian, Klar, Josef, Hoegel, Walther, Vogel
Publikováno v:
International journal of cancer. 142(4)
Only a fraction of breast cancer (BC) cases can be yet explained by mutations in genes or genomic variants discovered in linkage, genome-wide association and sequencing studies. The known genes entailing medium or high risk for BC are strongly enrich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::97eed323813094dc0a3191d9e960f8f6
https://pubmed.ncbi.nlm.nih.gov/29044504
https://pubmed.ncbi.nlm.nih.gov/29044504
Expression of p16 has been established as a good surrogate marker for high-risk human papillomavirus (HPV) infection in oropharyngeal squamous cell carcinoma (OPSCC) patients, and it has been associated with an improved prognosis, irrespective of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a62c855add51331d96301389d11156db
https://europepmc.org/articles/PMC5529926/
https://europepmc.org/articles/PMC5529926/
Autor:
William J. Catalona, Bo Johanneson, Kathleen Herkommer, Brian T. Helfand, Daniel J. Schaid, Henrik Grönberg, Jianfen Xu, Johanna Schleutker, James M. Farnham, Donghui Kan, Ingrid Oakley-Girvan, Antoine Valeri, Steve Edwards, Teuvo L.J. Tammela, Lingyi Lu, Chih-Lin Hsieh, Josef Hoegel, Ethan M. Lange, Olivier Cussenot, John D. Carpten, Lovise Maehle, Cheryl D. Cropp, William B. Isaacs, Geraldine Cancel-Tassin, Gianluca Severi, Sarah D. Isaacs, Elaine A. Ostrander, Dallas R. English, John L. Hopper, Douglas T. Easton, Joan E. Bailey-Wilson, Shannon K. McDonnell, Stephen N. Thibodeau, Fredrik Wiklund, Kerry Deutsch, Liesel M. FitzGerald, Alice S. Whittemore, Kathleen A. Cooney, Christiane Maier, Claire L. Simpson, Laura McIntosh, Lisa A. Cannon-Albright, Isaac J. Powell, Pål Møller, Janet L. Stanford, Scott J. Hebbring, Daniela Seminara, Patrick C. Walsh, William D. Foulkes, Michelle Guy, Monica Emanuelsson, Michael D. Badzioch, Walther Vogel, Nicola J. Camp, Ros Eeles, Graham G. Giles, Kathleen E. Wiley, S. Lilly Zheng
Publikováno v:
The Prostate. 72:410-426
BACKGROUND In spite of intensive efforts, understanding of the genetic aspects of familial prostate cancer (PC) remains largely incomplete. In a previous microsatellite-based linkage scan of 1,233 PC families, we identified suggestive evidence for li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::752ebccace8a3dd0058e79632a737b1f
https://doi.org/10.1002/pros.21443
https://doi.org/10.1002/pros.21443