Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Josef H Scheidt"'
Autor:
Andrew L. Schilb, Josef H. Scheidt, Amita M. Vaidya, Zhanhu Sun, Da Sun, Sangjoon Lee, Zheng-Rong Lu
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 1016 (2021)
Nucleic acids are promising for a variety of therapies, such as cancer therapy and the gene therapy of genetic disorders. The therapeutic efficacy of nucleic acids is reliant on the ability of their efficient delivery to the cytosol of the target cel
Externí odkaz:
https://doaj.org/article/05d85eeca6e14b68ab0a1dd323b7a976
Autor:
Amita M. Vaidya, Ryan C. W. Hall, Ramamurthy Gopalakrishnan, Zheng-Rong Lu, Nadia Ayat, Zhanhu Sun, Da Sun, Laura M Hertz, Josef H Scheidt, Andrew L Schilb
Publikováno v:
Pharmaceutical Research. 38:1405-1418
To investigate the effectiveness of targeted ECO/miR-200c in modulating tumor microenvironment and treating triple negative breast cancer (TNBC) using non-invasive magnetic resonance molecular imaging (MRMI) of extradomain B fibronectin (EDB-FN) with
Autor:
Andrew L Schilb, Wenyu Sun, Josef H Scheidt, Amirreza Naderi, Songqi Gao, Krzysztof Palczewski, Da Sun, Sang-Joon Lee, Zheng-Rong Lu, Timothy S. Kern, Cheng Wei
Publikováno v:
J Control Release
It is still a challenge to develop gene replacement therapy for retinal disorders caused by mutations in large genes, such as Stargardt disease (STGD). STGD is caused by mutations in ABCA4 gene. Previously, we have developed an effective non-viral ge
Autor:
Da Sun, Andrew L Schilb, Ryan C. W. Hall, Michelle Yin, Zheng-Rong Lu, Josef H Scheidt, X. Liu, Nadia Ayat, Zhanhu Sun, Amita M. Vaidya
Publikováno v:
Nucleic Acid Ther
Nanoparticle based siRNA formulations often suffer from aggregation and loss of function during storage. We in this study report a frozen targeted RGD-polyethylene glycol (PEG)-ECO/siβ3 nanoparticle formulation with a prolonged shelf life and preser
Autor:
Andrew L, Schilb, Nadia R, Ayat, Amita M, Vaidya, Laura M, Hertz, Ryan C, Hall, Josef H, Scheidt, Da, Sun, Zhanhu, Sun, Ramamurthy, Gopalakrishnan, Zheng-Rong, Lu
Publikováno v:
Pharmaceutical research. 38(8)
To investigate the effectiveness of targeted ECO/miR-200c in modulating tumor microenvironment and treating triple negative breast cancer (TNBC) using non-invasive magnetic resonance molecular imaging (MRMI) of extradomain B fibronectin (EDB-FN) with
Autor:
Zhanhu Sun, Zheng-Rong Lu, Amita M. Vaidya, Nadia Ayat, Da Sun, Hannah Gilmore, Xujie Liu, Siyuan He, Victoria Qian, Josef H Scheidt, Hongfa Jiang, Andrew L Schilb, William P. Schiemann
Publikováno v:
Bioconjugate chemistry. 30(3)
Long non-coding RNAs (lncRs), by virtue of their versatility and multilevel gene regulation, have emerged as attractive pharmacological targets for treating heterogenous and complex malignancies like triple-negative breast cancer (TNBC). Despite mult
Autor:
Josef H Scheidt
Publikováno v:
Journal of Nanomaterials, Vol 2019 (2019)
Carbon nanomaterials receive much attention due to enhanced mechanical and electrical properties that arise from nanoconfinement. Carbon nanotubes (CNTs) (3-dimensional) and graphene sheets (2-dimensional) have seen applications as sensors, high-stre