Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Josef Gabelsberger"'
Publikováno v:
FEMS Immunology & Medical Microbiology. 37:161-166
In a recent clinical trial we evaluated the safety and immunogenicity of a recombinant OprF-OprI vaccine consisting of the mature outer membrane protein I (OprI) and amino acids 190-342 of OprF of Pseudomonas aeruginosa in burn patients and compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36ccef76ab36eef581e94b151020086
https://doi.org/10.1016/s0928-8244(03)00072-5
https://doi.org/10.1016/s0928-8244(03)00072-5
Autor:
Marion Nonn, I. Jochmus, H. Meissner, R. T. Mller, Josef Gabelsberger, A. Schneider, John Nieland, Andreas M. Kaufmann, Lutz Gissmann, M. Drst, Manuela Schinz
Publikováno v:
International Journal of Cancer. 92:285-293
Cervical cancer has been shown to be highly associated with human papillomavirus (HPV) infection. The viral oncogenes E6 and E7 are constantly expressed by the tumor cells and are therefore targets for immunotherapy. In the present study we investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f1cd451f22c031ce1a82f13c9661d55
https://doi.org/10.1002/1097-0215(200102)9999:9999<::aid-ijc1181>3.0.co
https://doi.org/10.1002/1097-0215(200102)9999:9999<::aid-ijc1181>3.0.co
Autor:
Erika Hundt, H Schmidt-Pilger, H Domdey, Bernhard Knapp, Josef Gabelsberger, S Bauernsachs, Uwe Lenz, B U von Specht
Publikováno v:
Journal of Biotechnology. 83:3-12
Three different variants of the recombinant hybrid outer membrane protein OprF (aa 190-342)-OprI (aa 21-83) could be obtained in high yield after expression in Escherichia coli. The hybrid protein was modified N terminally, either with a minimal hist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d59a4596abd328177c59f57830f4478
https://doi.org/10.1016/s0168-1656(00)00311-4
https://doi.org/10.1016/s0168-1656(00)00311-4
Autor:
Josef Gabelsberger, Yuanyi Li, Horst Domdey, Klaus-Dieter Hungerer, Bernd-Ulrich von Specht, E. Mansouri, Erika Hundt, Bernhard Knapp, Uwe Lenz
Publikováno v:
Vaccine. 17:1663-1666
Among the numerous targets which can be used for the development of vaccines against Pseudomonas aeruginosa we focused on the outer membrane proteins OprF and OprI. The C-terminal part of OprF from aa 190 to aa 350 was investigated for its conservati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72efbb178632e67178f5bfeeb63cabc6
https://doi.org/10.1016/s0264-410x(98)00420-4
https://doi.org/10.1016/s0264-410x(98)00420-4
Autor:
Josef Gabelsberger, Hermann Tebbe, Michael Pohlscheidt, Alexander Jockwer, Melanie Jacobs, Marco Jenzsch, Josef Burg, Stefan Wolf, Joerg Thiele
Publikováno v:
Biotechnology progress. 29(1)
Increasing capacity utilization and lowering manufacturing costs are critical for pharmaceutical companies to improve their competitiveness in a challenging environment. Development of next generation cell lines, improved media formulations, applicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b488f846ee299bb3bfc379f2bf2a8a
https://pubmed.ncbi.nlm.nih.gov/23225663
https://pubmed.ncbi.nlm.nih.gov/23225663
Publikováno v:
FEMS Microbiology Letters. 109:131-137
A gene library of the hyperthermophilic bacterium Thermotoga maritima strain MSB8 was constructed in Escherichia coli. Two non-related T. maritima chromosomal DNA fragments were physically characterized. They conferred the synthesis of thermostable X
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2d9c4f0d16469377644c7cc52f6d3ba
https://doi.org/10.1111/j.1574-6968.1993.tb06157.x
https://doi.org/10.1111/j.1574-6968.1993.tb06157.x
Autor:
Ulrich Baumann, Joachim Freihorst, Hartmut Hagemann, Bernd Ulrich von Specht, Josef Gabelsberger, Heinz P Hahn, Kerstin Göcke
Publikováno v:
FEMS immunology and medical microbiology. 37(2-3)
We compared the immunogenicity of two vaccination schedules with either a systemic or a mucosal booster, both following a mucosal primary vaccination with a recombinant outer membrane fusion protein of Pseudomonas aeruginosa (OprF-I) in 12 healthy vo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1c165ee0c7a1f36bcd627e66b4b901
https://pubmed.ncbi.nlm.nih.gov/12832121
https://pubmed.ncbi.nlm.nih.gov/12832121
Autor:
Gabriele Köhler, M Larbig, Klaus-Dieter Hungerer, J Freihorst, E. Mansouri, Bernhard Knapp, Josef Gabelsberger, B U von Specht, H Domdey, Burkhard Tümmler, Erika Hundt
Publikováno v:
Vaccine. 19(17-19)
A hybrid protein [Met-Ala-(His)(6) OprF(190-342)-OprI(21-83)] consisting of the mature outer membrane protein I (OprI) and amino acids 190-342 of OprF of Pseudomonas aeruginosa was expressed in Escherichia coli and purified by Ni(2+) chelate-affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::521712fba1558f9f86972e4462532222
https://pubmed.ncbi.nlm.nih.gov/11257350
https://pubmed.ncbi.nlm.nih.gov/11257350
Autor:
Bernd-Ulrich von Specht, Horst Domdey, Klaus-Dieter Hungerer, Erika Hundt, Harry E. Gilleland, Knapp Bernhard, John Staczek, Josef Gabelsberger, Uwe Lenz, E. Mansouri
Publikováno v:
Infection and immunity. 67(3)
A hybrid protein [Met-Ala-(His) 6 OprF 190–342 -OprI 21–83 ] consisting of the mature outer membrane protein I (OprI) and amino acids 190 to 342 of OprF of Pseudomonas aeruginosa was expressed in Escherichia coli and purified by Ni 2+ chelate-aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcec4efef5b044be3626a50ec845a8f0
https://pubmed.ncbi.nlm.nih.gov/10024596
https://pubmed.ncbi.nlm.nih.gov/10024596
Publikováno v:
FEMS immunology and medical microbiology. 20(2)
Human interleukin-6 (hIL-6) cDNA was genetically fused with the Escherichia coli hemolysin secretorial signal (hlyA[S]) sequence in a plasmid vector. Recombinant E. coli XL-1 Blue and attenuated Salmonella typhimurium secreted a 30 kDa hIL-6-HlyA(S)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcdb5fa0c2229531360b5c3ae589bc76
https://pubmed.ncbi.nlm.nih.gov/9544778
https://pubmed.ncbi.nlm.nih.gov/9544778