Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Josef Christensen"'
Autor:
Xuefeng Sun, Rebecca S. D’Urso, Jonathon M. Muncie, Valerie M. Weaver, Andrew S. Brack, Josef Christensen, Susan Eliazer
Publikováno v:
Cell Stem Cell
Cell stem cell, vol 25, iss 5
Cell stem cell, vol 25, iss 5
Summary Satellite cells (SCs) reside in a dormant state during tissue homeostasis. The specific paracrine agents and niche cells that maintain SC quiescence remain unknown. We find that Wnt4 produced by the muscle fiber maintains SC quiescence throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a826f3fd4f97cedf7fdccfc401e39a
https://pubmed.ncbi.nlm.nih.gov/31495781
https://pubmed.ncbi.nlm.nih.gov/31495781
Autor:
Kyle Serikawa, Peter W. H. Holland, John F Mulley, Adam D Hargreaves, Guojie Zhang, Peter Gildsig Jansen, Ferdinand Marlétaz, Brian A. Fox, Signe Vendelbo Horn Pedersen, R. Scott Heller, Matilde Thye Hansen, Enrico Spiga, Shiping Liu, William R. Taylor, Long Zhou, Fang Li, Josef Christensen, Shameek Biswas
Publikováno v:
Hargreaves, A D, Zhou, L, Christensen, J, Marlétaz, F, Liu, S, Li, F, Jansen, P G, Spiga, E, Hansen, M T, Pedersen, S V H, Biswas, S, Serikawa, K, Fox, B A, Taylor, W R, Mulley, J F, Zhang, G, Heller, R S & Holland, P W H 2017, ' Genome sequence of a diabetes-prone rodent reveals a mutation hotspot around the ParaHox gene cluster ', Proceedings of the National Academy of Sciences of the United States of America, vol. 114, no. 29, pp. 7677-7682 . https://doi.org/10.1073/pnas.1702930114
Significance A core question in evolutionary biology is how mutation and selection adapt and constrain species to specialized habitats. We sequenced the genome of the sand rat, a desert rodent susceptible to nutritionally induced diabetes, and discov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841ca8d9c38b5c1b7001062aa9c8fd81
https://curis.ku.dk/portal/da/publications/genome-sequence-of-a-diabetesprone-rodent-reveals-a-mutation-hotspot-around-the-parahox-gene-cluster(d7dbe76b-ad99-45e5-b233-0a905ab723ea).html
https://curis.ku.dk/portal/da/publications/genome-sequence-of-a-diabetesprone-rodent-reveals-a-mutation-hotspot-around-the-parahox-gene-cluster(d7dbe76b-ad99-45e5-b233-0a905ab723ea).html
Autor:
Josef Christensen, Joe V. Chakkalakal, Francesca S. Boscolo, Alessandra Sacco, Andrew S. Brack, Wanyi Xiang, Mathew T. Tierney
Publikováno v:
Development (Cambridge, England)
Across different niches, subsets of highly functional stem cells are maintained in a relatively dormant rather than proliferative state. Our understanding of proliferative dynamics in tissue-specific stem cells during conditions of increased tissue t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd4c4f26a156ea2cb8783deffbe00f8a
https://doi.org/10.1242/dev.100842
https://doi.org/10.1242/dev.100842
Autor:
Peter W. H. Holland, R. Scott Heller, Brian A. Fox, Fang Li, Shiping Liu, Kyle Serikawa, Matilde Thye Hansen, Signe Vendelbo Horn Pedersen, John F Mulley, Ferdinand Marlétaz, Enrico Spiga, Josef Christensen, Adam D Hargreaves, Guojie Zhang, Peter Gildsig Jansen, William R. Taylor, Long Zhou, Shameek Biswas
The sand ratPsammomys obesusis a gerbil native to deserts of North Africa and the Middle East1. Sand rats survive with low caloric intake and when given high carbohydrate diets can become obese and develop type II diabetes2which, in extreme cases, le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b24eb13bf3a31876bdac8fa31f433b34
https://doi.org/10.1101/093401
https://doi.org/10.1101/093401
Publikováno v:
Developmental Dynamics. 238:2014-2024
The signaling mechanisms regulating pluripotency in porcine embryonic stem cells and embryos are unknown. In this study, we characterize cell signaling in the in-vivo porcine inner cell mass and later-stage epiblast. We evaluate expression of OCT4, N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9a8c992a647df8c1e779f6ed03fe310
https://doi.org/10.1002/dvdy.22027
https://doi.org/10.1002/dvdy.22027
Publikováno v:
Reproduction, Fertility and Development. 21:191
Pluripotency in mice and human embryonic stem cells is regulated by a number of transcription factors, notably including Oct-4, Sox-2, and Nanog. However, in the pig, previous research indicates that Oct-4 protein and mRNA is not specifically localiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::845caf55a14a7ce1e1949bb08b46aaa0
https://doi.org/10.1071/rdv21n1ab185
https://doi.org/10.1071/rdv21n1ab185