Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Josef, Zadrazil"'
Autor:
Jana Jemelkova, Milada Stuchlova Horynova, Petr Kosztyu, Katerina Zachova, Josef Zadrazil, Dana Galuszkova, Kazuo Takahashi, Jan Novak, Milan Raska
Publikováno v:
Kidney International Reports, Vol 8, Iss 5, Pp 1068-1075 (2023)
Introduction: Immunoglobulin A1 (IgA1) with galactose-deficient O-glycans (Gd-IgA1) play a key role in the pathogenesis of IgA nephropathy (IgAN). Mucosal-tissue infections increase IL-6 production and, in patients with IgAN, are often associated wit
Externí odkaz:
https://doaj.org/article/9f298502b83846878de889d7aa0b4ecc
Autor:
Nadezda Petejova, Arnost Martinek, Josef Zadrazil, Viktor Klementa, Lenka Pribylova, Radim Bris, Marcela Kanova, Radka Sigutova, Ivana Kacirova, Zdenek Svagera, Eva Bace, David Stejskal
Publikováno v:
BMC Nephrology, Vol 23, Iss 1, Pp 1-18 (2022)
Abstract Background Through regulation of signaling pathways, microRNAs (miRNAs) can be involved in sepsis and associated organ dysfunction. The aims of this study were to track the 7-day time course of blood miRNAs in patients with sepsis treated wi
Externí odkaz:
https://doaj.org/article/31b1a643925c48e4b36ada4ec737d7e9
Autor:
Katerina Zachova, Petr Kosztyu, Josef Zadrazil, Karel Matousovic, Karel Vondrak, Petr Hubacek, Klara Kostovcikova, Helena Tlaskalova Hogenova, Jiri Mestecky, Milan Raska
Publikováno v:
Biomedical Papers, Vol 164, Iss 3, Pp 247-254 (2020)
Aims: Epstein-Barr virus (EBV) targets predominantly B cells and these cells could acquire new phenotype characteristics. Here we analyzed whether EBV-infected and -uninfected B cells from healthy subjects differ in proportion of dominant phenotypes,
Externí odkaz:
https://doaj.org/article/c79a8d1ab0aa4c6e86eb7fbfa9d9721e
Autor:
Jiri Orsag, David Karasek, Milan Halenka, Helena Vaverkova, Jaromira Spurna, Veronika Kubickova, Jiri Lukes, Josef Zadrazil
Publikováno v:
Biomedical Papers, Vol 163, Iss 2, Pp 166-171 (2019)
Background: Diseases caused by atherosclerosis play the most important role in mortality and morbidity worldwide. Serum adipocyte fatty acid binding protein (A-FABP) seems to be a new promising marker to determine the risk of atherosclerosis. Objecti
Externí odkaz:
https://doaj.org/article/db4de68912b74c4e8aa04572f6aeb970
Publikováno v:
Renal Failure, Vol 41, Iss 1, Pp 576-594 (2019)
Substances toxic to the kidney are legion in the modern world. The sheer number and variety, their mutual interactions and, metabolism within the body are a challenge to research. Moreover, the kidney is especially prone to injury owing to its physio
Externí odkaz:
https://doaj.org/article/6ba890c8342f49488962bfa4652b528c
Autor:
Katerina Zachova, Petr Kosztyu, Josef Zadrazil, Karel Matousovic, Karel Vondrak, Petr Hubacek, Bruce A. Julian, Zina Moldoveanu, Zdenek Novak, Klara Kostovcikova, Milan Raska, Jiri Mestecky
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
IgA nephropathy (IgAN) is the dominant type of primary glomerulonephritis worldwide. However, IgAN rarely affects African Blacks and is uncommon in African Americans. Polymeric IgA1 with galactose-deficient hinge-region glycans is recognized as auto-
Externí odkaz:
https://doaj.org/article/beb2f4e99f604688887524e5bc2314c4
Autor:
Ladislav Stepanek, Dagmar Horakova, Marie Nakladalova, Lubica Cibickova, David Karasek, Josef Zadrazil
Publikováno v:
Biomedical Papers, Vol 162, Iss 4, Pp 249-257 (2018)
Prediabetes is a glucose metabolism disorder considered as a distinct nosological entity which strongly predicts the development of type 2 diabetes mellitus. This nosological entity itself is a serious condition indicating an increased risk of athero
Externí odkaz:
https://doaj.org/article/e2f093d73fe14fcc96b8453527933865
Publikováno v:
Biomedical Papers, Vol 162, Iss 3, Pp 165-177 (2018)
BK virus nephropathy (BKVN) is a serious opportunistic infection threatening renal function especially during the first year after transplantation. Its incidence is now on the rise and is closely related to the level of the recipient's immune system
Externí odkaz:
https://doaj.org/article/97643ffcfdc74670a25e1f7550205c69
Autor:
Petr Kosztyu, Martin Hill, Jana Jemelkova, Lydie Czernekova, Leona Raskova Kafkova, Miroslav Hruby, Karel Matousovic, Karel Vondrak, Josef Zadrazil, Ivan Sterzl, Jiri Mestecky, Milan Raska
Publikováno v:
Kidney & Blood Pressure Research, Vol 43, Iss 2, Pp 350-359 (2018)
Background/Aims: IgA nephropathy is associated with aberrant O-glycosylation of IgA1, which is recognized by autoantibodies leading to the formation of circulating immune complexes. Some of them, after deposition into kidney mesangium, trigger glomer
Externí odkaz:
https://doaj.org/article/57f47fc2fc59432991c238c9c39f9f3b
Autor:
Anna Petrackova, Andrea Smrzova, Petr Gajdos, Marketa Schubertova, Petra Schneiderova, Pavel Kromer, Vaclav Snasel, Martina Skacelova, Frantisek Mrazek, Josef Zadrazil, Pavel Horak, Eva Kriegova
Publikováno v:
Clinical Proteomics, Vol 14, Iss 1, Pp 1-15 (2017)
Abstract Background Systemic lupus erythematosus (SLE) is a remarkably heterogeneous autoimmune disease. Despite tremendous efforts, our knowledge of serum protein patterns in severe SLE phenotypes is still limited. We investigated the serum protein
Externí odkaz:
https://doaj.org/article/f2cd299f5d83405981961bc58eafaf81