Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Josef, Vagner"'
Autor:
Bianca N. Mason, Shayne N. Hassler, Kathryn DeFea, Scott Boitano, Josef Vagner, Theodore J. Price, Greg Dussor
Publikováno v:
The Journal of Headache and Pain, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Migraine is a severely debilitating disorder that affects millions of people worldwide. Studies have indicated that activation of protease-activated receptor-2 (PAR2) in the dura mater causes headache responses in preclinical mode
Externí odkaz:
https://doaj.org/article/e59629c7f6954a7284df0a868cea63a5
Autor:
Moeno Kume, Ayesha Ahmad, Stephanie Shiers, Michael D. Burton, Kathryn A. DeFea, Josef Vagner, Gregory Dussor, Scott Boitano, Theodore J. Price
Publikováno v:
The Journal of Pain. 24:605-616
Given the limited options and often harmful side effects of current analgesics and the suffering caused by the opioid crisis, new classes of pain therapeutics are needed. Protease-activated receptors (PARs), particularly PAR2, are implicated in a var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a29fc0d7e3afb63b1cdbfda3e539bad
https://doi.org/10.1016/j.jpain.2022.11.006
https://doi.org/10.1016/j.jpain.2022.11.006
Autor:
Hillary V. Schiff, Candy M. Rivas, William P. Pederson, Estevan Sandoval, Samuel Gillman, Joy Prisco, Moeno Kume, Gregory Dussor, Josef Vagner, Julie G. Ledford, Theodore J. Price, Kathryn A. DeFea, Scott Boitano
Publikováno v:
British Journal of Pharmacology. 180:667-680
Asthma is a heterogenous disease strongly associated with inflammation that has many different causes and triggers. Current asthma treatments target symptoms such as bronchoconstriction and airway inflammation. Despite recent advances in biological t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f12b41a8edcf2479b562cc26fc2a78
https://doi.org/10.1111/bph.15903
https://doi.org/10.1111/bph.15903
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Pharmacogenomics and Translational Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36b7dcb2d6b595ff263ae1e0c2845be1
https://doi.org/10.1124/jpet.122.550630
https://doi.org/10.1124/jpet.122.550630
Autor:
Samuel Gillman, Hillary Schiff, Wil Pederson, Estevan Sandoval, Benjamin Rivera, Gregory Dussor, Theodore Price, Josef Vagner, Kathryn Defea, Scott Boitano
Publikováno v:
Physiology. 38
Asthma is a complex disease characterized by airway hyperresponsiveness (AHR) inflammation, and mucus overproduction, and has differential presentation in males and females. There exists strong demand to improve upon current asthma treatments by targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::265ce672be725c96c4242e5235e27310
https://doi.org/10.1152/physiol.2023.38.s1.5734467
https://doi.org/10.1152/physiol.2023.38.s1.5734467
Autor:
Hillary Schiff, Samuel Gillman, William Pederson, Gregory Dussor, Theodore Price, Josef Vagner, Kathryn DeFea, Scott Boitano
Publikováno v:
Physiology. 38
Biased signaling in G protein-coupled receptors (GPCRs) has emerged as a target for drug development. Protease-activated receptor-2 (PAR2) is a GPCR present in the airway epithelium with biased signaling that has been shown to trigger both detrimenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2a9f318a62f26e690b7e0d463f05d7a
https://doi.org/10.1152/physiol.2023.38.s1.5734466
https://doi.org/10.1152/physiol.2023.38.s1.5734466
Autor:
Robert J. Gillies, Victor J. Hruby, Eugene A. Mash, Haiyong Han, Brenda Baggett, David L. Morse, Ronald M. Lynch, Jatinder Josan, Josef Vagner, Liping Xu
A novel approach to specifically target tumor cells for detection and treatment is the proposed use of heteromultivalent ligands, which are designed to interact with, and noncovalently crosslink, multiple different cell surface receptors. Although en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f12fcb85ef528fa8bcaa799d7065c11
https://doi.org/10.1158/1535-7163.c.6531459
https://doi.org/10.1158/1535-7163.c.6531459
Autor:
Robert J. Gillies, Victor J. Hruby, Eugene A. Mash, Haiyong Han, Brenda Baggett, David L. Morse, Ronald M. Lynch, Jatinder Josan, Josef Vagner, Liping Xu
Supplementary Figures 1-6 from Enhanced targeting with heterobivalent ligands
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1998e4e68b92bc782904b5e3e98f64ac
https://doi.org/10.1158/1535-7163.22484562.v1
https://doi.org/10.1158/1535-7163.22484562.v1
Autor:
David L. Morse, Robert J. Gillies, Stephen R. Grobmyer, Josef Vagner, Bradford W. Carter, Dominique Abrahams, Alexis S. Lopez, Steven A. Enkemann, Mark C. Lloyd, Kellsey Bishop, Marilyn M. Bui, Narges K. Tafreshi
PDF file - 1.5MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b34c5b0fcc16566780c8f7dcb7c999
https://doi.org/10.1158/1078-0432.22445811
https://doi.org/10.1158/1078-0432.22445811
Autor:
David L. Morse, Robert J. Gillies, Stephen R. Grobmyer, Josef Vagner, Bradford W. Carter, Dominique Abrahams, Alexis S. Lopez, Steven A. Enkemann, Mark C. Lloyd, Kellsey Bishop, Marilyn M. Bui, Narges K. Tafreshi
Purpose: To develop targeted molecular imaging probes for the noninvasive detection of breast cancer lymph node metastasis.Experimental Design: Six cell surface or secreted markers were identified by expression profiling and from the literature as be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c43ab44166a913f307f9345c6bb7d8f
https://doi.org/10.1158/1078-0432.c.6520566.v1
https://doi.org/10.1158/1078-0432.c.6520566.v1