The Phosphocarrier Protein HPr Contributes to Meningococcal Survival during Infection.

Autor: Ana Antunes, Meriem Derkaoui, Aude Terrade, Mélanie Denizon, Ala-Eddine Deghmane, Josef Deutscher, Isabel Delany, Muhamed-Kheir Taha

Publikováno v: PLoS ONE, Vol 11, Iss 9, p e0162434 (2016)

Neisseria meningitidis is an exclusively human pathogen frequently carried asymptomatically in the nasopharynx but it can also provoke invasive infections such as meningitis and septicemia. N. meningitidis uses a limited range of carbon sources durin

Externí odkaz: https://doaj.org/article/46ab6f7135df4fdcb80f21e8b2d7c216

Enterococcus faecalis Maltodextrin Gene Regulation by Combined Action of Maltose Gene Regulator MalR and Pleiotropic Regulator CcpA

Autor: Axel Hartke, Maxime Grand, Nicolas Sauvageot, Josef Deutscher, Eliette Riboulet-Bisson

Publikováno v: Appl Environ Microbiol
Applied and Environmental Microbiology
Applied and Environmental Microbiology, American Society for Microbiology, 2020, 86 (18), ⟨10.1128/AEM.01147-20⟩

Enterococci are Gram-positive bacteria present in the healthy human microbiota, but they are also a leading cause of nosocomial infections. Maltodextrin utilization by Enterococcus faecalis has been identified as an important factor for colonization

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7402bd529509ffabfc9f612c535590e
https://doi.org/10.1128/aem.01147-20

Photoinactivation of the Staphylococcus aureus Lactose-Specific EIICB Phosphotransferase Component with p-azidophenyl-β-D-Galactoside and Phosphorylation of the Covalently Bound Substrate

Autor: Pierre Briozzo, Gina Sossna-Wunder, Josef Deutscher, Wolfgang Hengstenberg

Publikováno v: Microbial Physiology. 28:147-158

Background: The phosphoenolpyruvate (PEP):lactose phosphotransferase system of Staphylococcus aureus transports and phosphorylates lactose and various phenylgalactosides. Their phosphorylation is catalyzed by the Cys476-phosphorylated EIIB domain of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::46779f57ab203f3eb345ebdad0d8e3d7
https://doi.org/10.1159/000494433

Structural basis for the regulation mechanism of the tyrosine kinase CapB from Staphylococcus aureus.

Autor: Vanesa Olivares-Illana, Philippe Meyer, Emmanuelle Bechet, Virginie Gueguen-Chaignon, Didier Soulat, Sylvie Lazereg-Riquier, Ivan Mijakovic, Josef Deutscher, Alain J Cozzone, Olivier Laprévote, Solange Morera, Christophe Grangeasse, Sylvie Nessler

Publikováno v: PLoS Biology, Vol 6, Iss 6, p e143 (2008)

Bacteria were thought to be devoid of tyrosine-phosphorylating enzymes. However, several tyrosine kinases without similarity to their eukaryotic counterparts have recently been identified in bacteria. They are involved in many physiological processes

Externí odkaz: https://doaj.org/article/0389812f019f4d8c938d70a3a0b7d8e6

Enterococcus faecalis MalR acts as a repressor of the maltose operons and additionally mediates their catabolite repression via direct interaction with seryl-phosphorylated-HPr

Autor: Martín Espariz, Victor Sebastian Blancato, Andreas Pikis, Josef Deutscher, Nicolas Sauvageot, Axel Hartke, Maxime Grand, Christian Magni

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Molecular Microbiology
Molecular Microbiology, Wiley, 2019, ⟨10.1111/mmi.14431⟩
Molecular Microbiology, Wiley, 2019, pp.464-477. ⟨10.1111/mmi.14431⟩

Enterococci are gram-positive pathogens and lead to cause hospital-acquired infections worldwide. Central carbon metabolism was shown as highly induced in Enterococcus faecalis during infection context. Metabolism of α-polysaccharides was previously

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9103e4a35fe85575badd0ec664fdbae5
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