Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Josean Cruz"'
Autor:
Vedad Delic, Kenyaria Noble, Sandra Zivkovic, Tam-Anh Phan, Christian Reynes, Yumeng Zhang, Oluwakemi Phillips, Charles Claybaker, Yen Ta, Vinh B. Dinh, Josean Cruz, Tomas A. Prolla, Patrick C. Bradshaw
Publikováno v:
Biology Open, Vol 7, Iss 11 (2018)
Mitochondrial DNA mutations accumulate with age and may play a role in stem cell aging as suggested by the premature aging phenotype of mitochondrial DNA polymerase gamma (POLG) exonuclease-deficient mice. Therefore, E1A immortalized murine embryonic
Externí odkaz:
https://doaj.org/article/12f041ef73ae4a4a9200095ac577b7f1
Autor:
Crupa Kurien, Daniel Hennessey, Josean Cruz, Sandra Zivkovic, Jennifer Barretta, Jared Ehrhart, Jaheem Joseph, Vedad Delic, Alison E. Willing, Svitlana Garbuzova-Davis, Patrick C. Bradshaw, Avery Thomson
Publikováno v:
Journal of Neuroscience Research. 96:1353-1366
Amyotrophic lateral sclerosis (ALS) is an adult onset neurodegenerative disease characterized by progressive motor neuron degeneration in the brain and spinal cord leading to muscle atrophy, paralysis, and death. Mitochondrial dysfunction is a major
Autor:
Henry Gong, Sandra Zivkovic, Umesh K. Jinwal, Vinh B. Dinh, Dale Chaput, Devon Placides, Yumeng Zhang, Stanley M. Stevens, Eni Cvitkovic, Ernide Frederic, Vedad Delic, Tam-Anh Phan, Christian Reynes, Daniel C. Lee, Josean Cruz, Hamed Mirzaei, Jeddidiah W. D. Griffin, Patrick C. Bradshaw
Publikováno v:
NeuroMolecular Medicine. 19:322-344
Parkinson's disease (PD) is a neurodegenerative disorder characterized by alpha-synuclein accumulation and loss of dopaminergic neurons in the substantia nigra (SN) region of the brain. Increased levels of alpha-synuclein have been shown to result in