Chronic Administration of Cannabinoid Receptor 2 Agonist (JWH-133) Increases Ectopic Ovarian Tumor Growth and Endocannabinoids (Anandamide and 2-Arachidonoyl Glycerol) Levels in Immunocompromised SCID Female Mice

Autor: Henry L. Blanton, Melissa C. McHann, Haley De Selle, Canice Lei Dancel, Jose-Luis Redondo, Deborah Molehin, Nadezhda A. German, Scott Trasti, Kevin Pruitt, Isabel Castro-Piedras, Josée Guindon

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

Cannabinoid-based therapies are increasingly being used by cancer patients to treat chemotherapy-induced nausea and vomiting. Recently, cannabinoids have gained increased attention for their effects on cancer growth. Indeed, the effect of CB2 (JWH-01

Externí odkaz: https://doaj.org/article/430f2198d6a444b48ecedc0c4ae931da

Efficient Clustering from Distributions over Topics

Autor: Badenes-Olmedo, Carlos, García, Jose-Luis Redondo, Corcho, Oscar

Publikováno v: ACM Proceedings of the Knowledge Capture Conference, article 17, K-CAP 2017

There are many scenarios where we may want to find pairs of textually similar documents in a large corpus (e.g. a researcher doing literature review, or an R&D project manager analyzing project proposals). To programmatically discover those connectio

Externí odkaz: http://arxiv.org/abs/2012.08206

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Scalable Cross-lingual Document Similarity through Language-specific Concept Hierarchies

Autor: Carlos Badenes-Olmedo, Oscar Corcho, Jose-Luis Redondo García

Publikováno v: Proceedings of the 10th International Conference on Knowledge Capture-K-CAP 19
Proceedings of the 10th International Conference on Knowledge Capture -K-CAP '19
Proceedings of the 10th International Conference on Knowledge Capture

With the ongoing growth in number of digital articles in a wider set of languages and the expanding use of different languages, we need annotation methods that enable browsing multi-lingual corpora. Multilingual probabilistic topic models have recent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f9dace77df58a2d0a9e977ce8fdbac6

Effective Reduction in High Ethanol Drinking by Semisynthetic Tetracycline Derivatives

Autor: Yazan M. Al-Hasan, Jessica A. Groot, Peter J. Syapin, David R. M. Trotter, Joseph M. Martinez, David C. Curtis, Patrick C. Marquardt, Carol Baby, Clayton L. Allison, Matthew J. Scheible, Susan E. Bergeson, David S. Edwards, Jose Luis Redondo, Katy T. Nicholson, Ismael Segura-Ulate

Publikováno v: Alcoholism: Clinical and Experimental Research. 40:2482-2490

Background New pharmacotherapies to treat alcohol use disorders (AUD) are needed. Given the complex nature of AUD, there likely exist multiple novel drug targets. We, and others, have shown that the tetracycline drugs, minocycline and doxycycline, re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d8bf7cb14c5efccf0f6459874198a934
https://doi.org/10.1111/acer.13253