Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Jose-Luis Gonzalez De Aguilar"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are fatal adult-onset neurodegenerative disorders that share clinical, neuropathological and genetic features, which forms part of a multi-system disease spectrum. The pathological
Externí odkaz:
https://doaj.org/article/4970d2df26f34fb4864b34caca78d6c8
Autor:
Aroona Razzaq, Ghulam Hussain, Azhar Rasul, Jiaqi Xu, Qiqi Zhang, Shoaib Ahmad Malik, Haseeb Anwar, Nimra Aziz, Nady Braidy, Jose-Luis Gonzalez de Aguilar, Wei Wei, Jiang Li, Xiaomeng Li
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Peripheral nerve injury is a debilitating condition that may lead to partial or complete motor, sensory and autonomic function loss and lacks effective therapy until date. Therefore, it is quite imperative to explore impending rem
Externí odkaz:
https://doaj.org/article/5d182dcf9df64f4dbbb378b65fd394a3
Autor:
Alexandre Henriques, Stefan Kastner, Oliver Wafzig, Jose-Luis Gonzalez De Aguilar, Armin Schneider
Publikováno v:
Genomics Data, Vol 4, Iss C, Pp 47-49 (2015)
Granulocyte-colony stimulating factor (G-CSF) has been recently identified as a neurotrophic factor able to preserve motor functions, rescue motor units and extent survival in an animal model of amyotrophic lateral sclerosis, the SOD1 G93A mice. To g
Externí odkaz:
https://doaj.org/article/b4e3e7997f1b4e5ea21e5b85d675d7bf
Autor:
Anissa Fergani, Hugues Oudart, Jose-Luis Gonzalez De Aguilar, Bastien Fricker, Frédérique René, Jean-François Hocquette, Vincent Meininger, Luc Dupuis, Jean-Philippe Loeffler
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 7, Pp 1571-1580 (2007)
Amyotrophic lateral sclerosis (ALS) is the most common adult motor neuron disease, causing motor neuron degeneration, muscle atrophy, paralysis, and death. Despite this degenerative process, a stable hypermetabolic state has been observed in a large
Externí odkaz:
https://doaj.org/article/5d8e59cc20d24c319fb6b046d2d78211
Autor:
Alexandre Henriques, Hélène Blasco, Marie-Céline Fleury, Philippe Corcia, Andoni Echaniz-Laguna, Laura Robelin, Gabrielle Rudolf, Thiebault Lequeu, Martine Bergaentzle, Christian Gachet, Pierre-François Pradat, Eric Marchioni, Christian R Andres, Christine Tranchant, Jose-Luis Gonzalez De Aguilar, Jean-Philippe Loeffler
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131512 (2015)
Growing evidence supports a link between fatty acid metabolism and amyotrophic lateral sclerosis (ALS). Here we determined the fatty acid composition of blood lipids to identify markers of disease progression and survival. We enrolled 117 patients fr
Externí odkaz:
https://doaj.org/article/379a0b12c66e4d7892c8808b0f8d0aa7
Autor:
Luc Dupuis, Jose-Luis Gonzalez de Aguilar, Franck di Scala, Frédérique Rene, Marc de Tapia, Pierre-François Pradat, Lucette Lacomblez, Danielle Seihlan, Rabinder Prinjha, Frank S. Walsh, Vincent Meininger, Jean-Philippe Loeffler
Publikováno v:
Neurobiology of Disease, Vol 10, Iss 3, Pp 358-365 (2002)
Amyotrophic lateral sclerosis (ALS) is a fatal neurological disorder characterized by the selective degeneration of upper and lower motor neurons. The lack of a molecular diagnostic marker is of increasing concern in view of the therapeutic strategie
Externí odkaz:
https://doaj.org/article/e3a08211dd8a453b8f6ee101a96606ab
Autor:
Ghulam Hussain, Florent Schmitt, Alexandre Henriques, Thiebault Lequeu, Frederique Rene, Françoise Bindler, Sylvie Dirrig-Grosch, Hugues Oudart, Lavinia Palamiuc, Marie-Helene Metz-Boutigue, Luc Dupuis, Eric Marchioni, Jose-Luis Gonzalez De Aguilar, Jean-Philippe Loeffler
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e64525 (2013)
The progressive deterioration of the neuromuscular axis is typically observed in degenerative conditions of the lower motor neurons, such as amyotrophic lateral sclerosis (ALS). Neurodegeneration in this disease is associated with systemic metabolic
Externí odkaz:
https://doaj.org/article/02d48fae28e6473693aef1fd013b64e0
Autor:
Luc Dupuis, Jose-Luis Gonzalez de Aguilar, Andoni Echaniz-Laguna, Judith Eschbach, Frédérique Rene, Hugues Oudart, Benoit Halter, Caroline Huze, Laurent Schaeffer, Frédéric Bouillaud, Jean-Philippe Loeffler
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5390 (2009)
BACKGROUND:Amyotrophic lateral sclerosis (ALS), the most frequent adult onset motor neuron disease, is associated with hypermetabolism linked to defects in muscle mitochondrial energy metabolism such as ATP depletion and increased oxygen consumption.
Externí odkaz:
https://doaj.org/article/2e994e21daa34b18b313e1754ba3e414
Autor:
Jose-Luis Gonzalez de Aguilar, Nimra Aziz, Jing Wang, Rashad Hussain, Aroona Razzaq, Muhammad Qasim, Tao Sun, Shamaila Zafar, Ghulam Hussain, Azhar Rasul, Haseeb Anwar
Publikováno v:
International Journal of Biological Sciences
Peripheral nerve injury is a complex condition with a variety of signs and symptoms such as numbness, tingling, jabbing, throbbing, burning or sharp pain. Peripheral nerves are fragile in nature and can easily get damaged due to acute compression or
Autor:
Wei Wei, Jiaqi Xu, Haseeb Anwar, Shoaib Ahmad Malik, Jiang Li, Xiaomeng Li, Nimra Aziz, Aroona Razzaq, Qiqi Zhang, Ghulam Hussain, Jose-Luis Gonzalez de Aguilar, Nady Braidy, Azhar Rasul
Publikováno v:
BMC Complementary Medicine and Therapies
BMC Complementary Medicine and Therapies, 2020, 20 (1), pp.181. ⟨10.1186/s12906-020-02950-3⟩
BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-11 (2020)
BMC Complementary Medicine and Therapies, 2020, 20 (1), pp.181. ⟨10.1186/s12906-020-02950-3⟩
BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-11 (2020)
Background Peripheral nerve injury is a debilitating condition that may lead to partial or complete motor, sensory and autonomic function loss and lacks effective therapy until date. Therefore, it is quite imperative to explore impending remedies for