Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Jose Zavala"'
Autor:
Ngoc Vu, Tobias M. Maile, Sudha Gollapudi, Aleksandr Gaun, Phillip Seitzer, Jonathon J. O’Brien, Sean R. Hackett, Jose Zavala-Solorio, Fiona E. McAllister, Ganesh Kolumam, Rob Keyser, Bryson D. Bennett
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 9, Pp 100607- (2024)
Blood plasma is one of the most commonly analyzed and easily accessible biological samples. Here, we describe an automated liquid-liquid extraction platform that generates accurate, precise, and reproducible samples for metabolomic, lipidomic, and pr
Externí odkaz:
https://doaj.org/article/4c2c7606b1f34ce2a12d36d49f908b45
Autor:
Mark Z. Chen, Joshua C. Chang, Jose Zavala-Solorio, Lance Kates, Minh Thai, Annie Ogasawara, Xiaobo Bai, Sean Flanagan, Victor Nunez, Khanhky Phamluong, James Ziai, Robert Newman, Søren Warming, Ganesh Kolumam, Junichiro Sonoda
Publikováno v:
Molecular Metabolism, Vol 6, Iss 11, Pp 1454-1467 (2017)
Objective: Fibroblast Growth Factor 21 (FGF21) is a potent stimulator of brown fat thermogenesis that improves insulin sensitivity, ameliorates hepatosteatosis, and induces weight loss by engaging the receptor complex comprised of Fibroblast Growth F
Externí odkaz:
https://doaj.org/article/ce235e57c3334e8584b6bcb64b10b27e
Autor:
Joshua M. Baughman, Christopher M. Rose, Ganesh Kolumam, Joshua D. Webster, Emily M. Wilkerson, Anna E. Merrill, Timothy W. Rhoads, Rajkumar Noubade, Paula Katavolos, Justin Lesch, Donald S. Stapleton, Mary E. Rabaglia, Kathy L. Schueler, Raymond Asuncion, Melanie Domeyer, Jose Zavala-Solorio, Michael Reich, Jason DeVoss, Mark P. Keller, Alan D. Attie, Alexander S. Hebert, Michael S. Westphall, Joshua J. Coon, Donald S. Kirkpatrick, Anwesha Dey
Publikováno v:
Cell Reports, Vol 16, Iss 2, Pp 583-595 (2016)
We introduce neutron-encoded (NeuCode) amino acid labeling of mice as a strategy for multiplexed proteomic analysis in vivo. Using NeuCode, we characterize an inducible knockout mouse model of Bap1, a tumor suppressor and deubiquitinase whose in vivo
Externí odkaz:
https://doaj.org/article/8cdbcd1118fe43d0a32e0e75203ce3e3
Autor:
Ganesh Kolumam, Mark Z. Chen, Raymond Tong, Jose Zavala-Solorio, Lance Kates, Nicholas van Bruggen, Jed Ross, Shelby K. Wyatt, Vineela D. Gandham, Richard A.D. Carano, Diana Ronai Dunshee, Ai-Luen Wu, Benjamin Haley, Keith Anderson, Søren Warming, Xin Y. Rairdan, Nicholas Lewin-Koh, Yingnan Zhang, Johnny Gutierrez, Amos Baruch, Thomas R. Gelzleichter, Dale Stevens, Sharmila Rajan, Travis W. Bainbridge, Jean-Michel Vernes, Y. Gloria Meng, James Ziai, Robert H. Soriano, Matthew J. Brauer, Yongmei Chen, Scott Stawicki, Hok Seon Kim, Laëtitia Comps-Agrar, Elizabeth Luis, Christoph Spiess, Yan Wu, James A. Ernst, Owen P. McGuinness, Andrew S. Peterson, Junichiro Sonoda
Publikováno v:
EBioMedicine, Vol 2, Iss 7, Pp 730-743 (2015)
Dissipating excess calories as heat through therapeutic stimulation of brown adipose tissues (BAT) has been proposed as a potential treatment for obesity-linked disorders. Here, we describe the generation of a humanized effector-less bispecific antib
Externí odkaz:
https://doaj.org/article/acbf9281cbc1473db78d9eaceadaf5d7
Autor:
Mark J. Solloway, Azadeh Madjidi, Chunyan Gu, Jeff Eastham-Anderson, Holly J. Clarke, Noelyn Kljavin, Jose Zavala-Solorio, Lance Kates, Brad Friedman, Matt Brauer, Jianyong Wang, Oliver Fiehn, Ganesh Kolumam, Howard Stern, John B. Lowe, Andrew S. Peterson, Bernard B. Allan
Publikováno v:
Cell Reports, Vol 12, Iss 3, Pp 495-510 (2015)
Understanding the regulation of islet cell mass has important implications for the discovery of regenerative therapies for diabetes. The liver plays a central role in metabolism and the regulation of endocrine cell number, but liver-derived factors t
Externí odkaz:
https://doaj.org/article/163b2ab582494158b0ccab448ca4c97b
Autor:
Ganesh Kolumam, Xiumin Wu, Wyne P Lee, Jason A Hackney, Jose Zavala-Solorio, Vineela Gandham, Dimitry M Danilenko, Puneet Arora, Xiaoting Wang, Wenjun Ouyang
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170639 (2017)
Diabetic foot ulcers (DFU) are one of the major complications in type II diabetes patients and can result in amputation and morbidity. Although multiple approaches are used clinically to help wound closure, many patients still lack adequate treatment
Externí odkaz:
https://doaj.org/article/12da7ac249cf4cd88459569faf61f85e
Autor:
Ai-Luen Wu, Bo Feng, Mark Z Chen, Ganesh Kolumam, Jose Zavala-Solorio, Shelby K Wyatt, Vineela D Gandham, Richard A D Carano, Junichiro Sonoda
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57322 (2013)
The phosphaturic hormone Fibroblast Growth Factor 23 (FGF23) controls phosphate homeostasis by regulating renal expression of sodium-dependent phosphate co-transporters and cytochrome P450 enzymes involved in vitamin D catabolism. Multiple FGF Recept
Externí odkaz:
https://doaj.org/article/7746b2c7b71048fbbf201ac0ccb024f6
Akademický článek
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Autor:
Adam M Speen, Jessica R Murray, Quentin Todd Krantz, David Davies, Paul Evansky, Joshua A Harrill, Logan J Everett, Joseph L Bundy, Lisa A Dailey, Jazzlyn Hill, Wyatt Zander, Elise Carlsten, Michael Monsees, Jose Zavala, Mark A Higuchi
Publikováno v:
Toxicol Sci
Inhalation is the most relevant route of volatile organic chemical (VOC) exposure; however, due to unique challenges posed by their chemical properties and poor solubility in aqueous solutions, in vitro chemical safety testing is predominantly perfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e53d729c9340cdc51b5aac6c9ddfbf9e
https://doi.org/10.1093/toxsci/kfac040
https://doi.org/10.1093/toxsci/kfac040
Autor:
Aleksandr Gaun, Magdalena Preciado López, Niclas Olsson, John C.K. Wang, Leanne J.G. Chan, Jonathon O'Brien, Wenzhou Li, Jose Zavala‐Solorio, Chunlian Zhang, Dan Eaton, Fiona E McAllister
Publikováno v:
ProteomicsREFERENCES. 22(19-20)
Systemic lupus erythematosus is a common autoimmune inflammatory disease which is associated with increases in autoantibodies and immune complexes that deposit in the kidney. The MRL-lpr mouse is a common mouse model used for the study of lupus and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dc6548d52f1670187e7a066b7a1873c
https://pubmed.ncbi.nlm.nih.gov/35964289
https://pubmed.ncbi.nlm.nih.gov/35964289