Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jose Zapardiel-Gonzalo"'
Autor:
Peter Achenbach, Markus Hippich, Jose Zapardiel-Gonzalo, Beate Karges, Reinhard W. Holl, Agnese Petrera, Ezio Bonifacio, Anette-G. Ziegler
Publikováno v:
EBioMedicine, Vol 82, Iss , Pp 104118- (2022)
Summary: Background: Diabetes in childhood and adolescence includes autoimmune and non-autoimmune forms with heterogeneity in clinical and biochemical presentations. An unresolved question is whether there are subtypes, endotypes, or theratypes withi
Externí odkaz:
https://doaj.org/article/44c3c10a8be74adfad637a8c2b3650fc
Autor:
Yuan Tian, Mariana Babor, Jerome Lane, Veronique Schulten, Veena S. Patil, Grégory Seumois, Sandy L. Rosales, Zheng Fu, Gaelle Picarda, Julie Burel, Jose Zapardiel-Gonzalo, Rashika N. Tennekoon, Aruna D. De Silva, Sunil Premawansa, Gayani Premawansa, Ananda Wijewickrama, Jason A. Greenbaum, Pandurangan Vijayanand, Daniela Weiskopf, Alessandro Sette, Bjoern Peters
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Memory T cells are essential for combating recurring infection by promoting prompt and effective immune responses. Here the authors show, via system biology approaches, that human CD4 memory T cells contains a CD45RA-rexpressing pool that can be furt
Externí odkaz:
https://doaj.org/article/1300a213373847c1bd139605b64d5245
Publikováno v:
Diabetologia. 66:1129-1141
Aims/hypothesis Insulitis is not present in all islets, and it is elusive in humans. Although earlier studies focused on islets that fulfilled certain criteria (e.g. ≥15 CD45+ cells or ≥6 CD3+ cells), there is a fundamental lack of understanding
Autor:
Elisabeth Huber, Kerstin Kick, Melanie Bunk, Mayscha Hebel, Andreas Weiß, Benjamin Marcus, Jose Zapardiel Gonzalo, Peter Achenbach, Anette-Gabriele Ziegler
Publikováno v:
Diabetologie und Stoffwechsel.
BackgroundGene network inference (GNI) methods have the potential to reveal functional relationships between different genes and their products. Most GNI algorithms have been developed for microarray gene expression datasets and their application to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f405b29b0e8242ca34504bd6d074868
https://doi.org/10.1101/2023.01.02.522518
https://doi.org/10.1101/2023.01.02.522518
Autor:
Andreas, Weiss, Jose, Zapardiel-Gonzalo, Franziska, Voss, Manja, Jolink, Joanna, Stock, Florian, Haupt, Kerstin, Kick, Tiziana, Welzhofer, Anja, Heublein, Christiane, Winkler, Peter, Achenbach, Anette-Gabriele, Ziegler, Ezio, Bonifacio
Publikováno v:
Diabetologia 65, 93-104 (2022)
Aims/hypothesis The aim of this study was to develop strategies that identify children from the general population who have late-stage presymptomatic type 1 diabetes and may, therefore, benefit from immune intervention. Methods We tested children fro
Autor:
Vito Lampasona, Philipp Sifft, Markus Hippich, Jose Zapardiel-Gonzalo, Anette G. Ziegler, Merle M Böhmer, Ezio Bonifacio
Publikováno v:
Med (New York, N.y.)
Hippich et al update their surveillance of SARS-CoV-2 antibodies in the Bavarian childhood population and show an eight-fold prevalence increase during 2021 as compared to the end of first wave in 2020. Over 50% of positive children were asymptomatic
Autor:
Ivan C. Gerling, Sarah J. Richardson, Teresa Rodriguez-Calvo, Pouria Akhbari, Paola S. Apaolaza, Nataliya I. Lenchik, Jose Zapardiel-Gonzalo, Grace Nelson, Diana Balcacean
Publikováno v:
Science Advances
Sci. Adv. 7:eabd6527 (2021)
Sci. Adv. 7:eabd6527 (2021)
Interferon response sensors are expressed in the islet of Langerhans during the course of type 1 diabetes.
Previous results indicate the presence of an interferon (IFN) signature in type 1 diabetes (T1D), capable of inducing chronic inflammation
Previous results indicate the presence of an interferon (IFN) signature in type 1 diabetes (T1D), capable of inducing chronic inflammation
Autor:
Joseph F. Petrosino, Jan Knoop, Robin Assfalg, Ezio Bonifacio, Andreas Weiss, Peter Achenbach, Kristi L. Hoffman, Melanie Bunk, Anne Eugster, Jörg Hasford, Markus Pfirrmann, Anette-Gabriele Ziegler, Yannick F. Fuchs, Jose Zapardiel-Gonzalo, Anna Hofelich, Julia Reinhardt, Marc Weigelt, Claudia Matzke, Markus Hippich, Stefanie M. Hauck, Kathrin Halfter
BackgroundOral administration of antigen can induce immunological tolerance. Insulin is a key autoantigen in childhood type 1 diabetes with insulin autoimmunity often appearing in the first years of life. Here, oral insulin was given as antigen-speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee95dce39bd7668922f7eec2822fe580
https://doi.org/10.1101/2020.06.12.20129189
https://doi.org/10.1101/2020.06.12.20129189
Autor:
Ulrike Protzer, Peter Achenbach, Ezio Bonifacio, Susanne Heck, Merle Boehmer, Franziska Voss, Lisa Holthaus, Anette-Gabriele Ziegler, Martin Heigermoser, Tiziana C. Welzhofer, Joanna Stock, Dominik A. Ewald, F Haupt, Heidi Kapfelsperger, Lorenzo Piemonti, Benjamin A. Marcus, Markus Hippich, Annika Koelln, Jose Zapardiel-Gonzalo, Vito Lampasona, Kathrin de la Rosa, Robin Assfalg, Massimiliano Secchi
Publikováno v:
Med
Med (New York, N.y.)
Med (New York, N.y.)
Background Antibody responses to virus reflect exposure and potential protection. Methods We developed a highly specific and sensitive approach to measuring antibodies against SARS-CoV-2 for population-scale immune surveillance. Antibody positivity w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8c94b745fb5c471c6f139b74560f104