Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jose S. Possomato-Vieira"'
Autor:
Regina A. Nascimento, Jose S. Possomato-Vieira, Giselle F. Bonacio, Elen Rizzi, Carlos A. Dias-Junior
Publikováno v:
Cells, Vol 8, Iss 11, p 1402 (2019)
Hypertensive pregnancy has been associated with reduced nitric oxide (NO), bioavailability, and increased activity of matrix metalloproteinases (MMPs). However, it is unclear if MMPs activation is regulated by NO during pregnancy. To this end, we exa
Externí odkaz:
https://doaj.org/article/a83f1aa7c29f441fb79544717492a22c
Autor:
Carlos A. Dias-Junior, Ning Cui, Juanjuan Chen, Raouf A. Khalil, Charles L. Chiang, Zongli Ren, Minglin Zhu, Jose S. Possomato-Vieira
Publikováno v:
Biochemical Pharmacology. 146:101-116
Preeclampsia is a form of hypertension-in-pregnancy (HTN-Preg) with unclear mechanism. Generalized reduction of uterine perfusion pressure (RUPP) could be an initiating event leading to uteroplacental ischemia, angiogenic imbalance, and HTN-Preg. Add
Autor:
Raouf A. Khalil, Helen Christou, Jun Li, Hannes Hudalla, Carlos A. Dias-Junior, Minglin Zhu, Evgenia J. Filatava, Jose S. Possomato-Vieira, Stella Kourembanas, Zoe Michael
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 364(2)
Pulmonary vasoreactivity could determine the responsiveness to vasodilators and, in turn, the prognosis of pulmonary hypertension (PH). We hypothesized that pulmonary vasoreactivity is impaired, and we examined the underlying mechanisms in the Sugen-
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 311(3)
Preeclampsia (PE) is a pregnancy-related hypertensive disorder (HTN-Preg) with unclear mechanism. An imbalance between antiangiogenic soluble fms-like tyrosine kinase-1 (sFlt-1) and angiogenic placental growth factor (PlGF) has been observed in PE, b
Preeclampsia is a pregnancy-related disorder characterized by hypertension and could lead to maternal and fetal morbidity and mortality. Although the causative factors and pathophysiological mechanisms are unclear, endothelial dysfunction is a major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bcc24ff2e6cc4eb3248278624512d7d
https://doi.org/10.1016/bs.apha.2016.04.008
https://doi.org/10.1016/bs.apha.2016.04.008
Publikováno v:
Hypertension. 66
Preeclampsia is a pregnancy-related hypertensive disorder (HTN-Preg) with an imbalance between anti-angiogenic soluble fms-like tyrosine kinase-1 (sFlt-1) and angiogenic PlGF, but the vascular targets involved are unclear. We have shown downregulatio