Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jose Rodriguez-Santana"'
Autor:
Jamie L. Everman, Satria P. Sajuthi, Maude A. Liegeois, Nathan D. Jackson, Erik H. Collet, Michael C. Peters, Maurizio Chioccioli, Camille M. Moore, Bhavika B. Patel, Nathan Dyjack, Roger Powell, Cydney Rios, Michael T. Montgomery, Celeste Eng, Jennifer R. Elhawary, Angel C. Y. Mak, Donglei Hu, Scott Huntsman, Sandra Salazar, Luigi Feriani, Ana Fairbanks-Mahnke, Gianna L. Zinnen, Cole R. Michel, Joe Gomez, Xing Zhang, Vivian Medina, Hong Wei Chu, Pietro Cicuta, Erin D. Gordon, Pamela Zeitlin, Victor E. Ortega, Nichole Reisdorph, Eleanor M. Dunican, Monica Tang, Brett M. Elicker, Travis S. Henry, Eugene R. Bleecker, Mario Castro, Serpil C. Erzurum, Elliot Israel, Bruce D. Levy, David T. Mauger, Deborah A. Meyers, Kaharu Sumino, David S. Gierada, Annette T. Hastie, Wendy C. Moore, Loren C. Denlinger, Nizar N. Jarjour, Mark L. Schiebler, Sally E. Wenzel, Prescott G. Woodruff, Jose Rodriguez-Santana, Chad G. Pearson, Esteban G. Burchard, John V. Fahy, Max A. Seibold
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract By incompletely understood mechanisms, type 2 (T2) inflammation present in the airways of severe asthmatics drives the formation of pathologic mucus which leads to airway mucus plugging. Here we investigate the molecular role and clinical si
Externí odkaz:
https://doaj.org/article/e5fbd453726447a6a3e42371a05beeb5
Autor:
Satria P. Sajuthi, Peter DeFord, Yingchun Li, Nathan D. Jackson, Michael T. Montgomery, Jamie L. Everman, Cydney L. Rios, Elmar Pruesse, James D. Nolin, Elizabeth G. Plender, Michael E. Wechsler, Angel C. Y. Mak, Celeste Eng, Sandra Salazar, Vivian Medina, Eric M. Wohlford, Scott Huntsman, Deborah A. Nickerson, Soren Germer, Michael C. Zody, Gonçalo Abecasis, Hyun Min Kang, Kenneth M. Rice, Rajesh Kumar, Sam Oh, Jose Rodriguez-Santana, Esteban G. Burchard, Max A. Seibold
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
ACE2 and TMPRSS2 have received recent attention as entry factors for SARS-CoV-2. Here the authors analyze nasal airway transcriptome data from 695 children determining ACE2 and TMPRSS2 expression is induced by viral and type2 inflammation, respective
Externí odkaz:
https://doaj.org/article/5998991851af4757adcf82673111f6e4
Autor:
Agata Wesolowska-Andersen, Jamie L. Everman, Rebecca Davidson, Cydney Rios, Rachelle Herrin, Celeste Eng, William J. Janssen, Andrew H. Liu, Sam S. Oh, Rajesh Kumar, Tasha E. Fingerlin, Jose Rodriguez-Santana, Esteban G. Burchard, Max A. Seibold
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-17 (2017)
Abstract Background Respiratory illness caused by viral infection is associated with the development and exacerbation of childhood asthma. Little is known about the effects of respiratory viral infections in the absence of illness. Using quantitative
Externí odkaz:
https://doaj.org/article/f49dee92afad46829bbfda924b782b65
Autor:
Agata Wesolowska-Andersen, Jamie L. Everman, Rebecca Davidson, Cydney Rios, Rachelle Herrin, Celeste Eng, William J. Janssen, Andrew H. Liu, Sam S. Oh, Rajesh Kumar, Tasha E. Fingerlin, Jose Rodriguez-Santana, Esteban G. Burchard, Max A. Seibold
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-1 (2018)
Abstract In our recent article [1], it has come to our attention that the sample labels are not consistent between Table 1, the data labels deposited in the Sequence Read Archive, and Additional file 1: Table S2. We are therefore providing an updated
Externí odkaz:
https://doaj.org/article/9da866b737dd43d3bdfcc850807b82ac
Autor:
Catarina D Campbell, Kiana Mohajeri, Maika Malig, Fereydoun Hormozdiari, Benjamin Nelson, Gaixin Du, Kristen M Patterson, Celeste Eng, Dara G Torgerson, Donglei Hu, Catherine Herman, Jessica X Chong, Arthur Ko, Brian J O'Roak, Niklas Krumm, Laura Vives, Choli Lee, Lindsey A Roth, William Rodriguez-Cintron, Jose Rodriguez-Santana, Emerita Brigino-Buenaventura, Adam Davis, Kelley Meade, Michael A LeNoir, Shannon Thyne, Daniel J Jackson, James E Gern, Robert F Lemanske, Jay Shendure, Mark Abney, Esteban G Burchard, Carole Ober, Evan E Eichler
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104396 (2014)
Asthma is a complex genetic disease caused by a combination of genetic and environmental risk factors. We sought to test classes of genetic variants largely missed by genome-wide association studies (GWAS), including copy number variants (CNVs) and l
Externí odkaz:
https://doaj.org/article/98e7e72d10cd4b5ca2e3cbed7c9bd96a
Multi-omic approach associates blood methylome with bronchodilator drug response in pediatric asthma
Autor:
Javier Perez-Garcia, Esther Herrera-Luis, Annie Li, Angel C.Y. Mak, Scott Huntsman, Sam S. Oh, Jennifer R. Elhawary, Celeste Eng, Kenneth B. Beckman, Donglei Hu, Fabian Lorenzo-Diaz, Michael A. Lenoir, Jose Rodriguez-Santana, Noah Zaitlen, Jesús Villar, Luisa N. Borrell, Esteban G. Burchard, Maria Pino-Yanes
Publikováno v:
Journal of Allergy and Clinical Immunology.
Autor:
Esther Herrera-Luis, Annie Li, Angel C. Y. Mak, Javier Perez-Garcia, Jennifer R. Elhawary, Sam S. Oh, Donglei Hu, Celeste Eng, Kevin L. Keys, Scott Huntsman, Kenneth B. Beckman, Luisa N. Borrell, Jose Rodriguez-Santana, Esteban G. Burchard, Maria Pino-Yanes
Publikováno v:
Clinical Epigenetics
Clinical epigenetics, vol 14, iss 1
Clinical epigenetics, vol 14, iss 1
Introduction DNA methylation studies have associated methylation levels at different CpG sites or genomic regions with lung function. Moreover, genetic ancestry has been associated with lung function in Latinos. However, no epigenome-wide association
Autor:
Javier Perez-Garcia, Maria Pino-Yanes, Elizabeth G. Plender, Jamie L. Everman, Celeste Eng, Nathan D. Jackson, Camille M. Moore, Kenneth B. Beckman, Vivian Medina, Sunita Sharma, Daniel Efrain Winnica, Fernando Holguin, José Rodríguez-Santana, Jesús Villar, Elad Ziv, Max A. Seibold, Esteban G. Burchard
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-16 (2023)
Abstract Background Albuterol is the first-line asthma medication used in diverse populations. Although DNA methylation (DNAm) is an epigenetic mechanism involved in asthma and bronchodilator drug response (BDR), no study has assessed whether albuter
Externí odkaz:
https://doaj.org/article/dd94221e29c147b18ed997f3b41be0f7
Autor:
Cydney Rios, Hagit T. Porath, Timothy Daley, Max A. Seibold, Serghei Mangul, Andrew D. Smith, Prescott G. Woodruff, Kevin Hsieh, Jose Rodriguez Santana, Celeste Eng, Harry Taegyun Yang, Nicolas Strauli, Agata Wesolowska-Andersen, Esteban G. Burchard, Eleazar Eskin, Sagiv Shifman, Linus Chen, Stephanie A. Christenson, Franziska Gruhl, Erez Y. Levanon, Roberto Spreafico, Roel A. Ophoff, Ryan D. Hernandez, Noah Zaitlen
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-12 (2018)
Genome biology, vol 19, iss 1
Genome Biology, vol. 19, no. 1, pp. 36
Genome Biology
Genome biology, vol 19, iss 1
Genome Biology, vol. 19, no. 1, pp. 36
Genome Biology
High-throughput RNA-sequencing (RNA-seq) technologies provide an unprecedented opportunity to explore the individual transcriptome. Unmapped reads are a large and often overlooked output of standard RNA-seq analyses. Here, we present Read Origin Prot
Autor:
Satria P. Sajuthi, Jamie L. Everman, Nathan D. Jackson, Benjamin Saef, Cydney L. Rios, Camille M. Moore, Angel C. Y. Mak, Celeste Eng, Ana Fairbanks–Mahnke, Sandra Salazar, Jennifer Elhawary, Scott Huntsman, Vivian Medina, Deborah A. Nickerson, Soren Germer, Michael C. Zody, Gonçalo Abecasis, Hyun Min Kang, Kenneth M. Rice, Rajesh Kumar, Noah A. Zaitlen, Sam Oh, NHLBI Trans–Omics for Precision Medicine (TOPMed) Consortium, José Rodríguez–Santana, Esteban G. Burchard, Max A. Seibold
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Externí odkaz:
https://doaj.org/article/2becd8c53e824b738a9f10d4fbec7c85