Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jose Renato, Pinto"'
Autor:
Taejeong Song, Maicon Landim-Vieira, Mustafa Ozdemir, Caroline Gott, Onur Kanisicak, Jose Renato Pinto, Sakthivel Sadayappan
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 3, Pp 502-509 (2023)
Muscle disease: understanding different forms of a key muscle protein Contraction and relaxation of both heart and skeletal muscles are regulated by different forms of a protein called MyBP-C, mutations in this protein being important causes of heart
Externí odkaz:
https://doaj.org/article/ae49ecf09d0548ee978281c8c2b8759f
Autor:
Steven Marston, Jose Renato Pinto
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2023)
In cardiac muscle the action of adrenaline on β1 receptors of heart muscle cells is essential to adjust cardiac output to the body’s needs. Adrenergic activation leads to enhanced contractility (inotropy), faster heart rate (chronotropy) and faste
Externí odkaz:
https://doaj.org/article/9fca58cdcc864f24a93439b01119edc7
Autor:
Maicon Landim-Vieira, Jamie R. Johnston, Weizhen Ji, Emily K. Mis, Joshua Tijerino, Michele Spencer-Manzon, Lauren Jeffries, E. Kevin Hall, David Panisello-Manterola, Mustafa K. Khokha, Engin Deniz, P. Bryant Chase, Saquib A. Lakhani, Jose Renato Pinto
Publikováno v:
Frontiers in Physiology, Vol 10 (2020)
Familial dilated cardiomyopathy (DCM), clinically characterized by enlargement and dysfunction of one or both ventricles of the heart, can be caused by variants in sarcomeric genes including TNNC1 (encoding cardiac troponin C, cTnC). Here, we report
Externí odkaz:
https://doaj.org/article/d54c1495d9574db285c1dbf940168414
Autor:
Steven Marston, Jose Renato Pinto
In cardiac muscle the action of adrenaline on β1 receptors of heart muscle cells is essential to adjust cardiac output to the body’s needs. Adrenergic activation leads to enhanced contractility (inotropy), faster heart rate (chronotropy) and faste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d6a29abe1880e69b442d01d89b3426a
http://hdl.handle.net/10044/1/102631
http://hdl.handle.net/10044/1/102631
Publikováno v:
Frontiers in Physiology, Vol 5 (2014)
The potential alterations to structure and associations with thin filament proteins caused by the dilated cardiomyopathy (DCM) associated tropomyosin (Tm) mutants E40K and E54K, and the hypertrophic cardiomyopathy (HCM) associated Tm mutants E62Q and
Externí odkaz:
https://doaj.org/article/6d53adef779745fead6917f6faabfa23
Autor:
Karissa M, Dieseldorff Jones, Yeojung, Koh, Rebecca S, Weller, Rajdeep S, Turna, Ferhaan, Ahmad, Sabine, Huke, Björn C, Knollmann, Jose Renato, Pinto, Hyun Seok, Hwang
Publikováno v:
Archives of biochemistry and biophysics. 661
Mutations in cardiac troponin T (TnT) associated with hypertrophic cardiomyopathy generally lead to an increase in the Ca(2+) sensitivity of contraction and susceptibility to arrhythmias. In contrast, TnT mutations linked to dilated cardiomyopathy de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ddea603e28d838c9c018e285ed539e0
https://pubmed.ncbi.nlm.nih.gov/30445044
https://pubmed.ncbi.nlm.nih.gov/30445044
Autor:
Jose Renato, Pinto, Shi Wei, Yang, Marc-Phillip, Hitz, Michelle S, Parvatiyar, Michelle A, Jones, Jingsheng, Liang, Victor, Kokta, Mario, Talajic, Nicolas, Tremblay, Michelle, Jaeggi, Gregor, Andelfinger, James D, Potter
Publikováno v:
The Journal of biological chemistry. 286(23)
A novel double deletion in cardiac troponin T (cTnT) of two highly conserved amino acids (Asn-100 and Glu-101) was found in a restrictive cardiomyopathic (RCM) pediatric patient. Clinical evaluation revealed the presence of left atrial enlargement an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ecfd7b5178500db2bee1b445b0b1b4ed
https://pubmed.ncbi.nlm.nih.gov/21502316
https://pubmed.ncbi.nlm.nih.gov/21502316
Autor:
Jose Renato, Pinto, Daniel P, Reynaldo, Michelle S, Parvatiyar, David, Dweck, Jingsheng, Liang, Michelle A, Jones, Martha M, Sorenson, James D, Potter
Publikováno v:
The Journal of biological chemistry. 286(2)
This spectroscopic study examined the steady-state and kinetic parameters governing the cross-bridge effect on the increased Ca(2+) affinity of hypertrophic cardiomyopathy-cardiac troponin C (HCM-cTnC) mutants. Previously, we found that incorporation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5cf52b898b411596d889b225894bf78
https://pubmed.ncbi.nlm.nih.gov/21056975
https://pubmed.ncbi.nlm.nih.gov/21056975