Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jose R. Tormos"'
Publikováno v:
Chemico-Biological Interactions. 187:124-127
beta-Secondary deuterium isotope effects have been measured for equine serum butyrylcholinesterase-catalyzed hydrolysis of acetyl-L(3)-thiocholine (L=H or (2)H). The dependencies of initial rates on isotopic substrate concentrations show close adhere
Autor:
Florian Nachon, Jose R. Tormos, Patrick Masson, Yi Wang, Kenneth L. Wiley, Daniel M. Quinn, Didier Fournier
Publikováno v:
Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2010, 132 (50), pp.17751-17759. ⟨10.1021/ja104496q⟩
Journal of the American Chemical Society, American Chemical Society, 2010, 132 (50), pp.17751-17759. ⟨10.1021/ja104496q⟩
Contact: daniel-quinn@uiowa.edu; International audience; In a previous communication, kinetic beta-deuterium secondary isotope effects were reported that support a mechanism for substrate-activated turnover of acetylthiocholine by human butyrylcholin
Autor:
Daniel M. Quinn, Javier Seravalli, Patrick Masson, Yvain Nicolet, Jose R. Tormos, Florian Nachon, Kenneth L. Wiley
Publikováno v:
Journal of the American Chemical Society. 127(42)
Secondary beta-deuterium kinetic isotope effects have been measured as a function of substrate concentration for recombinant human butyrylcholinesterase-catalyzed hydrolysis of acetyl-L3-thiocholine (L = 1H or 2H). The isotope effect on V/K is invers