Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jose Palbo Leone"'
Autor:
Jing Ni, Sheheryar Kabraji, Shaozhen Xie, Yanzhi Wang, Peichen Pan, Xiaofang He, Zongming Liu, Jose Palbo Leone, Henry W. Long, Myles A. Brown, Eric P. Winer, Deborah A. R. Dillon, Nancy U. Lin, Jean J. Zhao
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
HER2+ breast cancer often develop brain metastases (BCBMs) that are difficult to treat. Here, the authors show that p16INK4A loss in BCBMs from HER2+ breast tumors results in resistance to the HER2 inhibitor Tucatinib, and that CDK4/6 inhibition can
Externí odkaz:
https://doaj.org/article/16bc242049ff4c6ca1e0501ace504822
Autor:
Jing, Ni, Sheheryar, Kabraji, Shaozhen, Xie, Yanzhi, Wang, Peichen, Pan, Xiaofang, He, Zongming, Liu, Jose Palbo, Leone, Henry W, Long, Myles A, Brown, Eric P, Winer, Deborah A R, Dillon, Nancy U, Lin, Jean J, Zhao
Publikováno v:
Nature communications. 13(1)
Approximately 50% of patients with metastatic HER2-positive (HER2+) breast cancer develop brain metastases (BCBMs). We report that the tumor suppressor p16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::15b0ff92c3762d7498bc19e21519a704
https://pubmed.ncbi.nlm.nih.gov/35304445
https://pubmed.ncbi.nlm.nih.gov/35304445