Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jose Olucha"'
Publikováno v:
Biochemistry. 51:7525-7532
PchB is an isochorismate-pyruvate lyase from Pseudomonas aeruginosa. A positively charged lysine residue is located in a flexible loop that behaves as a lid to the active site, and the lysine residue is required for efficient production of salicylate
Autor:
Jose Olucha, Audrey L. Lamb
Publikováno v:
Bioorganic Chemistry. 39:171-177
The N-hydroxylating flavoprotein monooxygenases are siderophore biosynthetic enzymes that catalyze the hydroxylation of the sidechain amino-group of ornithine or lysine or the primary amino-group of putrescine. This hydroxylated product is subsequent
Publikováno v:
Journal of Biological Chemistry. 286:31789-31798
The ornithine hydroxylase from Pseudomonas aeruginosa (PvdA) catalyzes the FAD-dependent hydroxylation of the side chain amine of ornithine, which is subsequently formylated to generate the iron-chelating hydroxamates of the siderophore pyoverdin. Pv
Publikováno v:
Biochemistry. 48:5239-5245
The isochorismate-pyruvate lyase from Pseudomonas aeruginosa (PchB) catalyzes two pericyclic reactions in a single active site. PchB physiologically produces salicylate and pyruvate from isochorismate for ultimate incorporation of the salicylate into
Autor:
Hugh Rosen, Steven J. Brown, Bruno E. Correia, Kenneth M. Lum, Armand B. Cognetta, Taka-Aki Ichu, Fabiana Piscitelli, Jose Olucha, Soumajit Kundu, Benjamin F. Cravatt, Micah J. Niphakis
Publikováno v:
Cell (Cambridge) 161 (2015): 1668–1680. doi:10.1016/j.cell.2015.05.045
info:cnr-pdr/source/autori:Niphakis, Micah J.; Lum, Kenneth M.; Cognetta, Armand B., III; Correia, Bruno E.; Ichu, Taka-Aki; Olucha, Jose; Brown, Steven J.; Kundu, Soumajit; Piscitelli, Fabiana; Rosen, Hugh; Cravatt, Benjamin F./titolo:A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells/doi:10.1016%2Fj.cell.2015.05.045/rivista:Cell (Cambridge)/anno:2015/pagina_da:1668/pagina_a:1680/intervallo_pagine:1668–1680/volume:161
info:cnr-pdr/source/autori:Niphakis, Micah J.; Lum, Kenneth M.; Cognetta, Armand B., III; Correia, Bruno E.; Ichu, Taka-Aki; Olucha, Jose; Brown, Steven J.; Kundu, Soumajit; Piscitelli, Fabiana; Rosen, Hugh; Cravatt, Benjamin F./titolo:A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells/doi:10.1016%2Fj.cell.2015.05.045/rivista:Cell (Cambridge)/anno:2015/pagina_da:1668/pagina_a:1680/intervallo_pagine:1668–1680/volume:161
SummaryLipids play central roles in physiology and disease, where their structural, metabolic, and signaling functions often arise from interactions with proteins. Here, we describe a set of lipid-based chemical proteomic probes and their global inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7701d83be528fb04eb86cd74c103b066
https://europepmc.org/articles/PMC4615699/
https://europepmc.org/articles/PMC4615699/
Autor:
Ping Jiang, Enrique Saez, Benjamin D. Horning, Radu M. Suciu, Esther K. Kemper, Thomas A Paul, Keriann M. Backus, Jose Olucha, Liron Bar-Peled, Melissa M. Dix, Reuben J. Shaw, Taka-Aki Ichu, Matthew Merrill Hayward, Bernard P. Kok, Ekaterina V. Vinogradova, Nathan T. Ihle, Zhou Zhu, Max W. Chang, Robert U. Svensson, Benjamin F. Cravatt
Publikováno v:
Cell. 171:696-709.e23
The transcription factor NRF2 is a master regulator of the cellular antioxidant response, and it is often genetically activated in non-small-cell lung cancers (NSCLCs) by, for instance, mutations in the negative regulator KEAP1. While direct pharmaco
An isochorismate-pyruvate lyase with adventitious chorismate mutase activity from Pseudomonas aerugionsa (PchB) achieves catalysis of both pericyclic reactions in part by the stabilization of reactive conformations and in part by electrostatic transi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a811fa2526ecd12c95092d3633383e8
https://europepmc.org/articles/PMC3156872/
https://europepmc.org/articles/PMC3156872/
Publikováno v:
Acta Crystallographica: Section F, Structural Biology Communications; Oct2014, Vol. 70 Issue 10, p1328-1332, 5p
Más allá de los estudios genealógicos, la historiografía sobre la nobleza española ha ofrecido un panorama bastante limitado hasta hace bien poco. En el caso valenciano ha sido recientemente cuando se ha concebido la idea de abordar un tema tan
Autor:
Vicent Gabarda Cebellán
Si partim de l'anàlisi detallada de la secció de defuncions del Registre Civil podem conèixer amb exhaustivitat quantes persones va afectar la repressió franquista fins a les últimes conseqüències: l'afusellament davant un escamot d'execució.