Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jose O. Esteves-Villanueva"'
Publikováno v:
Canadian Journal of Chemistry. 99:628-636
Metal ion dyshomeostasis plays an important role in diseases, including neurodegeneration. Tau protein is a known neurodegeneration biomarker, but its interactions with biologically relevant metal ions, such as Cu(II), are not fully understood. Herei
Publikováno v:
Analytical Biochemistry. 496:55-62
Tau protein hyperphosphorylation triggers tau aggregation and its toxicity, leading to neuronal death and cell-to-cell toxicity. Hence, inhibition of protein kinases is a viable tool toward reduction of tau toxicity. By targeting various epitopes of
Publikováno v:
Electrochimica Acta. 162:24-30
The tau protein is a neurodegenerative disease biomarker. The in vitro aggregation of tau is triggered by electrostatic charge imbalance induced by an anionic inducing agent, such as heparin. The binding of the tau-heparin complex is based on electro
Publikováno v:
The Analyst. 139:2823-2831
A protein-based electrochemical biosensor was developed for detection of tau protein aimed towards electrochemically sensing misfolding proteins. The electrochemical assay monitors tau-tau binding and misfolding during the early stage of tau oligomer
Publikováno v:
Journal of inorganic biochemistry. 162
Tau protein is a neurodegeneration biomarker. Due to the high concentration of metal ions in the brain, the metallation of tau proteins and their catalytic role in reactive oxygen formation have been identified as a major biochemical pathway of neuro
Autor:
Sanela Martic-Milne, Kamaljit Kaur, Jose O. Esteves-Villanueva, Hanna Trzeciakiewicz, Rania Soudy
Publikováno v:
Sensors
Volume 15
Issue 8
Pages 19429-19442
Sensors (Basel, Switzerland)
Sensors, Vol 15, Iss 8, Pp 19429-19442 (2015)
Volume 15
Issue 8
Pages 19429-19442
Sensors (Basel, Switzerland)
Sensors, Vol 15, Iss 8, Pp 19429-19442 (2015)
The adsorption of the proteins CD13, mucin and bovine serum albumin on VLGXE-Au and YNGRT-Au interfaces was monitored by electrochemical impedance spectroscopy in the presence of [Fe(CN)6](3-/4-). The hydrophobicity of the Au surface was tailored usi
Publikováno v:
ECS Meeting Abstracts. :1472-1472
not Available.