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of 176
pro vyhledávání: '"Jose N. Onuchic"'
Akademický článek
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Autor:
Downey, Philip
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2010 Jul 01. 107(27), 12066-12067.
Externí odkaz:
https://www.jstor.org/stable/20724203
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Publikováno v:
eLife, Vol 10 (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly contagious, and transmission involves a series of processes that may be targeted by vaccines and therapeutics. During transmission, host cell invasion is controlled by a large-sca
Externí odkaz:
https://doaj.org/article/3161795eb02549d0b7f31b0bdc720ca8
Autor:
Ryan R Cheng, Vinicius G Contessoto, Erez Lieberman Aiden, Peter G Wolynes, Michele Di Pierro, Jose N Onuchic
Publikováno v:
eLife, Vol 9 (2020)
Using computer simulations, we generate cell-specific 3D chromosomal structures and compare them to recently published chromatin structures obtained through microscopy. We demonstrate using machine learning and polymer physics simulations that epigen
Externí odkaz:
https://doaj.org/article/dcd8f4691c724d23a58e834aec515630
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 3, p e1005456 (2017)
One of the most important roles of cells is performing their cellular tasks properly for survival. Cells usually achieve robust functionality, for example, cell-fate decision-making and signal transduction, through multiple layers of regulation invol
Externí odkaz:
https://doaj.org/article/0360172bfda54553bbb0ac02de521949
Autor:
Ola Karmi, Sarah H Holt, Luhua Song, Sagi Tamir, Yuting Luo, Fang Bai, Ammar Adenwalla, Merav Darash-Yahana, Yang-Sung Sohn, Patricia A Jennings, Rajeev K Azad, Jose' N Onuchic, Faruck Morcos, Rachel Nechushtai, Ron Mittler
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175796 (2017)
The NEET proteins mitoNEET (mNT) and nutrient-deprivation autophagy factor-1 (NAF-1) are required for cancer cell proliferation and resistance to oxidative stress. NAF-1 and mNT are also implicated in a number of other human pathologies including dia
Externí odkaz:
https://doaj.org/article/b509885fae5a481cb87866730a617cd9
Proteins are the workhorse of life. They are the building infrastructure of living systems; they are the most efficient molecular machines known, and their enzymatic activity is still unmatched in versatility by any artificial system. Perhaps protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973d69158a6050b6e25805486c5eeacb
https://zenodo.org/record/6778287
https://zenodo.org/record/6778287
Publikováno v:
F1000Research, Vol 5 (2016)
Experimentally derived structural constraints have been crucial to the implementation of computational models of biomolecular dynamics. For example, not only does crystallography provide essential starting points for molecular simulations but also hi
Externí odkaz:
https://doaj.org/article/9f03ac29b4f042c8a74f461946b0ab99
Autor:
Prakash Kulkarni, Vitor B. P. Leite, Susmita Roy, Supriyo Bhattacharyya, Atish Mohanty, Srisairam Achuthan, Divyoj Singh, Rajeswari Appadurai, Govindan Rangarajan, Keith Weninger, John Orban, Anand Srivastava, Mohit Kumar Jolly, Jose N. Onuchic, Vladimir N. Uversky, Ravi Salgia
Publikováno v:
Biophysics Reviews. 3:011306
Intrinsically disordered proteins (IDPs) are proteins that lack rigid 3D structure. Hence, they are often misconceived to present a challenge to Anfinsen's dogma. However, IDPs exist as ensembles that sample a quasi-continuum of rapidly interconverti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a02686a9c7e02dd2de4d38fd3fa880f3
https://doi.org/10.1063/5.0080512
https://doi.org/10.1063/5.0080512