Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jose Miguel Cosgaya"'
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17023 (2011)
BACKGROUND: Schwann cells (SCs) are the cell type responsible for the formation of the myelin sheath in the peripheral nervous system (PNS). As retinoic acid (RA) and other retinoids have a profound effect as regulators of the myelination program, we
Externí odkaz:
https://doaj.org/article/23688ecb841b45abb8f57f867785425f
Autor:
Núria Casals, Marta Palomo-Guerrero, Alejandro Gella, Jose Miguel Cosgaya, Carmen Grijota-Martínez
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Schwann cells (SCs) play a key role in peripheral nerve regeneration. After damage, they respond acquiring a repair phenotype that allows them to proliferate, migrate and redirect axonal growth. Previous studies have shown that Uridine-5'-Triphosphat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e97b6a26de008829da936b537a57de
https://pubmed.ncbi.nlm.nih.gov/29337237
https://pubmed.ncbi.nlm.nih.gov/29337237
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Breast cancer is one of the most lethal malignancies for women. Retinoic acid (RA) and double-stranded RNA (dsRNA) are considered signaling molecules with potential anticancer activity. RA, co-administered with the dsRNA mimic polyinosinic-polycytidy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de2cf84f1481534da58135896953562
https://pubmed.ncbi.nlm.nih.gov/28409399
https://pubmed.ncbi.nlm.nih.gov/28409399
Publikováno v:
Glia. 58:1451-1464
Understanding the mechanisms that control myelin formation is essential for the development of demyelinating diseases treatments. All-trans-retinoic acid (RA) plays an essential role during the development of the nervous system as a potent regulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8051a6b8bd30abf986085b2f4892db1c
https://doi.org/10.1002/glia.21020
https://doi.org/10.1002/glia.21020
Autor:
Ana Aranda, Jose Miguel Cosgaya
Publikováno v:
Journal of Neurochemistry. 76:661-671
Nerve growth factor (NGF) and retinoic acid (RA) exert important actions on PC12 cells. We have previously shown that incubation with NGF induces retinoic acid receptor β (RARβ) binding to a hormone response element in PC12 cells. In this study we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1305655aa98640bc468dd36f1cf1035
https://doi.org/10.1046/j.1471-4159.2001.00078.x
https://doi.org/10.1046/j.1471-4159.2001.00078.x
Autor:
Jose Miguel Cosgaya, Eric M. Shooter
Publikováno v:
Journal of Neurochemistry. 79:391-399
Nerve growth factor (NGF) regulates the activity of the transcription factor NF-κB (nuclear factor-κB) through its low affinity receptor, p75. In the present study we found that NGF binding to p75 induces nuclear translocation of p65 and increases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54be2712afdd13b5a32460cfcad2afa2
https://doi.org/10.1046/j.1471-4159.2001.00573.x
https://doi.org/10.1046/j.1471-4159.2001.00573.x
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Neurotrophins transmit signals retrogradely from synapses to cell bodies by two different types of surface receptors, p75NTR and Trks. Compared to TrkA, the function of p75NTR in nerve growth factor (NGF) endocytosis is less clear, and it is unknown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1509f5a8611b57f9b5c9677cf136d3ab
https://doi.org/10.1016/j.mcn.2004.02.006
https://doi.org/10.1016/j.mcn.2004.02.006
Autor:
Jonah R. Chan, Y.J. Wu, Alex Krüttgen, Jens Carsten Möller, Jose Miguel Cosgaya, D. Shine, Eric M. Shooter
Publikováno v:
Journal of Neuroscience Research. 75:825-834
Neurotrophins (NTs) play an important role in the modulation of synaptic transmission and in morphological changes in synaptic structures. Although there is agreement that brain-derived neurotrophic factor (BDNF) is sorted to large dense-core vesicle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1fce3ae657e5083679b5aa051e8a702
https://doi.org/10.1002/jnr.20048
https://doi.org/10.1002/jnr.20048
Publikováno v:
Science. 298:1245-1248
Schwann cells in developing and regenerating peripheral nerves express elevated levels of the neurotrophin receptor p75 NTR . Neurotrophins are key mediators of peripheral nervous system myelination. Our results show that myelin formation is inhibite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e52c6a4a1a348467e09d3ebb1ec372
https://doi.org/10.1126/science.1076595
https://doi.org/10.1126/science.1076595
Autor:
Sushama Varma, Jose Miguel Cosgaya, Y.J. Wu, Paul S. Buckmaster, C Suri, Ravi J Tolwani, Eric M. Shooter
Publikováno v:
Neuroscience. 114:795-805
There is increasing evidence that brain-derived neurotrophic factor (BDNF) modulates synaptic and morphological plasticity in the developing and mature nervous system. Plasticity may be modulated partially by BDNF's effects on dendritic structure. Ut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e7ca4935410df65ab13c18ddddee270
https://doi.org/10.1016/s0306-4522(02)00301-9
https://doi.org/10.1016/s0306-4522(02)00301-9