Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Jose Maria Moreno-Navarrete"'
Autor:
Tiago Koppe, Bonnie Patchen, Aaron Cheng, Manoj Bhasin, Chris Vulpe, Robert E. Schwartz, Jose Maria Moreno‐Navarrete, Jose Manuel Fernandez‐Real, Pavlos Pissios, Paula G. Fraenkel
Publikováno v:
Hepatology Communications, Vol 1, Iss 8, Pp 803-815 (2017)
Iron overload causes the generation of reactive oxygen species that can lead to lasting damage to the liver and other organs. The goal of this study was to identify genes that modify the toxicity of iron overload. We studied the effect of iron overlo
Externí odkaz:
https://doaj.org/article/1984d87b3c284ddf9d44de9cc56f0ec5
Autor:
Ines Soro-Arnaiz, Qilong Oscar Yang Li, Mar Torres-Capelli, Florinda Meléndez-Rodríguez, Sónia Veiga, Koen Veys, David Sebastian, Ainara Elorza, Daniel Tello, Pablo Hernansanz-Agustín, Sara Cogliati, Jose Maria Moreno-Navarrete, Eduardo Balsa, Esther Fuertes, Eduardo Romanos, Antonio Martínez-Ruiz, Jose Antonio Enriquez, Jose Manuel Fernandez-Real, Antonio Zorzano, Katrien De Bock, Julián Aragonés
Publikováno v:
Cell Reports, Vol 16, Iss 11, Pp 2991-3002 (2016)
Aging is associated with progressive white adipose tissue (WAT) enlargement initiated early in life, but the molecular mechanisms involved remain unknown. Here we show that mitochondrial complex IV (CIV) activity and assembly are already repressed in
Externí odkaz:
https://doaj.org/article/ec5bffb74faf4884a7b206fc053bc329
Autor:
Brian P Carson, Josep Maria Del Bas, Jose Maria Moreno-Navarrete, Jose Manuel Fernandez-Real, Silvia Mora
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74687 (2013)
Adiponectin is an adipokine secreted by white adipocytes involved in regulating insulin sensitivity in peripheral tissues. Secretion of adiponectin in adipocytes relies on the endosomal system, however, the intracellular machinery involved in mediati
Externí odkaz:
https://doaj.org/article/1fa1238fa0df44eabc5d0b7d169d23aa
Publikováno v:
Nutrition & Diabetes, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Background Mice experiments have underscored the efficacy of pharmacological inhibition of advanced glycation endproducts (AGEs) through the use of soluble receptors for advanced glycation endproducts (sRAGE) in mitigating obesity-linked met
Externí odkaz:
https://doaj.org/article/4ac19047d6ea42eaa66ac7451a8cb75e
Autor:
Núria Oliveras-Cañellas, Jessica Latorre, Elena Santos-González, Aina Lluch, Francisco Ortega, Jordi Mayneris-Perxachs, José-Manuel Fernández-Real, José María Moreno-Navarrete
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 166, Iss , Pp 115428- (2023)
The association among increased inflammation, disrupted iron homeostasis, and adipose tissue dysfunction in obesity has been widely recognized. However, the specific impact of inflammation on iron homeostasis during human adipogenesis and in adipocyt
Externí odkaz:
https://doaj.org/article/a15e43f200474ffdbcf610c7efb2282e
Autor:
Jessica Latorre, Ramon Díaz-Trelles, Ferran Comas, Aleix Gavaldà-Navarro, Edward Milbank, Nathalia Dragano, Samantha Morón-Ros, Rajesh Mukthavaram, Francisco Ortega, Anna Castells-Nobau, Núria Oliveras-Cañellas, Wifredo Ricart, Priya P. Karmali, Kiyoshi Tachikawa, Pad Chivukula, Francesc Villarroya, Miguel López, Marta Giralt, José Manuel Fernández-Real, José María Moreno-Navarrete
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 599-613 (2022)
Circulating lipopolysaccharide-binding protein (LBP) is increased in individuals with liver steatosis. We aimed to evaluate the possible impact of liver LBP downregulation using lipid nanoparticle-containing chemically modified LBP small interfering
Externí odkaz:
https://doaj.org/article/2318b693c0cb490ab904a421bf554622
Autor:
Jessica Latorre, Francisco Ortega, Núria Oliveras-Cañellas, Ferran Comas, Aina Lluch, Aleix Gavaldà-Navarro, Samantha Morón-Ros, Wifredo Ricart, Francesc Villarroya, Marta Giralt, José Manuel Fernández-Real, José María Moreno-Navarrete
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 870-879 (2022)
Lipopolysaccharide binding protein (Lbp) has been recently identified as a relevant component of innate immunity response associated to adiposity. Here, we aimed to investigate the impact of adipose tissue Lbp on weight gain and white adipose tissue
Externí odkaz:
https://doaj.org/article/f9dbfee1ff5c4a26b586d69304553e65
Autor:
Jèssica Latorre, Cristina Martínez, Francisco Ortega, Núria Oliveras-Cañellas, Francisco Díaz-Sáez, Julian Aragonés, Marta Camps, Anna Gumà, Wifredo Ricart, José Manuel Fernández-Real, José María Moreno-Navarrete
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 156, Iss , Pp 113972- (2022)
Objective: To investigate the potential role of EGFR, ErbBs receptors and neuregulins in human adipose tissue physiology in obesity. Methods: Gene expression analysis in human subcutaneous (SAT) and visceral (VAT) adipose tissue in three independent
Externí odkaz:
https://doaj.org/article/d01dae50602f4a4689f0e10ec081498a
Autor:
Jèssica Latorre, Jordi Mayneris-Perxachs, Núria Oliveras-Cañellas, Francisco Ortega, Ferran Comas, José Manuel Fernández-Real, José María Moreno-Navarrete
Publikováno v:
EBioMedicine, Vol 85, Iss , Pp 104302- (2022)
Summary: Background: Adipose tissue is a source of multiple factors that modulate systemic insulin sensitivity and cardiovascular risk. Taurine is obtained from the diet but it is less known that it is endogenously synthesized by cysteine dioxygenase
Externí odkaz:
https://doaj.org/article/17ec57620e7345589730d957d013cb6e
Autor:
Cristina Martínez, Jèssica Latorre, Francisco Ortega, María Arnoriaga-Rodríguez, Aina Lluch, Núria Oliveras-Cañellas, Francisco Díaz-Sáez, Julian Aragonés, Marta Camps, Anna Gumà, Wifredo Ricart, José Manuel Fernández-Real, José María Moreno-Navarrete
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Neuregulin 4 (NRG4) has been described to improve metabolic disturbances linked to obesity status in rodent models. The findings in humans are controversial. We aimed to investigate circulating NRG4 in association with insulin action in humans and th
Externí odkaz:
https://doaj.org/article/12e2abad95514b38acec114a873da90c