Diaphragm impairment in patients admitted for severe COVID-19

Autor: Laura López-Viñas, Juan Vega-Villar, Esmeralda Rocío-Martín, Patricia García-García, Elena De La Rosa Santiago, Jose María Galván-Román, Rybel Wix-Ramos

Publikováno v: European Journal of Translational Myology (2022)

Among patients affected by the virus COVID-19, physicians have observed ventilation disorders. It is relevant to assess neurological involvement, including the role of diaphragmatic function. Its possible impairment could be related to the systemic i

Externí odkaz: https://doaj.org/article/bbff709d7f5e42839b2be9f62d1cd177

Occurrence of SARS-CoV-2 viremia is associated with genetic variants of genes related to COVID-19 pathogenesis

Autor: Emilia Roy-Vallejo, Sara Fernández De Córdoba-Oñate, Pablo Delgado-Wicke, Ana Triguero-Martínez, Nuria Montes, Rosa Carracedo-Rodríguez, Nelly Zurita-Cruz, Ana Marcos-Jiménez, Amalia Lamana, José María Galván-Román, Gonzalo Villapalos García, Pablo Zubiaur, Marianela Ciudad, Laura Rabes, Marta Sanz, Carlos Rodríguez, Almudena Villa, Jesús Álvarez Rodríguez, Celeste Marcos, Julia Hernando, Paula Díaz-Fernández, Francisco Abad, Ignacio de los Santos, Diego A. Rodríguez Serrano, Rosario García-Vicuña, Carmen Suárez Fernández, Rosa P. Gomariz, Cecilia Muñoz-Calleja, Elena Fernández-Ruiz, Isidoro González-Álvaro, Laura Cardeñoso, the PREDINMUN-COVID Group

Publikováno v: Frontiers in Medicine, Vol 10 (2023)

IntroductionSARS-CoV-2 viral load has been related to COVID-19 severity. The main aim of this study was to evaluate the relationship between SARS-CoV-2 viremia and SNPs in genes previously studied by our group as predictors of COVID-19 severity.Mater

Externí odkaz: https://doaj.org/article/8ca2939964894199a76694e0185eb3b7

SARS-CoV-2 Viremia Precedes an IL6 Response in Severe COVID-19 Patients: Results of a Longitudinal Prospective Cohort

Autor: Emilia Roy-Vallejo, Laura Cardeñoso, Ana Triguero-Martínez, Marta Chicot Llano, Nelly Zurita, Elena Ávalos, Ana Barrios, Julia Hernando, Javier Ortiz, Sebastián C. Rodríguez-García, Marianela Ciudad Sañudo, Celeste Marcos, Elena García Castillo, Leticia Fontán García-Rodrigo, Begoña González, Rosa Méndez, Isabel Iturrate, Ancor Sanz-García, Almudena Villa, Ana Sánchez-Azofra, Begoña Quicios, David Arribas, Jesús Álvarez Rodríguez, Pablo Patiño, Marina Trigueros, Miren Uriarte, Alexandra Martín-Ramírez, Cristina Arévalo Román, José María Galván-Román, Rosario García-Vicuña, Julio Ancochea, Cecilia Muñoz-Calleja, Elena Fernández-Ruiz, Rafael de la Cámara, Carmen Suárez Fernández, Isidoro González-Álvaro, Diego A. Rodríguez-Serrano, the PREDINMUN-COVID Group, Jesús Sanz, Pedro Casado, Ángela Gutiérrez, Azucena Bautista, Pilar Hernández, Nuria Ruiz Giménez, Berta Moyano, Paloma Gil, María Jesús Delgado, Pedro Parra, Beatriz Sánchez, Carmen Sáez, Marta Fernández Rico, Diego Domingo García, Teresa Alarcón Cavero, María Auxiliadora Semiglia Chong, Ainhoa Gutiérrez Cobos, Santos Castañeda, Irene Llorente, Eva G. Tomero, Noelia García Castañeda, Nuria Montes, Cristina Dominguez Peña, David Jiménez Jiménez, Pablo Villamayor, Alfonso Canabal, Tamara Alonso, Carolina Cisneros, Claudia Valenzuela, Francisco Javier García Pérez, Rosa María Girón, Javier Aspa, M. del Perpetuo Socorro Churruca, Enrique Zamora, Adrián Martínez, Mar Barrio Mayo, Rosalina Henares Espi, Francisco Sánchez-Madrid, Enrique Martín Gayo, Ildefonso Sánchez-Cerrillo, Ana Marcos Jimenez, Pedro Martínez-Fleta, Celia López-Sanz, Ligia Gabrie, Luciana del Campo Guerola, Reyes Tejedor, Rosa Carracedo Rodríguez

Publikováno v: Frontiers in Medicine, Vol 9 (2022)

BackgroundInterleukin 6 (IL6) levels and SARS-CoV-2 viremia have been correlated with COVID-19 severity. The association over time between them has not been assessed in a prospective cohort. Our aim was to evaluate the relationship between SARS-CoV-2

Externí odkaz: https://doaj.org/article/2e8c5c8c3fe4433d9e6a941239aec30c

Usefulness of circulating microRNAs miR-146a and miR-16-5p as prognostic biomarkers in community-acquired pneumonia.

Autor: José María Galván-Román, Ángel Lancho-Sánchez, Sergio Luquero-Bueno, Lorena Vega-Piris, Jose Curbelo, Marcos Manzaneque-Pradales, Manuel Gómez, Hortensia de la Fuente, Mara Ortega-Gómez, Javier Aspa

Publikováno v: PLoS ONE, Vol 15, Iss 10, p e0240926 (2020)

IntroductionPatients with community-acquired pneumonia (CAP) undergo a dysregulated host response that is related to mortality. MicroRNAs (miRNAs) participate in this response, but their expression pattern and their role as biomarkers in CAP have not

Externí odkaz: https://doaj.org/article/2ec9376c856a41ca932babac429ba4da

Inflammation biomarkers in blood as mortality predictors in community-acquired pneumonia admitted patients: Importance of comparison with neutrophil count percentage or neutrophil-lymphocyte ratio.

Autor: Jose Curbelo, Sergio Luquero Bueno, José María Galván-Román, Mara Ortega-Gómez, Olga Rajas, Guillermo Fernández-Jiménez, Lorena Vega-Piris, Francisco Rodríguez-Salvanes, Belén Arnalich, Ana Díaz, Ramón Costa, Hortensia de la Fuente, Ángel Lancho, Carmen Suárez, Julio Ancochea, Javier Aspa

Publikováno v: PLoS ONE, Vol 12, Iss 3, p e0173947 (2017)

INTRODUCTION:The increase and persistence of inflammation in community-acquired pneumonia (CAP) patients can lead to higher mortality. Biomarkers capable of measuring this inadequate inflammatory response are likely candidates to be related with a ba

Externí odkaz: https://doaj.org/article/16a1e19223b3469292b62934a7a6d0eb