Polymorphisms within the TNFSF4 and MAPKAPK2 Loci Influence the Risk of Developing Invasive Aspergillosis: A Two-Stage Case Control Study in the Context of the aspBIOmics Consortium

Autor: Jose Manuel Sánchez-Maldonado, Ana Moñiz-Díez, Rob ter Horst, Daniele Campa, Antonio José Cabrera-Serrano, Manuel Martínez-Bueno, María del Pilar Garrido-Collado, Francisca Hernández-Mohedo, Laura Fernández-Puerta, Miguel Ángel López-Nevot, Cristina Cunha, Pedro Antonio González-Sierra, Jan Springer, Michaela Lackner, Laura Alcazar-Fuoli, Luana Fianchi, José María Aguado, Livio Pagano, Elisa López-Fernández, Esther Clavero, Leonardo Potenza, Mario Luppi, Lucia Moratalla, Carlos Solano, Antonio Sampedro, Manuel Cuenca-Estrella, Cornelia Lass-Flörl, PCRAGA Study Group, Federico Canzian, Juergen Loeffler, Yang Li, Hermann Einsele, Mihai G. Netea, Lourdes Vázquez, Agostinho Carvalho, Manuel Jurado, Juan Sainz

Publikováno v: Journal of Fungi, Vol 7, Iss 1, p 4 (2020)

Here, we assessed whether 36 single nucleotide polymorphisms (SNPs) within the TNFSF4 and MAPKAPK2 loci influence the risk of developing invasive aspergillosis (IA). We conducted a two-stage case control study including 911 high-risk patients diagnos

Externí odkaz: https://doaj.org/article/7ffd7f2e74154c68aeb332e792fad767

Functional genetic variants in atg10 are associated with acute myeloid leukemia

Autor: Paula Ludovico, Agostinho Carvalho, Cristina Cunha, Belém Sampaio-Marques, A. C. Areias, Juan Sainz, Ângela Fernandes, Hugo Sousa, Jose Manuel Sánchez-Maldonado, Isabel Castro

Publikováno v: Cancers
Volume 13
Issue 6
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Cancers, Vol 13, Iss 1344, p 1344 (2021)
Digibug. Repositorio Institucional de la Universidad de Granada
instname

This research was funded by FEDER and Foundation for Science and Technology (FCT), grant number POCI-01-0145-FEDER-028159 and POCI-01-0145-FEDER-030782); by Fondo de Investigaciones Sanitarias (Madrid, Spain), grant number ISCIII-FEDER PI20/01845, IS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82bf967db880be4b166d1cf2e2a03e3a
https://hdl.handle.net/10216/150482

NFKB2 polymorphisms associate with the risk of developing rheumatoid arthritis and response to TNF inhibitors: Results from the REPAIR consortium

Autor: Helena Canhão, Pablo Conesa-Zamora, Salvatore De Vita, Alfons A den Broeder, Sonia Muñoz-Peña, Antonio García, Luca Quartuccio, Rafael Cáliz, Yang Li, Alejandro Escudero, Mihai G. Netea, Svend Erik Hove Jacobsen, Eduardo Collantes, Ana Rodríguez-Ramos, Manuel Jurado, Merete Lund Hetland, Miguel Ferrer, Manuel Martínez-Bueno, João Eurico Fonseca, Jose Manuel Sánchez-Maldonado, Rob ter Horst, Miguel A. López-Nevot, Signe Bek Sørensen, Marieke J H Coenen, Juan Sainz, I. Filipescu, Eva Perez-Pampin, Vibeke Andersen, Ana Moñiz-Díez, Bente Glintborg

Publikováno v: Scientific Reports, 10
Digibug. Repositorio Institucional de la Universidad de Granada
Consejo Superior de Investigaciones Científicas (CSIC)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Manuel Sánchez-Maldonado, J, Martínez-Bueno, M, Canhão, H, ter Horst, R, Muñoz-Peña, S, Moñiz-Díez, A, Rodríguez-Ramos, A, Escudero, A, Sorensen, S B, Hetland, M L, Ferrer, M A, Glintborg, B, Filipescu, I, Pérez-Pampin, E, Conesa-Zamora, P, García, A, den Broeder, A, De Vita, S, Hove Jacobsen, S E, Collantes, E, Quartuccio, L, Netea, M G, Li, Y, Fonseca, J E, Jurado, M, López-Nevot, M Á, Coenen, M J H, Andersen, V, Cáliz, R & Sainz, J 2020, ' NFKB2 polymorphisms associate with the risk of developing rheumatoid arthritis and response to TNF inhibitors : Results from the REPAIR consortium ', Scientific Reports, vol. 10, 4316 . https://doi.org/10.1038/s41598-020-61331-5
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Scientific Reports
Scientific Reports, 10(1):4316. Nature Publishing Group
Manuel Sánchez-Maldonado, J, Martínez-Bueno, M, Canhão, H, ter Horst, R, Muñoz-Peña, S, Moñiz-Díez, A, Rodríguez-Ramos, A, Escudero, A, Sorensen, S B, Hetland, M L, Ferrer, M A, Glintborg, B, Filipescu, I, Pérez-Pampin, E, Conesa-Zamora, P, García, A, den Broeder, A, De Vita, S, Hove Jacobsen, S E, Collantes, E, Quartuccio, L, Netea, M G, Li, Y, Fonseca, J E, Jurado, M, López-Nevot, M Á, Coenen, M J H, Andersen, V, Cáliz, R & Sainz, J 2020, ' NFKB2 polymorphisms associate with the risk of developing rheumatoid arthritis and response to TNF inhibitors : Results from the REPAIR consortium ', Scientific Reports, vol. 10, no. 1, 4316 . https://doi.org/10.1038/s41598-020-61331-5

We thank all participants who have agreed to participate in this study. Authors also thank Maria Dolores Casares, Angeles Molina, Carmen Oloriz for the collection of Spanish samples and Hans Jurgen Hoffmann, Marianne Thomsen, Vibeke Ostergaard Thomse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f17f95bce91f62736192280b55f57ac
http://hdl.handle.net/2066/218299

Steroid hormone-related polymorphisms associate with the development of bone erosions in rheumatoid arthritis and help to predict disease progression: Results from the REPAIR consortium

Autor: Alfonso González-Utrilla, Alfons A den Broeder, Rafael Cáliz, Juan Sainz, Jose Manuel Sánchez-Maldonado, Romana T. Netea-Maier, Eduardo Collantes-Estevez, Rob ter Horst, María José Soto-Pino, Ana Rodríguez-Ramos, Miguel Ferrer, Yang Li, Marieke J H Coenen, Manuel Martínez-Bueno, Eva Perez-Pampin, Olivier B. Bakker, L. M. Canet, Manuel Jurado, Alejandro Escudero, Mihai G. Netea, João Eurico Fonseca, Juana Segura-Catena, Carmen Belén Lupiañez, Miguel Ángel López Nevot, Helena Canhão, Antonio García

Publikováno v: Scientific Reports, 9:14812. Nature Publishing Group
Scientific Reports, 9
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Scientific Reports

Here, we assessed whether 41 SNPs within steroid hormone genes associated with erosive disease. The most relevant finding was the rheumatoid factor (RF)-specific effect of the CYP1B1, CYP2C9, ESR2, FcγR3A, and SHBG SNPs to modulate the risk of bone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21dd29b3261de56f061be748b3abedb
https://research.rug.nl/en/publications/e560facc-1904-49a4-8d43-85e5c6e256fe

Polymorphisms at phase I-metabolizing enzyme and hormone receptor loci influence the response to anti-TNF therapy in rheumatoid arthritis patients

Autor: João Eurico Fonseca, Vibeke Andersen, Miguel Ángel López Nevot, Manuel Martínez-Bueno, Federico Canzian, Salvatore De Vita, Rafael Cáliz, Alfons A den Broeder, Antonio García, Sven-Erik Jacobsen, Juana Segura-Catena, Jose Manuel Sánchez-Maldonado, Ana Rodríguez-Ramos, Signe B. Sorensen, Miguel Ferrer, Eduardo Collantes-Estevez, Merete Lund Hetland, Alfonso González-Utrilla, Juan Sainz, Helena Canhão, Pablo Conesa-Zamora, L. M. Canet, I. Filipescu, Carmen Belén Lupiañez, Marieke J H Coenen, María José Soto-Pino, B. Glintborg, Alejandro Escudero, Luca Quartuccio, Eva Perez-Pampin

Publikováno v: Canet, L M, Sánchez-Maldonado, J M, Cáliz, R, Ramos, A R, Lupiañez, C B, Canhão, H, Martínez-Bueno, M, Escudero, A, Segura-Catena, J, Sorensen, S B, Hetland, M L, Soto-Pino, M J, Ferrer, M A, García, A, Glintborg, B, Filipescu, I, Pérez-Pampin, E, González-Utrilla, A, Nevot, M Á L, Conesa-Zamora, P, Broeder, A D, De Vita, S, Jacobsen, S E H, Collantes-Estevez, E, Quartuccio, L, Canzian, F, Fonseca, J E, Coenen, M J H, Andersen, V & Sainz, J 2019, ' Polymorphisms at phase I-metabolizing enzyme and hormone receptor loci influence the response to anti-TNF therapy in rheumatoid arthritis patients ', The Pharmacogenomics Journal, vol. 19, pp. 83-96 . https://doi.org/10.1038/s41397-018-0057-x
Pharmacogenomics Journal, 19, 1, pp. 83-96
Canet, L M, Sánchez-Maldonado, J M, Cáliz, R, Rodríguez-Ramos, A, Lupiañez, C B, Canhão, H, Martínez-Bueno, M, Escudero, A, Segura-Catena, J, Sorensen, S B, Hetland, M L, Soto-Pino, M J, Ferrer, M A, García, A, Glintborg, B, Filipescu, I, Pérez-Pampin, E, González-Utrilla, A, Nevot, M Á L, Conesa-Zamora, P, Broeder, A D, De Vita, S, Jacobsen, S E H, Collantes-Estevez, E, Quartuccio, L, Canzian, F, Fonseca, J E, Coenen, M J H, Andersen, V & Sainz, J 2019, ' Polymorphisms at phase I-metabolizing enzyme and hormone receptor loci influence the response to anti-TNF therapy in rheumatoid arthritis patients ', The Pharmacogenomics Journal, vol. 19, no. 1, pp. 83-96 . https://doi.org/10.1038/s41397-018-0057-x
Pharmacogenomics Journal, 19, 83-96

© Springer Nature Limited 2018
The aim of this case-control study was to evaluate whether 47 single-nucleotide polymorphisms (SNPs) in steroid hormone-related genes are associated with the risk of RA and anti-TNF drug response. We conducted a c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a8fdd6bbd1eeec59074f70afbd182e
https://hdl.handle.net/10451/52345