Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jose M. Tirado-Vélez"'
Autor:
Adela G. de la Campa, María J. Ferrándiz, Antonio J. Martín-Galiano, María T. García, Jose M. Tirado-Vélez
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
The bacterial chromosome is compacted in a manner optimal for DNA transactions to occur. The degree of compaction results from the level of DNA-supercoiling and the presence of nucleoid-binding proteins. DNA-supercoiling is homeostatically maintained
Externí odkaz:
https://doaj.org/article/fd0d365ef859436a9b085adb1cf2d645
Autor:
Antonio A. de Vasconcelos Junior, Jose M. Tirado-Vélez, Antonio J. Martín-Galiano, Diego Megias, María-José Ferrándiz, Pablo Hernández, Mónica Amblar, Adela G. de la Campa
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 6; Pages: 5973
The DNA topoisomerases gyrase and topoisomerase I as well as the nucleoid-associated protein HU maintain supercoiling levels in Streptococcus pneumoniae, a main human pathogen. Here, we characterized, for the first time, a topoisomerase I regulator p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0fad920ae936d7d7b200fde79b8f506
http://hdl.handle.net/10261/308017
http://hdl.handle.net/10261/308017
Autor:
María T. García, David Carreño, José M. Tirado-Vélez, María J. Ferrándiz, Liliana Rodrigues, Begoña Gracia, Mónica Amblar, José A. Ainsa, Adela G. de la Campa
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
The spread of multidrug-resistant isolates of Mycobacterium tuberculosis requires the discovery of new drugs directed to new targets. In this study, we investigated the activity of two boldine-derived alkaloids, seconeolitsine (SCN) and N-methyl-seco
Externí odkaz:
https://doaj.org/article/5476a01f6c15470fa276df089ffbc49d