Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jose M. Ramos-Pittol"'
Autor:
Tatiana Lopes, David CD. Hope, Jose M. Ramos-Pittol, Anna Curtis, Jed V. Shrewsbury, Iona Davies, Zijing Zhou, Alessandro Sardini, James S. Minnion, Dirk Dormann, Gavin A. Bewick, Kevin G. Murphy, David Carling, Stephen R. Bloom, Tricia MM. Tan, Bryn M. Owen
Publikováno v:
Molecular Metabolism, Vol 89, Iss , Pp 102024- (2024)
Objective: Glucagon has long been proposed as a component of multi-agonist obesity therapeutics due to its ability to induce energy expenditure and cause weight loss. However, chronic glucagon-receptor agonism has been associated with a reduction in
Externí odkaz:
https://doaj.org/article/d0ac3e309a1b4c52b8fc5d7efd834e06
Autor:
Jose M. Ramos-Pittol, Isabel Fernandes-Freitas, Alexandra Milona, Stephen M. Manchishi, Kara Rainbow, Brian Y. H. Lam, John A. Tadross, Anthony Beucher, William H. Colledge, Inês Cebola, Kevin G. Murphy, Irene Miguel-Aliaga, Giles S. H. Yeo, Waljit S. Dhillo, Bryn M. Owen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Coupling the release of pituitary hormones to the developmental stage of the oocyte is essential for female fertility. It requires estrogen to restrain kisspeptin (KISS1)-neuron pulsatility in the arcuate hypothalamic nucleus, while also exe
Externí odkaz:
https://doaj.org/article/59195b68a82445d591a6b19294b35586
Autor:
Alexandra Milona, Vittoria Massafra, Harmjan Vos, Jyoti Naik, Natalia Artigas, Helen A.B. Paterson, Ingrid T.G.W. Bijsmans, Ellen C.L. Willemsen, Jose M. Ramos Pittol, Irene Miguel-Aliaga, Piter Bosma, Boudewijn M.T. Burgering, Catherine Williamson, Santiago Vernia, Waljit S. Dhillo, Saskia W.C. van Mil, Bryn M. Owen
Publikováno v:
Molecular Metabolism, Vol 30, Iss , Pp 221-229 (2019)
Objective: Coupling metabolic and reproductive pathways is essential for the survival of species. However, the functions of steroidogenic enzymes expressed in metabolic tissues are largely unknown. Methods and results: Here, we show that in the liver
Externí odkaz:
https://doaj.org/article/f03fe7de90804886b4db2443d1f7e1c8
Autor:
Koos de Wit, Ulrich Beuers, Anna Mukha, Edwin C. A. Stigter, M. Can Gulersonmez, Jose M. Ramos Pittol, Sabine Middendorp, R. Bart Takkenberg, Saskia W. C. van Mil
Publikováno v:
Liver International. 43
Autor:
Koos de Wit, Ulrich Beuers, Anna Mukha, Edwin C. A. Stigter, M. Can Gulersonmez, Jose M. Ramos Pittol, Sabine Middendorp, R. Bart Takkenberg, Saskia W. C. van Mil
Publikováno v:
Liver international. Wiley-Blackwell
BACKGROUND AND AIMS: Recurrent hepatic encephalopathy (HE) is characterized by hyperammonemia in combination with neuropsychiatric abnormalities and is treated with lactulose and rifaximin. Rifaximin is a Pregnane X Receptor (PXR) agonist with low sy