Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jose M. Lemme-Dumit"'
Autor:
Girmay Desalegn, Chitradevi S. Tamilselvi, Jose M. Lemme-Dumit, Shannon J. Heine, Dylan Dunn, Esther Ndungo, Neeraj Kapoor, Edwin V. Oaks, Jeff Fairman, Marcela F. Pasetti
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-11 (2024)
Abstract Diarrhea caused by Shigella has been associated with high morbidity and mortality in young children worldwide. There are no licensed vaccines, and those clinically advanced have restricted coverage as they elicit serotype-specific immunity w
Externí odkaz:
https://doaj.org/article/1190d955ae2e4a24a0cee0e6a316598b
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Polymorphonuclear neutrophils (PMN) are recruited to the gastrointestinal mucosa in response to inflammation, injury, and infection. Here, we report the development and the characterization of an ex vivo tissue coculture model consisting of
Externí odkaz:
https://doaj.org/article/4f18f0a1df4c417bbe8826992fa72061
Autor:
Bing Ma, Sripriya Sundararajan, Gita Nadimpalli, Michael France, Elias McComb, Lindsay Rutt, Jose M. Lemme-Dumit, Elise Janofsky, Lisa S. Roskes, Pawel Gajer, Li Fu, Hongqiu Yang, Mike Humphrys, Luke J. Tallon, Lisa Sadzewicz, Marcela F. Pasetti, Jacques Ravel, Rose M. Viscardi
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT “Leaky gut,” or high intestinal barrier permeability, is common in preterm newborns. The role of the microbiota in this process remains largely uncharacterized. We employed both short- and long-read sequencing of the 16S rRNA gene and me
Externí odkaz:
https://doaj.org/article/ac1c5db7656449f19104f3a64c3a8c0d
Autor:
Jose M. Lemme-Dumit, Yang Song, Hnin Wai Lwin, Claudia Hernandez-Chavez, Sripriya Sundararajan, Rose M. Viscardi, Jacques Ravel, Marcela F. Pasetti, Bing Ma
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Intestinal barrier immaturity, or “leaky gut”, is the proximate cause of susceptibility to necrotizing enterocolitis in preterm neonates. Exacerbated intestinal immune responses, gut microbiota dysbiosis, and heightened barrier injury are conside
Externí odkaz:
https://doaj.org/article/b8c2b56212014b0ab47a49d61ff45358
Autor:
Esther Ndungo, Liana R. Andronescu, Andrea G. Buchwald, Jose M. Lemme-Dumit, Patricia Mawindo, Neeraj Kapoor, Jeff Fairman, Miriam K. Laufer, Marcela F. Pasetti
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Shigella is the second leading cause of diarrheal diseases, accounting for >200,000 infections and >50,000 deaths in children under 5 years of age annually worldwide. The incidence of Shigella-induced diarrhea is relatively low during the first year
Externí odkaz:
https://doaj.org/article/b2227dc56a74481c84a7e69daf29f1c8
Autor:
Gaelle Noel, Julie G. In, Jose M. Lemme-Dumit, Lauren R. DeVine, Robert N. Cole, Anthony L. Guerrerio, James D. Campbell, Olga Kovbasnjuk, Marcela F. Pasetti
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Breastfeeding has been associated with long lasting health benefits. Nutrients and bioactive components of human breast milk promote cell growth, immune development, and shield the infant gut from insults and microbial threats. The molecular and cell
Externí odkaz:
https://doaj.org/article/8db1528c7b484bdfa5eb022dd3ec1bb2
Autor:
Jose M. Lemme-Dumit
Publikováno v:
mSphere, Vol 5, Iss 4 (2020)
ABSTRACT Jose Lemme-Dumit works in the field of mucosal immunology and vaccines. In this mSphere of Influence article, he reflects on how two papers, “Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barret
Externí odkaz:
https://doaj.org/article/277b4b2447c74cf6a9ea7394c16abae0
Publikováno v:
mBio. 13
Studies of mucosal immunity and microbial host cell interaction have traditionally relied on animal models andin vitrotissue culture using immortalized cancer cell lines, which yield nonphysiological and often unreliable results. Herein, we report th
Autor:
James D. Campbell, Marcela F. Pasetti, Gaelle Noel, Olga Kovbasnjuk, Robert N. Cole, Jose M. Lemme-Dumit, Anthony L. Guerrerio, Lauren R. DeVine, Julie G. In
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Breastfeeding has been associated with long lasting health benefits. Nutrients and bioactive components of human breast milk promote cell growth, immune development, and shield the infant gut from insults and microbial threats. The molecular and cell
Autor:
Neeraj Kapoor, Liana R. Andronescu, Esther Ndungo, Jose M. Lemme-Dumit, Patricia Mawindo, Marcela F. Pasetti, Jeff Fairman, Andrea G. Buchwald, Miriam K. Laufer
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Shigellais the second leading cause of diarrheal diseases, accounting for >200,000 infections and >50,000 deaths in children under 5 years of age annually worldwide. The incidence ofShigella-induced diarrhea is relatively low during the first year of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1bbc7dd3f41a974af4f55546ca6dab9
https://doi.org/10.1101/2021.05.21.445178
https://doi.org/10.1101/2021.05.21.445178