Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jose M. Honrubia"'
Autor:
Jose M. Honrubia, Jose R. Valverde, Diego Muñoz-Santos, Jorge Ripoll-Gómez, Nuria de la Blanca, Jorge Izquierdo, Marta Villarejo-Torres, Ana Marchena-Pasero, María Rueda-Huélamo, Ivan Nombela, Mercedes Ruiz-Yuste, Sonia Zuñiga, Isabel Sola, Luis Enjuanes
Publikováno v:
Viruses, Vol 16, Iss 8, p 1214 (2024)
The interaction between SARS-CoV PDZ-binding motifs (PBMs) and cellular PDZs is responsible for virus virulence. The PBM sequence present in the 3a and envelope (E) proteins of SARS-CoV can potentially bind to over 400 cellular proteins containing PD
Externí odkaz:
https://doaj.org/article/46ba8b5748c848e3b5f47b5fef069122
Autor:
Carlos Castaño-Rodríguez, Jose M. Honrubia, Javier Gutierrez-Álvarez, Marta L. DeDiego, Jose L. Nieto-Torres, Jose M. Jimenez-Guardeño, Jose A. Regla-Nava, Raul Fernandez-Delgado, Carmina Verdia-Báguena, Maria Queralt-Martín, Grazyna Kochan, Stanley Perlman, Vicente M. Aguilella, Isabel Sola, Luis Enjuanes
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
Externí odkaz:
https://doaj.org/article/3b59c2f9e8454afdae7dcb85b87f2ee3
Autor:
Jose M. Honrubia, Javier Gutierrez-Álvarez, Alejandro Sanz-Bravo, Ezequiel González-Miranda, Diego Muñoz-Santos, Carlos Castaño-Rodriguez, Li Wang, Marta Villarejo-Torres, Jorge Ripoll-Gómez, Ana Esteban, Raul Fernandez-Delgado, Pedro José Sánchez-Cordón, Juan Carlos Oliveros, Stanley Perlman, Paul B. McCray, Isabel Sola, Luis Enjuanes
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Coronaviruses (CoVs) of genera α, β, γ, and δ encode proteins that have a PDZ-binding motif (PBM) consisting of the last four residues of the envelope (E) protein (PBM core). PBMs may bind over 400 cellular proteins containing PDZ domain
Externí odkaz:
https://doaj.org/article/748cab695f5f46f68ab0f4651f18e0e3
Autor:
Carlos Castaño-Rodriguez, Jose M. Honrubia, Javier Gutiérrez-Álvarez, Marta L. DeDiego, Jose L. Nieto-Torres, Jose M. Jimenez-Guardeño, Jose A. Regla-Nava, Raul Fernandez-Delgado, Carmina Verdia-Báguena, Maria Queralt-Martín, Grazyna Kochan, Stanley Perlman, Vicente M. Aguilella, Isabel Sola, Luis Enjuanes
Publikováno v:
mBio, Vol 9, Iss 3 (2018)
ABSTRACT Viroporins are viral proteins with ion channel (IC) activity that play an important role in several processes, including virus replication and pathogenesis. While many coronaviruses (CoVs) encode two viroporins, severe acute respiratory synd
Externí odkaz:
https://doaj.org/article/31ebed5e7b7044608ea80455fa5b9c27
Autor:
Carlos, Castaño-Rodriguez, Jose M, Honrubia, Javier, Gutiérrez-Álvarez, Isabel, Sola, Luis, Enjuanes
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2256
Viruses have evolved to interact with their hosts. Some viruses such as human papilloma virus, dengue virus, SARS-CoV, or influenza virus encode proteins including a PBM that interact with cellular proteins containing PDZ domains. There are more than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::72fadc172738a10fff77ffc2453b9a76
https://pubmed.ncbi.nlm.nih.gov/34014525
https://pubmed.ncbi.nlm.nih.gov/34014525
Autor:
Luis Enjuanes, Isabel Sola, Sonia Zúñiga, José M. Honrubia, Melissa Bello-Pérez, Alejandro Sanz-Bravo, Ezequiel González-Miranda, Jesús Hurtado-Tamayo, Ricardo Requena-Platek, Li Wang, Diego Muñoz-Santos, Carlos M. Sánchez, Ana Esteban, Jorge Ripoll-Gómez
Publikováno v:
Current Research in Immunology, Vol 3, Iss , Pp 151-158 (2022)
Coronaviruses (CoVs) have the largest genome among RNA viruses and store large amounts of information without genome integration as they replicate in the cell cytoplasm. The replication of the virus is a continuous process, whereas the transcription
Externí odkaz:
https://doaj.org/article/e04daf16ecae41259caffc07dcb5dc21
Autor:
Javier Gutiérrez-Álvarez, José M. Honrubia, Raúl Fernández-Delgado, Li Wang, Carlos Castaño-Rodríguez, Sonia Zúñiga, Isabel Sola, Luis Enjuanes
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
The emergence of the new highly pathogenic human coronavirus SARS-CoV-2 that has already infected more than 80 million persons, killing nearly two million of them, clearly indicates the need to design efficient and safe vaccines protecting from these
Externí odkaz:
https://doaj.org/article/c01fb9a68b5a453eacd5373a7db07a1d