Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jose M. Gonzalez-Ros"'
Autor:
María Lourdes Renart, Ana Marcela Giudici, Carlos Coll-Díez, José M. González-Ros, José A. Poveda
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1376 (2023)
Here, we report an allosteric effect of an anionic phospholipid on a model K+ channel, KcsA. The anionic lipid in mixed detergent–lipid micelles specifically induces a change in the conformational equilibrium of the channel selectivity filter (SF)
Externí odkaz:
https://doaj.org/article/fc50efd2f6074f44bed5c66947a718b2
Autor:
Maria D, Castro-Galache, Jose A, Ferragut, Victor M, Barbera, Elena, Martín-Orozco, Jose M, Gonzalez-Ros, Pilar, Garcia-Morales, Miguel, Saceda
Publikováno v:
International journal of cancer. 104(5)
The main goal of our study has been to analyze the efficiency of new anticancer drugs, specifically histone deacetylase inhibitors, in tumor cells bearing a multidrug resistance phenotype. We report that the histone deacetylase inhibitors, Trichostat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e7006162e851d114a24ed8b74930503
https://pubmed.ncbi.nlm.nih.gov/12594812
https://pubmed.ncbi.nlm.nih.gov/12594812
Autor:
Raúl Cobo, Magdalena Nikolaeva, Armando Alberola-Die, Gregorio Fernández-Ballester, José M. González-Ros, Isabel Ivorra, Andrés Morales
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Nicotinic acetylcholine (ACh) receptors (nAChRs) are included among the targets of a variety of local anesthetics, although the molecular mechanisms of blockade are still poorly understood. Some local anesthetics, such as lidocaine, act on nAChRs by
Externí odkaz:
https://doaj.org/article/ccd197914b5f450a86892ee1ba3afd4b
Autor:
Jose A. Ferragut, Debbie L. Weir, Darrell L. Peterson, Jose M. Gonzalez-Ros, Richard C. Franson, Marino Martinez-Carrion
Publikováno v:
Archives of Biochemistry and Biophysics. 235:628-635
The purification of highly homogeneous, phospholipase-free alpha-bungarotoxin (alpha-Bgt) from the venom of the elapid Bungarus multicinctus or from commercial samples of alpha-Bgt is described. The method combines a conventional procedure for the pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c50cf7fa4034f121189e114c07245586
https://doi.org/10.1016/0003-9861(84)90237-6
https://doi.org/10.1016/0003-9861(84)90237-6
Publikováno v:
Biochemical Pharmacology. 37:2133-2138
Absorbance and fluorescence quenching monitoring of the binding of the anthracyclines adriamycin (ADM) and daunomycin (DNM) to calf thymus DNA, provides reproducible binding data only when moderate drug/DNA molar ratios are used in the assays. Under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e572357b17e9ba70a109e522b39f7476
https://doi.org/10.1016/0006-2952(88)90571-0
https://doi.org/10.1016/0006-2952(88)90571-0
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 733:223-233
A rapid, simple and reproducible method has been developed for the measurement of ion tracer flux with both native membrane vesicles and reconstituted lipid vesicle systems. Following the absorption of vesicles onto glass fiber filters, tracer flux i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8918aa15cbb4e2ed35b448a0931f781b
https://doi.org/10.1016/0005-2736(83)90526-6
https://doi.org/10.1016/0005-2736(83)90526-6
Publikováno v:
Proceedings of the National Academy of Sciences. 77:1796-1800
Purified acetylcholine receptor and total lipids, both extracted from Torpedo californica electroplax, were utilized to reconstitute chemically excitable membrane vesicles. Reconstitution was achieved by dialysis of the extraction detergent, octyl be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08dfab7e678e083b92716fde30ea98e0
https://doi.org/10.1073/pnas.77.4.1796
https://doi.org/10.1073/pnas.77.4.1796
Autor:
David P. Richman, Mirta Mihovilovic, Diana Donnelly, José A. Ferragut, Jose M. Gonzalez-Ros, Marino Martinez-Carrion
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 81(24)
We have employed several monoclonal antibodies (mAbs) directed against several regions of the acetylcholine receptor (AcChoR) to assist in the determination of the antigenic structure of this multisubunit glycoprotein and to better understand molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56eb80f546985cbe0f596cc04ed976d5
https://pubmed.ncbi.nlm.nih.gov/6096872
https://pubmed.ncbi.nlm.nih.gov/6096872
Autor:
Jose M. Gonzalez-Ros, A. Ribera
Publikováno v:
The International journal of biochemistry. 11(3-4)
1. 1. Phosphatidylcholine (PC) was the major phospholipid fraction in the embryonic encephalon, palmitic and oleic acids being the main acyl constituents. 2. 2. These fatty acids were poorly represented in phosphatidylethanolamine (PE), whereas stear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0035ef4f4c65f1c6ab52f72e58c45432
https://pubmed.ncbi.nlm.nih.gov/7389987
https://pubmed.ncbi.nlm.nih.gov/7389987
Publikováno v:
Archives of biochemistry and biophysics. 258(1)
Thermal perturbation techniques have been used to probe structural features of the nicotinic acetylcholine receptor (AcChR). The information obtained from differential scanning calorimetry (DSC) of AcChR membranes (M.C. Farach and M. Martinez-Carrion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::826e7c8ffc5136cbf7edb364b383e54d
https://pubmed.ncbi.nlm.nih.gov/3662540
https://pubmed.ncbi.nlm.nih.gov/3662540