Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jose M. González-Navajas"'
Autor:
Jongdae Lee, Beatriz Lozano-Ruiz, Fengyuan Mandy Yang, Dengxia Denise Fan, Liya Shen, Jose M. González-Navajas
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
During the last decade, immune checkpoint inhibition (ICI) has become a pillar of cancer therapy. Antibodies targeting CTLA-4 or PD-1/PD-L1 have been approved in several malignancies, with thousands of clinical trials currently underway. While the ma
Externí odkaz:
https://doaj.org/article/e990e46366cf4d8b8f73790fee639c6f
Autor:
Jose M. González-Navajas, Dengxia Denise Fan, Shuang Yang, Fengyuan Mandy Yang, Beatriz Lozano-Ruiz, Liya Shen, Jongdae Lee
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Although cancers arise from genetic mutations enabling cells to proliferate uncontrollably, they cannot thrive without failure of the anticancer immunity due in a large part to the tumor environment's influence on effector and regulatory T cells. The
Externí odkaz:
https://doaj.org/article/3d3d6fd74f6347d088b8c82513aa9a9b
Autor:
Jongdae Lee, Beatriz Lozano-Ruiz, Fengyuan Mandy Yang, Dengxia Denise Fan, Liya Shen, Jose M. González-Navajas
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
During the last decade, immune checkpoint inhibition (ICI) has become a pillar of cancer therapy. Antibodies targeting CTLA-4 or PD-1/PD-L1 have been approved in several malignancies, with thousands of clinical trials currently underway. While the ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb0e4896b9103b5da5c7d105d0e39b8
https://pubmed.ncbi.nlm.nih.gov/33777008
https://pubmed.ncbi.nlm.nih.gov/33777008
Autor:
Dongjie Wang, Wen Li, Natalie Albasha, Lindsey Griffin, Han Chang, Lauren Amaya, Sneha Ganguly, Liping Zeng, Bora Keum, José M. González-Navajas, Matt Levin, Zohreh AkhavanAghdam, Helen Snyder, David Schwartz, Ailin Tao, Laela M. Boosherhri, Hal M. Hoffman, Michael Rose, Monica Valeria Estrada, Nissi Varki, Scott Herdman, Maripat Corr, Nicholas J. G. Webster, Eyal Raz, Samuel Bertin
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-24 (2023)
Abstract Background Individuals with certain chronic inflammatory lung diseases have a higher risk of developing lung cancer (LC). However, the underlying mechanisms remain largely unknown. Here, we hypothesized that chronic exposure to house dust mi
Externí odkaz:
https://doaj.org/article/f506227a08414d8eb5c6d5a982b91b04
Autor:
Joon Haeng Rhee, In-Kyu Park, Jongdae Lee, Eyal Raz, Joanna C.K. Kim, Jose M. González–Navajas, Xiangli Li, Shee Eun Lee, Seol Hee Hong
Publikováno v:
Gastroenterology. 143:145-154
Background & Aims Foxp3 + T-regulatory cells (Tregs) maintain intestinal homeostasis under conditions of continuous challenge with inflammatory microbes. However, plasticity of the Treg population under certain conditions has been reported; Foxp3 + T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e974a1042a88fb6f50f1d757659b6229
https://doi.org/10.1053/j.gastro.2012.03.042
https://doi.org/10.1053/j.gastro.2012.03.042
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/481c4152c35e42f09a0271e9f18941e3
Autor:
Oriol Juanola, Paula Piñero, Isabel Gómez‐Hurtado, Esther Caparrós, Rocío García‐Villalba, Alicia Marín, Pedro Zapater, Fabián Tarín, José M. González‐Navajas, Francisco A. Tomás‐Barberán, Rubén Francés
Publikováno v:
Hepatology Communications, Vol 2, Iss 12, Pp 1610-1623 (2018)
Intestinal permeability to translocation of bacterial products is increased in cirrhosis. Regulatory T cells (Tregs) remain central to the interplay between the host and microbial milieu. We propose that Tregs are involved in promoting gut barrier in
Externí odkaz:
https://doaj.org/article/82b2a6aa3b91499fb88b47fdab865909
Autor:
Esther Caparrós, Oriol Juanola, Isabel Gómez-Hurtado, Amaya Puig-Kroger, Paula Piñero, Pedro Zapater, Raquel Linares, Fabián Tarín, Sebastián Martínez-López, Jordi Gracia-Sancho, José M. González-Navajas, Rubén Francés
Publikováno v:
Cells, Vol 9, Iss 5, p 1227 (2020)
Hepatic immune function is compromised during cirrhosis. This study investigated the immune features of liver sinusoidal endothelial cells (LSECs) in two experimental models of cirrhosis. Dendritic cells, hepatic macrophages, and LSECs were isolated
Externí odkaz:
https://doaj.org/article/bb98d19e0bff42cbb7320aff21933b7a