Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jose M. Fernández-Real"'
Autor:
María Pardo, Ana B. Crujeiras, María Amil, Zaida Aguera, Susana Jiménez-Murcia, Rosa Baños, Cristina Botella, Rafael de la Torre, Xavier Estivill, Ana B. Fagundo, Jose M. Fernández-Real, José C. Fernández-García, Gema Fruhbeck, Javier Gómez-Ambrosi, Roser Rodríguez, Francisco J. Tinahones, Fernando Fernández-Aranda, Felipe F. Casanueva
Publikováno v:
International Journal of Endocrinology, Vol 2014 (2014)
FNDC5/irisin has been recently postulated as beneficial in the treatment of obesity and diabetes because it is induced in muscle by exercise, increasing energy expenditure. However, recent reports have shown that WAT also secretes irisin and that cir
Externí odkaz:
https://doaj.org/article/e4b4318205dc47568c4ef8933bf97ce4
Autor:
Aina Lluch, Jèssica Latorre, Núria Oliveras-Cañellas, Ana Fernández-Sánchez, José M. Moreno-Navarrete, Anna Castells-Nobau, Ferran Comas, Maria Buxò, José I. Rodríguez-Hermosa, María Ballester, Isabel Espadas, Alejandro Martín-Montalvo, Birong Zhang, You Zhou, Ralph Burkhardt, Marcus Höring, Gerhard Liebisch, Ainara Castellanos-Rubio, Izortze Santin, Asha Kar, Markku Laakso, Päivi Pajukanta, Vesa M. Olkkonen, José M. Fernández-Real, Francisco J. Ortega
Publikováno v:
Molecular Metabolism, Vol 90, Iss , Pp 102040- (2024)
Background: Long non-coding RNAs (lncRNAs) can perform tasks of key relevance in fat cells, contributing, when defective, to the burden of obesity and its sequelae. Here, scrutiny of adipose tissue transcriptomes before and after bariatric surgery (G
Externí odkaz:
https://doaj.org/article/ca620d31a1364335831107541b0e2f56
Autor:
Aina Lluch, Jessica Latorre, Angela Serena-Maione, Isabel Espadas, Estefanía Caballano-Infantes, José M. Moreno-Navarrete, Núria Oliveras-Cañellas, Wifredo Ricart, María M. Malagón, Alejandro Martin-Montalvo, Walter Birchmeier, Witold Szymanski, Johannes Graumann, María Gómez-Serrano, Elena Sommariva, José M. Fernández-Real, Francisco J. Ortega
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Plakophilin-2 (PKP2) is a key component of desmosomes, which, when defective, is known to promote the fibro-fatty infiltration of heart muscle. Less attention has been given to its role in adipose tissue. We report here that levels of PKP2 s
Externí odkaz:
https://doaj.org/article/c9aab534331a4f3fa90b32b90c48e65f
Autor:
Sarah, Sauchelli, Susana, Jiménez-Murcia, Jose C, Fernández-García, Lourdes, Garrido-Sánchez, Francisco J, Tinahones, Felipe F, Casanueva, Rosa M, Baños, Cristina, Botella, Ana B, Crujeiras, Rafael, de la Torre, Jose M, Fernández-Real, Gema, Frühbeck, Roser, Granero, Francisco J, Ortega, Amaia, Rodríguez, Stephan, Zipfel, Katrin E, Giel, Jose M, Menchón, Fernando, Fernández-Aranda
Publikováno v:
European eating disorders review : the journal of the Eating Disorders Association. 24(6)
The current study examined the relationship between plasma orexin-A and sleep in obesity. Concentrations of orexin-A and sleep were evaluated in 26 obese, 40 morbid obese and 32 healthy-weight participants. The sleep monitor Actiwatch AW7 and the Pit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9190bb71a56150719ab005938ba10447
https://pubmed.ncbi.nlm.nih.gov/27785902
https://pubmed.ncbi.nlm.nih.gov/27785902
Autor:
Aina Lluch, Sonia R. Veiga, Jèssica Latorre, José M. Moreno-Navarrete, Núria Bonifaci, Van Dien Nguyen, You Zhou, Marcus Höring, Gerhard Liebisch, Vesa M. Olkkonen, David Llobet-Navas, George Thomas, Ruth Rodríguez-Barrueco, José M. Fernández-Real, Sara C. Kozma, Francisco J. Ortega
Publikováno v:
JCI Insight, Vol 7, Iss 14 (2022)
The ribosomal protein S6 kinase 1 (S6K1) is a relevant effector downstream of the mammalian target of rapamycin complex 1 (mTORC1), best known for its role in the control of lipid homeostasis. Consistent with this, mice lacking the S6k1 gene have a d
Externí odkaz:
https://doaj.org/article/fd58ace89a53441583d2cf1df43a3a08
A microRNA Cluster Controls Fat Cell Differentiation and Adipose Tissue Expansion By Regulating SNCG
Autor:
Ruth Rodríguez‐Barrueco, Jessica Latorre, Laura Devis‐Jáuregui, Aina Lluch, Nuria Bonifaci, Francisco J. Llobet, Mireia Olivan, Laura Coll‐Iglesias, Katja Gassner, Meredith L. Davis, José M. Moreno‐Navarrete, Anna Castells‐Nobau, Laura Plata‐Peña, Miki Dalmau‐Pastor, Marcus Höring, Gerhard Liebisch, Vesa M. Olkkonen, Maria Arnoriaga‐Rodríguez, Wifredo Ricart, José M. Fernández‐Real, José M. Silva, Francisco J. Ortega, David Llobet‐Navas
Publikováno v:
Advanced Science, Vol 9, Iss 4, Pp n/a-n/a (2022)
Abstract The H19X‐encoded miR‐424(322)/503 cluster regulates multiple cellular functions. Here, it is reported for the first time that it is also a critical linchpin of fat mass expansion. Deletion of this miRNA cluster in mice results in obesity
Externí odkaz:
https://doaj.org/article/e3f63b7bc662455caa34ba1b1fa999a2
Autor:
Jèssica Latorre, Francisco J. Ortega, Laura Liñares-Pose, José M. Moreno-Navarrete, Aina Lluch, Ferran Comas, Núria Oliveras-Cañellas, Wifredo Ricart, Marcus Höring, You Zhou, Gerhard Liebisch, P.A. Nidhina Haridas, Vesa M. Olkkonen, Miguel López, José M. Fernández-Real
Publikováno v:
EBioMedicine, Vol 53, Iss , Pp - (2020)
Background: While the impact of metformin in hepatocytes leads to fatty acid (FA) oxidation and decreased lipogenesis, hepatic microRNAs (miRNAs) have been associated with fat overload and impaired metabolism, contributing to the pathogenesis of non-
Externí odkaz:
https://doaj.org/article/6aa13ae9f1304a82a59ada019901c3cd
Autor:
Antoni Pastor, Fernando Fernández-Aranda, Montserrat Fitó, Susana Jiménez-Murcia, Cristina Botella, Jose M Fernández-Real, Gema Frühbeck, Francisco J Tinahones, Ana B Fagundo, Joan Rodriguez, Zaida Agüera, Klaus Langohr, Felipe F Casanueva, Rafael de la Torre
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148734 (2016)
The endocannabinoid (eCB) system can promote food intake by increasing odor detection in mice. The eCB system is over-active in human obesity. Our aim is to measure circulating eCB concentrations and olfactory capacity in a human sample that includes
Externí odkaz:
https://doaj.org/article/70a1aff583bb431f8d86b0d3544c5a04
Autor:
Nuria Mallorquí-Bagué, Ana B Fagundo, Susana Jimenez-Murcia, Rafael de la Torre, Rosa M Baños, Cristina Botella, Felipe F Casanueva, Ana B Crujeiras, Jose C Fernández-García, Jose M Fernández-Real, Gema Frühbeck, Roser Granero, Amaia Rodríguez, Iris Tolosa-Sola, Francisco J Ortega, Francisco J Tinahones, Eva Alvarez-Moya, Cristian Ochoa, Jose M Menchón, Fernando Fernández-Aranda
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163901 (2016)
INTRODUCTION:Addictions are associated with decision making impairments. The present study explores decision making in Substance use disorder (SUD), Gambling disorder (GD) and Obesity (OB) when assessed by Iowa Gambling Task (IGT) and compares them w
Externí odkaz:
https://doaj.org/article/b4982958df7a46d7a8eee2fcba027462
Autor:
Ana B Fagundo, Susana Jiménez-Murcia, Cristina Giner-Bartolomé, Mohammed Anisul Islam, Rafael de la Torre, Antoni Pastor, Felipe F Casanueva, Ana B Crujeiras, Roser Granero, Rosa Baños, Cristina Botella, Jose M Fernández-Real, Gema Frühbeck, Javier Gómez-Ambrosi, José M Menchón, Francisco J Tinahones, Fernando Fernández-Aranda
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130319 (2015)
The prefrontal (PFC) and orbitofrontal cortex (OFC) appear to be associated with both executive functions and olfaction. However, there is little data relating olfactory processing and executive functions in humans. The present study aimed at explori
Externí odkaz:
https://doaj.org/article/b83b2d3fafa5438c9a08185d10a1d7af