Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jose M Herranz"'
Autor:
Eduardo H. Gilglioni, Ao Li, Wadsen St-Pierre-Wijckmans, Tzu-Keng Shen, Israel Pérez-Chávez, Garnik Hovhannisyan, Michela Lisjak, Javier Negueruela, Valerie Vandenbempt, Julia Bauzá-Martinez, Jose M. Herranz, Daria Ezeriņa, Stéphane Demine, Zheng Feng, Thibaut Vignane, Lukas Otero Sanchez, Flavia Lambertucci, Alena Prašnická, Jacques Devière, David C. Hay, Jose A. Encinar, Sumeet Pal Singh, Joris Messens, Milos R. Filipovic, Hayley J. Sharpe, Eric Trépo, Wei Wu, Esteban N. Gurzov
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Fat accumulation, de novo lipogenesis, and glycolysis are key drivers of hepatocyte reprogramming and the consequent metabolic dysfunction-associated steatotic liver disease (MASLD). Here we report that obesity leads to dysregulated expressi
Externí odkaz:
https://doaj.org/article/47d15d12bd9c4154ade149ceeddbddb9
Autor:
Natalia Pydyn, Anna Ferenc, Katarzyna Trzos, Ewelina Pospiech, Mateusz Wilamowski, Olga Mucha, Piotr Major, Justyna Kadluczka, Pedro M. Rodrigues, Jesus M. Banales, Jose M. Herranz, Matias A. Avila, Tomasz Hutsch, Piotr Malczak, Dorota Radkowiak, Andrzej Budzynski, Jolanta Jura, Jerzy Kotlinowski
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 6, Pp 887-906 (2024)
Background & Aims: Hepatic fibrosis is characterized by enhanced deposition of extracellular matrix (ECM), which results from the wound healing response to chronic, repeated injury of any etiology. Upon injury, hepatic stellate cells (HSCs) activate
Externí odkaz:
https://doaj.org/article/a8639a414f0d4d65bfedfeb983af94c3
Autor:
Leticia Colyn, Gloria Alvarez-Sola, M. Ujue Latasa, Iker Uriarte, Jose M. Herranz, Maria Arechederra, George Vlachogiannis, Colin Rae, Antonio Pineda-Lucena, Andrea Casadei-Gardini, Federica Pedica, Luca Aldrighetti, Angeles López-López, Angeles López-Gonzálvez, Coral Barbas, Sergio Ciordia, Sebastiaan M. Van Liempd, Juan M. Falcón-Pérez, Jesus Urman, Bruno Sangro, Silve Vicent, Maria J. Iraburu, Felipe Prosper, Leonard J. Nelson, Jesus M. Banales, Maria Luz Martinez-Chantar, Jose J. G. Marin, Chiara Braconi, Christian Trautwein, Fernando J. Corrales, F. Javier Cubero, Carmen Berasain, Maite G. Fernandez-Barrena, Matias A. Avila
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-18 (2022)
Abstract Background Cholangiocarcinoma (CCA) is still a deadly tumour. Histological and molecular aspects of thioacetamide (TAA)-induced intrahepatic CCA (iCCA) in rats mimic those of human iCCA. Carcinogenic changes and therapeutic vulnerabilities i
Externí odkaz:
https://doaj.org/article/278c7dac66c24c988487ac905912005b
Autor:
Marta Alonso-Peña, Ricardo Espinosa-Escudero, Heike M. Hermanns, Oscar Briz, Jose M. Herranz, Carmen Garcia-Ruiz, Jose C. Fernandez-Checa, Javier Juamperez, Matias Avila, Josepmaria Argemi, Ramon Bataller, Javier Crespo, Maria J. Monte, Andreas Geier, Elisa Herraez, Jose J. G. Marin
Publikováno v:
Cells, Vol 11, Iss 24, p 3983 (2022)
Bile acid (BA) synthesis from cholesterol by hepatocytes is inhibited by inflammatory cytokines. Whether liver inflammation also affects BA side chain shortening and conjugation was investigated. In human liver cell lines (IHH, HepG2, and HepaRG), ag
Externí odkaz:
https://doaj.org/article/afa68f19897a4a61904c36422a1bf94e
Autor:
Josepmaria Argemi, Komal Kedia, Marina A. Gritsenko, Ana Clemente-Sanchez, Aliya Asghar, Jose M. Herranz, Zhang-Xu Liu, Stephen R. Atkinson, Richard D. Smith, Trina M. Norden-Krichmar, Le Z. Day, Andrew Stolz, John A. Tayek, Ramon Bataller, Timothy R. Morgan, Jon M. Jacobs
Publikováno v:
The American Journal of Pathology. 192:1658-1669
Alcohol-associated hepatitis (AH) is a form of liver failure with high short-term mortality. Recent studies have shown that defective function of hepatocyte nuclear factor 4 alpha (HNF4a) and systemic inflammation are major disease drivers of AH. Pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fe3b65b19b8fcbfb473c24435922b8c
https://doi.org/10.1016/j.ajpath.2022.08.009
https://doi.org/10.1016/j.ajpath.2022.08.009
Akademický článek
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Autor:
Naroa Goikoetxea-Usandizaga, Miren Bravo, Leire Egia-Mendikute, Leticia Abecia, Marina Serrano-Maciá, Rocío G. Urdinguio, Marc Clos-García, Rubén Rodríguez-Agudo, Raquel Araujo-Legido, Lucía López-Bermudo, Teresa C. Delgado, Sofía Lachiondo-Ortega, Irene González-Recio, Clàudia Gil-Pitarch, Ainize Peña-Cearra, Jorge Simón, Raquel Benedé-Ubieto, Silvia Ariño, Jose M. Herranz, Mikel Azkargorta, Julio Salazar-Bermeo, Nuria Martí, Marta Varela-Rey, Juan M. Falcón-Pérez, Óscar Lorenzo, Rubén Nogueiras, Félix Elortza, Yulia A. Nevzorova, Francisco J. Cubero, Domingo Saura, Luis Alfonso Martínez-Cruz, Guadalupe Sabio, Asís Palazón, Pau Sancho-Bru, Natalia Elguezabal, Mario F. Fraga, Matías A. Ávila, Ramón Bataller, José J.G. Marín, Franz Martín, María Luz Martínez-Chantar
Publikováno v:
Hepatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::036824987a2bb75607ee1667c2171682
https://doi.org/10.1097/hep.0000000000000303
https://doi.org/10.1097/hep.0000000000000303
Autor:
Julen Oyarzabal, Robert Arnes-Benito, Leticia Colyn, Jose J.G. Marin, Jose M Herranz, Maite G. Fernandez-Barrena, María J. Iraburu, Maria Francesconi, Gloria Alvarez-Sola, Meritxell Huch, Leonard J Nelson, Francisco Javier Cubero, Matías A. Avila, Altaf A. Dar, Jesus M. Banales, Iker Uriarte, Mikel Ruiz de Gauna, Simone Carotti, Jesús Urman, Sergio Morini, María L. Martínez-Chantar, Chaobo Chen, Marina Bárcena-Varela, Eva Santamaría, Andrea Casadei-Gardini, Christian Trautwein, Patricia Aspichueta, Alvaro Santos-Laso, Carmen Berasain, Felipe Prosper, Bruno Sangro, John M Patino, Matteo Canale, Mehdi Nosrati, María Arechederra, M. Ujue Latasa
Publikováno v:
Hepatology. 73:2380-2396
Background and aims Cholangiocarcinoma (CCA) is a devastating disease often detected at advanced stages when surgery cannot be performed. Conventional and targeted systemic therapies perform poorly, and therefore effective drugs are urgently needed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81ae64ca991d1997b859d84eab9eef5
https://doi.org/10.1002/hep.31642
https://doi.org/10.1002/hep.31642
Autor:
Joan Ferrer Obiol, Jose M. Herranz, Josephine R. Paris, James R. Whiting, Julio Rozas, Marta Riutort, Jacob González-Solís
Publikováno v:
Molecular Phylogenetics and Evolution. 179:107671
Speciation is a continuous and complex process shaped by the interaction of numerous evolutionary forces. Despite the continuous nature of the speciation process, the implementation of conservation policies relies on the delimitation of species and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4070d87e8a1ec3af7eee98ab390243e9
https://doi.org/10.1016/j.ympev.2022.107671
https://doi.org/10.1016/j.ympev.2022.107671
Autor:
Cristina Saldaña, Iranzu González-Borja, David Guerrero-Setas, Ignacio Fernandez-Urien, María Angeles Sotés Elizalde, Jose M Herranz, Waldemar Patkowski, Francisco Javier Cubero, Irene Amat, Ana Purroy, María Rullán, Daniel Oyón, Gorka Alkorta-Aranburu, Carmen Berasain, Krzysztof Zieniewicz, Marcin Krawczyk, Lucía Zabalza, Juan J. Vila, Matías A. Avila, Piotr Milkiewicz, Leonard J Nelson, Maria Del Rosario Mercado, Vanesa Jusué, D. Ruiz-Clavijo, M. Ujue Latasa, Isabel Gil, Maite G. Fernandez-Barrena, Cruz Zazpe, María Arechederra, Bruno Sangro, Jesús Urman, Juan Carrascosa
Publikováno v:
Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
instname
instname
Objective: despite significant progresses in imaging and pathological evaluation, early differentiation between benign and malignant biliary strictures remains challenging. Endoscopic retrograde cholangiopancreatography (ERCP) is used to investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2176e8557a33f165616e0a9d39f6068
https://pubmed.ncbi.nlm.nih.gov/34285068
https://pubmed.ncbi.nlm.nih.gov/34285068