Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Jose M G Vilar"'
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18622 (2011)
Bacteria spend most of their lifetime in non-growing states which allow them to survive extended periods of stress and starvation. When environments improve, they must quickly resume growth to maximize their share of limited nutrients. Cells with hig
Externí odkaz:
https://doaj.org/article/579962e6641c4ff1bd3f089745ec9487
Autor:
Leonor Saiz, Jose M G Vilar
Publikováno v:
PLoS ONE, Vol 2, Iss 4, p e355 (2007)
Protein-DNA complexes with loops play a fundamental role in a wide variety of cellular processes, ranging from the regulation of DNA transcription to telomere maintenance. As ubiquitous as they are, their precise in vivo properties and their integrat
Externí odkaz:
https://doaj.org/article/567b7e333d834fbe8806be0b6c21d4cf
Publikováno v:
PLoS Computational Biology, Vol 2, Iss 1, p e3 (2006)
The TGF-beta pathway plays a central role in tissue homeostasis and morphogenesis. It transduces a variety of extracellular signals into intracellular transcriptional responses that control a plethora of cellular processes, including cell growth, apo
Externí odkaz:
https://doaj.org/article/963f6c482b694bf4971f644433520373
Autor:
Jose M. G. Vilar, Leonor Saiz
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract The prevalent one-dimensional alignment of genomic signals to a reference landmark is a cornerstone of current methods to study transcription and its DNA-dependent processes but it is prone to mask potential relations among multiple DNA elem
Externí odkaz:
https://doaj.org/article/c4432208ee6e4b59a2df061117c6f2d3
Autor:
Jose M. G. Vilar, Leonor Saiz
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract The dynamic characterization of the COVID-19 outbreak is critical to implement effective actions for its control and eradication but the information available at a global scale is not sufficiently reliable to be used directly. Here, we devel
Externí odkaz:
https://doaj.org/article/ac0984a696b64e4ea31d3b8130c6e41a
Autor:
Attila Gabor, Marco Tognetti, Alice Driessen, Jovan Tanevski, Baosen Guo, Wencai Cao, He Shen, Thomas Yu, Verena Chung, Single Cell Signaling in Breast Cancer DREAM Consortium members, Bernd Bodenmiller, Julio Saez‐Rodriguez, Augustinas Prusokas, Alidivinas Prusokas, Renata Retkute, Anand Rajasekar, Karthik Raman, Malvika Sudhakar, Raghunathan Rengaswamy, Edward S.C. Shih, Min‐jeong Kim, Changje Cho, Dohyang Kim, Hyeju Oh, Jinseub Hwang, Kim Jongtae, Yeongeun Nam, Sanghoo Yoon, Taeyong Kwon, Kyeongjun Lee, Sarika Chaudhary, Nehal Sharma, Shreya Bande, Gao Gao fan zhu Cankut Cubuk, Pelin Gundogdu, Joaquin Dopazo, Kinza Rian, Carlos Loucera, Matias M Falco, Martin Garrido‐Rodriguez, Maria Peña‐Chilet, Huiyuan Chen, Gabor Turu, Laszlo Hunyadi, Adam Misak, Lisheng Zhou, Xiaoqing Jiang, Pieta Zhang, Aakansha Rai, Rintu Kutum, Sadhna Rana, Rajgopal Srinivasan, Swatantra Pradhan, James Li, Vladimir Bajic, Christophe Van Neste, Didier Barradas‐bautista, Somayah Abdullah Albarade, Igor Nikolskiy, Musalula Sinkala, Duc Tran, Hung Nguyen, Tin Nguyen, Alexander Wu, Benjamin DeMeo, Brian Hie, Rohit Singh, Jiwei Liu, Xueer Chen, Leonor Saiz, Jose M. G Vilar, Peng Qiu, Akash Gosain, Anjali Dhall, Dinesh Bajaj, Harpreet Kaur, Krishna Bagaria, Mayank Chauhan, Neelam Sharma, Gajendra Raghava, Sumeet Patiyal, Jianye Hao, Jiajie Peng, Shangyi Ning, Yi Ma, Zhongyu Wei, Atte Aalto, Jorge Goncalves, Laurent Mombaerts, Xinnan Dai, Jie Zheng, Piyushkumar Mundra, Fan Xu, Jie Wang, Krishna Kant Singh, Mingyu Lee
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 10, Pp 1-16 (2021)
Abstract Recent technological developments allow us to measure the status of dozens of proteins in individual cells. This opens the way to understand the heterogeneity of complex multi‐signaling networks across cells and cell types, with important
Externí odkaz:
https://doaj.org/article/bcd5b154a6e240949fe3c514a36f69b2
Autor:
Jose M. G. Vilar, Leonor Saiz
Publikováno v:
Royal Society Open Science, Vol 8, Iss 10 (2021)
Assessing a potential resurgence of an epidemic outbreak with certainty is as important as it is challenging. The low number of infectious individuals after a long regression, and the randomness associated with it, makes it difficult to ascertain whe
Externí odkaz:
https://doaj.org/article/cd3c5c9143cd4c62baf60a8e15076c8f
The disassembly of misfolded protein aggregates is a requirement for the proper functioning of cells. It has implications in multiple neuropathologies, such as Alzheimer’s and Parkinson’s diseases. The active unbundling of fibrillar aggregates ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7c98f0c3f7b0c88a4b26070a02ae0f6
https://doi.org/10.1101/2023.05.24.542046
https://doi.org/10.1101/2023.05.24.542046
Autor:
Jose M. G. Vilar, Leonor Saiz
Systems like the prototypicallacoperon can reliably hold the repression of transcription upon DNA replication across cell cycles with just ten repressor molecules per cell and, in addition, behave as if they were at equilibrium. The origin of this ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e54abf385dcefe5a768da8f69301e34
https://doi.org/10.1101/2023.03.31.535089
https://doi.org/10.1101/2023.03.31.535089
Autor:
Leonor Saiz, Jose M. G. Vilar
The prevalent one-dimensional alignment of genomic signals to a reference landmark is a cornerstone of current methods to study transcription and its DNA-dependent processes but it is prone to mask potential relations among multiple DNA elements. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c7e726e524c206855db8554d90ba859
https://doi.org/10.1101/2021.09.02.458606
https://doi.org/10.1101/2021.09.02.458606