Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Jose M G Izarzugaza"'
Autor:
Enrique Audain, Anna Wilsdon, Jeroen Breckpot, Jose M G Izarzugaza, Tomas W Fitzgerald, Anne-Karin Kahlert, Alejandro Sifrim, Florian Wünnemann, Yasset Perez-Riverol, Hashim Abdul-Khaliq, Mads Bak, Anne S Bassett, D Woodrow Benson, Felix Berger, Ingo Daehnert, Koenraad Devriendt, Sven Dittrich, Piers Ef Daubeney, Vidu Garg, Karl Hackmann, Kirstin Hoff, Philipp Hofmann, Gregor Dombrowsky, Thomas Pickardt, Ulrike Bauer, Bernard D Keavney, Sabine Klaassen, Hans-Heiner Kramer, Christian R Marshall, Dianna M Milewicz, Scott Lemaire, Joseph S Coselli, Michael E Mitchell, Aoy Tomita-Mitchell, Siddharth K Prakash, Karl Stamm, Alexandre F R Stewart, Candice K Silversides, Reiner Siebert, Brigitte Stiller, Jill A Rosenfeld, Inga Vater, Alex V Postma, Almuth Caliebe, J David Brook, Gregor Andelfinger, Matthew E Hurles, Bernard Thienpont, Lars Allan Larsen, Marc-Phillip Hitz
Publikováno v:
PLoS Genetics, Vol 17, Iss 9, p e1009809 (2021)
[This corrects the article DOI: 10.1371/journal.pgen.1009679.].
Externí odkaz:
https://doaj.org/article/ee3c8898ef0a43729adf837c70afaa5a
Autor:
Enrique Audain, Anna Wilsdon, Jeroen Breckpot, Jose M G Izarzugaza, Tomas W Fitzgerald, Anne-Karin Kahlert, Alejandro Sifrim, Florian Wünnemann, Yasset Perez-Riverol, Hashim Abdul-Khaliq, Mads Bak, Anne S Bassett, D Woodrow Benson, Felix Berger, Ingo Daehnert, Koenraad Devriendt, Sven Dittrich, Piers Ef Daubeney, Vidu Garg, Karl Hackmann, Kirstin Hoff, Philipp Hofmann, Gregor Dombrowsky, Thomas Pickardt, Ulrike Bauer, Bernard D Keavney, Sabine Klaassen, Hans-Heiner Kramer, Christian R Marshall, Dianna M Milewicz, Scott Lemaire, Joseph S Coselli, Michael E Mitchell, Aoy Tomita-Mitchell, Siddharth K Prakash, Karl Stamm, Alexandre F R Stewart, Candice K Silversides, Reiner Siebert, Brigitte Stiller, Jill A Rosenfeld, Inga Vater, Alex V Postma, Almuth Caliebe, J David Brook, Gregor Andelfinger, Matthew E Hurles, Bernard Thienpont, Lars Allan Larsen, Marc-Phillip Hitz
Publikováno v:
PLoS Genetics, Vol 17, Iss 7, p e1009679 (2021)
Numerous genetic studies have established a role for rare genomic variants in Congenital Heart Disease (CHD) at the copy number variation (CNV) and de novo variant (DNV) level. To identify novel haploinsufficient CHD disease genes, we performed an in
Externí odkaz:
https://doaj.org/article/92067f3613e64d39b29f8fdaa8154ba8
Autor:
Nicolai Juul Birkbak, Bose Kochupurakkal, Jose M G Izarzugaza, Aron C Eklund, Yang Li, Joyce Liu, Zoltan Szallasi, Ursula A Matulonis, Andrea L Richardson, J Dirk Iglehart, Zhigang C Wang
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80023 (2013)
BackgroundIncreased number of single nucleotide substitutions is seen in breast and ovarian cancer genomes carrying disease-associated mutations in BRCA1 or BRCA2. The significance of these genome-wide mutations is unknown. We hypothesize genome-wide
Externí odkaz:
https://doaj.org/article/af39aee1554b495da94db92c355a9275
Autor:
Morten Bo Johansen, Jose M G Izarzugaza, Søren Brunak, Thomas Nordahl Petersen, Ramneek Gupta
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68370 (2013)
We have developed a sequence conservation-based artificial neural network predictor called NetDiseaseSNP which classifies nsSNPs as disease-causing or neutral. Our method uses the excellent alignment generation algorithm of SIFT to identify related s
Externí odkaz:
https://doaj.org/article/3c3048c96d5a448e9b079b168e203ba2
Von Frey testing revisited: Provision of an online algorithm for improved accuracy of 50% thresholds
Autor:
Thomas Hansen, Jes Olesen, Mikkel Ammentorp Storm, Rie Bager Hansen, Michael H. Ossipov, David Møbjerg Kristensen, Frank Porreca, Sarah L Christensen, Jose M. G. Izarzugaza
Publikováno v:
Christensen, S L, Hansen, R B, Storm, M A, Olesen, J, Hansen, T F, Ossipov, M, Izarzugaza, J M G, Porreca, F & Kristensen, D M 2020, ' Von Frey testing revisited: Provision of an online algorithm for improved accuracy of 50% thresholds ', European Journal of Pain, vol. 24, no. 4, pp. 783-790 . https://doi.org/10.1002/ejp.1528
Christensen, S L, Hansen, R B, Storm, M A, Olesen, J, Hansen, T F, Ossipov, M, Izarzugaza, J M G, Porreca, F & Kristensen, D M 2020, ' Von Frey testing revisited: Provision of an online algorithm for improved accuracy of 50% thresholds ', European Journal of Pain, vol. 24, pp. 783–790 . https://doi.org/10.1002/ejp.1528
Christensen, S L, Hansen, R B, Storm, M A, Olesen, J, Hansen, T F, Ossipov, M, Izarzugaza, J M G, Porreca, F & Kristensen, D M 2020, ' Von Frey testing revisited: Provision of an online algorithm for improved accuracy of 50% thresholds ', European Journal of Pain, vol. 24, pp. 783–790 . https://doi.org/10.1002/ejp.1528
Background: In the pain field, it is essential to quantify nociceptive responses. The response to the application of von Frey filaments to the skin measures tactile sensitivity and is a surrogate marker of allodynia in states of peripheral and/or cen
Autor:
Karine Audouze, Jose M. G. Izarzugaza, Sonny Kim Kjærulff, Søren Brunak, Jose Alejandro Romero Herrera, Anne Tjønneland, Kim Overvad, Li Jiang, Thorkild I. A. Sørensen, Lars Ängquist, Jytte Halkjær
Publikováno v:
Jiang, L, Audouze, K, Romero Herrera, J A, Ängquist, L H, Kjærulff, S K, Izarzugaza, J M G, Tjønneland, A, Halkjær, J, Overvad, K, Sørensen, T I A & Brunak, S 2020, ' Conflicting associations between dietary patterns and changes of anthropometric traits across subgroups of middle-aged women and men ', Clinical Nutrition, vol. 39, no. 1, pp. 265-275 . https://doi.org/10.1016/j.clnu.2019.02.003
BACKGROUND: Individuals respond differently to dietary intake leading to different associations between diet and traits. Most studies have investigated large cohorts without subgrouping them.OBJECTIVE: The purpose was to identify non-uniform associat
Autor:
William W. Agace, Tune H. Pers, Gareth-Rhys Jones, Lene Riis, Fenton Tm, Henrik Loft Jakobsen, A M Mowat, Peter Bjørn Jørgensen, Søren Brunak, Ole Haagen Nielsen, L. Wulff, Jose M. G. Izarzugaza, Calum C. Bain, Belling Kg, Julien Vandamme, Gwo-Tzer Ho, Jimmy Tsz Hang Lee
Subsets of mononuclear phagocytes, including macrophages and classical dendritic cells (cDC), are highly heterogeneous in peripheral tissues such as the intestine, with each subset playing distinct roles in immune responses. Understanding this comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0119df15112fc311b4e379b9c835a4a
https://doi.org/10.1101/2021.03.28.437379
https://doi.org/10.1101/2021.03.28.437379
Autor:
Jose Alejandro Romero Herrera, Niels Jørgensen, Anne Kirstine Bang, Søren Brunak, Jose M. G. Izarzugaza, Lærke Priskorn
Publikováno v:
Herrera, J A R, Bang, A K, Priskorn, L, Izarzugaza, J M G, Brunak, S & Jørgensen, N 2021, ' Semen quality and waiting time to pregnancy explored using Association Mining ', Andrology, vol. 9, no. 2, pp. 577-587 . https://doi.org/10.1111/andr.12924
Romero Herrera, J A, Bang, A K, Priskorn, L, Izarzugaza, J M G, Brunak, S & Jørgensen, N 2021, ' Semen quality and waiting time to pregnancy explored using association mining ', Andrology, vol. 9, no. 2, pp. 577-587 . https://doi.org/10.1111/andr.12924
Romero Herrera, J A, Bang, A K, Priskorn, L, Izarzugaza, J M G, Brunak, S & Jørgensen, N 2021, ' Semen quality and waiting time to pregnancy explored using association mining ', Andrology, vol. 9, no. 2, pp. 577-587 . https://doi.org/10.1111/andr.12924
Background Assessment of semen quality is a key pillar in the evaluation of men from infertile couples. Usually, semen parameters are interpreted individually because the interactions between parameters are difficult to account for. Objectives To det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58c17914aa7b84a71bffe3ee3ba2d552
https://orbit.dtu.dk/en/publications/ceca9177-b21a-4198-b24e-78037bc44629
https://orbit.dtu.dk/en/publications/ceca9177-b21a-4198-b24e-78037bc44629
Autor:
Gregor Dombrowsky, Marc-Phillip Hitz, Hashim Abdul-Khaliq, Felix Berger, Piers E.F. Daubeney, Ingo Daehnert, Lars Allan Larsen, Michael E. Mitchell, Bernard Keavney, Mads Bak, Dianna M. Milewicz, Sven Dittrich, Philipp Hofmann, Kirstin Hoff, Woody D Benson, Hans-Heiner Kramer, Sabine Klaassen, Karl Hackmann, Siddharth K. Prakash, Brigitte Stiller, Aoy Tomita-Mitchell, Florian Wuennemann, Inga Vater, Christian R. Marshall, Anna Wilsdon, Alejandro Sifrim, Reiner Siebert, Thomas Pickardt, Scott Lemaire, Koenraad Devriendt, Joe Coselli, Almuth Caliebe, Enrique Audain, Karl Stamm, Kahlert Anne-Karin, Tomas W Fitzgerald, Jill A. Rosenfeld, Matthew E. Hurles, Alex V. Postma, Candice K. Silversides, Yasset Perez-Riverol, Jeroen Breckpot, John W. Belmont, U.M.M. Bauer, Gregor Andelfinger, Anne S. Bassett, Vidu Garg, Alexandre F.R. Stewart, David Brook, Bernard Thienpont, Jose M. G. Izarzugaza
Congenital Heart Disease (CHD) affects approximately 7-9 children per 1000 live births. Numerous genetic studies have established a role for rare genomic variants at the copy number variation (CNV) and single nucleotide variant level. In particular,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efcf7c3ec6761a9db19fadfeb46c6811
http://edoc.mdc-berlin.de/19088/7/19088suppl.zip
http://edoc.mdc-berlin.de/19088/7/19088suppl.zip
Autor:
Daniel B. Andersen, Jose M. G. Izarzugaza, Rune E. Kuhre, Stella Feng Sheng Xu, Jens J. Holst
Publikováno v:
Acta Physiologica. 229
AIM It is debated whether the inhibition of glucagon secretion by glucose results from direct effects of glucose on the α-cell (intrinsic regulation) or by paracrine effects exerted by beta- or delta-cell products. METHODS To study this in a more ph