Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Jose M C, Tubio"'
Autor:
Yoel Z. Betancor, Miriam Ferreiro-Pantín, Urbano Anido-Herranz, Mar Fuentes-Losada, Luis León-Mateos, Silvia Margarita García-Acuña, Vanessa Vaamonde-Rodríguez, Beatriz García-Pinel, Víctor Cebey-López, Rosa Villaverde-Viaño, Helena Lombardía-Rodríguez, Martin Kotrulev, Natalia Fernández-Díaz, Iria Gomez-Tourino, Carlos Fernández-Baltar, Jorge García-González, Jose M. C. Tubio, Rafael López-López, Juan Ruiz-Bañobre
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
In the advanced renal cell carcinoma (RCC) scenario, there are no consistent biomarkers to predict the clinical benefit patients derived from immune checkpoint blockade (ICB). Taking this into consideration, herein, we conducted a retrospective study
Externí odkaz:
https://doaj.org/article/3df50f215da44f60a777ca651a4ba236
Autor:
Pablo Bousquets-Muñoz, Ander Díaz-Navarro, Ferran Nadeu, Ana Sánchez-Pitiot, Sara López-Tamargo, Shimin Shuai, Milagros Balbín, Jose M. C. Tubio, Sílvia Beà, Jose I. Martin-Subero, Ana Gutiérrez-Fernández, Lincoln D. Stein, Elías Campo, Xose S. Puente
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-12 (2022)
Abstract Current somatic mutation callers are biased against repetitive regions, preventing the identification of potential driver alterations in these loci. We developed a mutation caller for repetitive regions, and applied it to study repetitive no
Externí odkaz:
https://doaj.org/article/5f0f3806b2a34e4faaa729f3e687de20
Autor:
Eva G. Álvarez, Jonas Demeulemeester, Paula Otero, Clemency Jolly, Daniel García-Souto, Ana Pequeño-Valtierra, Jorge Zamora, Marta Tojo, Javier Temes, Adrian Baez-Ortega, Bernardo Rodriguez-Martin, Ana Oitaben, Alicia L. Bruzos, Mónica Martínez-Fernández, Kerstin Haase, Sonia Zumalave, Rosanna Abal, Jorge Rodríguez-Castro, Aitor Rodriguez-Casanova, Angel Diaz-Lagares, Yilong Li, Keiran M. Raine, Adam P. Butler, Iago Otero, Atsushi Ono, Hiroshi Aikata, Kazuaki Chayama, Masaki Ueno, Shinya Hayami, Hiroki Yamaue, Kazuhiro Maejima, Miguel G. Blanco, Xavier Forns, Carmen Rivas, Juan Ruiz-Bañobre, Sofía Pérez-del-Pulgar, Raúl Torres-Ruiz, Sandra Rodriguez-Perales, Urtzi Garaigorta, Peter J. Campbell, Hidewaki Nakagawa, Peter Van Loo, Jose M. C. Tubio
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Hepatitis B virus (HBV) infection and DNA integration is a frequent cause of hepatocellular carcinoma (HCC), but the consequences of this process are not fully understood. Here the authors use whole-genome and long-read sequencing data from HCC patie
Externí odkaz:
https://doaj.org/article/9d6ae04fdf164e1683ea18005b4462b3
Autor:
Francesco Maura, Niccoló Bolli, Nicos Angelopoulos, Kevin J. Dawson, Daniel Leongamornlert, Inigo Martincorena, Thomas J. Mitchell, Anthony Fullam, Santiago Gonzalez, Raphael Szalat, Federico Abascal, Bernardo Rodriguez-Martin, Mehmet Kemal Samur, Dominik Glodzik, Marco Roncador, Mariateresa Fulciniti, Yu Tzu Tai, Stephane Minvielle, Florence Magrangeas, Philippe Moreau, Paolo Corradini, Kenneth C. Anderson, Jose M. C. Tubio, David C. Wedge, Moritz Gerstung, Hervé Avet-Loiseau, Nikhil Munshi, Peter J. Campbell
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Multiple myeloma evolves continuously. Here the authors chronologically reconstruct driver events in multiple myeloma, noting a limited repertoire of initiating driver events that shape the evolutionary trajectory of the disease.
Externí odkaz:
https://doaj.org/article/a38608a486ef471e8da57b4ab94d19b3
Autor:
Francesco Maura, Anna Dodero, Cristiana Carniti, Niccolò Bolli, Martina Magni, Valentina Monti, Antonello Cabras, Daniel Leongamornlert, Federico Abascal, Benjamin Diamond, Bernardo Rodriguez-Martin, Jorge Zamora, Adam Butler, Inigo Martincorena, Jose M. C. Tubio, Peter J. Campbell, Annalisa Chiappella, Giancarlo Pruneri, Paolo Corradini
Publikováno v:
Haematologica, Vol 106, Iss 11 (2020)
Nodal peripheral T-cell lymphoma not otherwise specified (PTCLNOS) remains a diagnosis encompassing a heterogenous group of PTCL cases not fitting criteria for more homogeneous subtypes. They are characterized by a poor clinical outcome when treated
Externí odkaz:
https://doaj.org/article/f4bd9da4003c40d290d653cd147b406f
Autor:
Miriam Ferreiro-Pantín, Urbano Anido-Herranz, Yoel Z. Betancor, Víctor Cebey-López, Luis León-Mateos, Jorge García-González, Silvia Margarita García-Acuña, Natalia Fernández-Díaz, Jose M. C. Tubio, Rafael López-López, Juan Ruiz-Bañobre
BackgroundIn the advanced urothelial carcinoma (aUC) scenario there are no consistent biomarkers to predict the benefit patients derived from immune checkpoint blockade. Recently a novel pan-tumor molecular tissue-based biomarker, the Immunotherapy R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc006b59288a791da1e8eedd00fe6d41
https://doi.org/10.1101/2023.04.11.23288423
https://doi.org/10.1101/2023.04.11.23288423
Autor:
Monika Gulia-Nuss, Andrew B. Nuss, Jason M. Meyer, Daniel E. Sonenshine, R. Michael Roe, Robert M. Waterhouse, David B. Sattelle, José de la Fuente, Jose M. Ribeiro, Karine Megy, Jyothi Thimmapuram, Jason R. Miller, Brian P. Walenz, Sergey Koren, Jessica B. Hostetler, Mathangi Thiagarajan, Vinita S. Joardar, Linda I. Hannick, Shelby Bidwell, Martin P. Hammond, Sarah Young, Qiandong Zeng, Jenica L. Abrudan, Francisca C. Almeida, Nieves Ayllón, Ketaki Bhide, Brooke W. Bissinger, Elena Bonzon-Kulichenko, Steven D. Buckingham, Daniel R. Caffrey, Melissa J. Caimano, Vincent Croset, Timothy Driscoll, Don Gilbert, Joseph J. Gillespie, Gloria I. Giraldo-Calderón, Jeffrey M. Grabowski, David Jiang, Sayed M. S. Khalil, Donghun Kim, Katherine M. Kocan, Juraj Koči, Richard J. Kuhn, Timothy J. Kurtti, Kristin Lees, Emma G. Lang, Ryan C. Kennedy, Hyeogsun Kwon, Rushika Perera, Yumin Qi, Justin D. Radolf, Joyce M. Sakamoto, Alejandro Sánchez-Gracia, Maiara S. Severo, Neal Silverman, Ladislav Šimo, Marta Tojo, Cristian Tornador, Janice P. Van Zee, Jesús Vázquez, Filipe G. Vieira, Margarita Villar, Adam R. Wespiser, Yunlong Yang, Jiwei Zhu, Peter Arensburger, Patricia V. Pietrantonio, Stephen C. Barker, Renfu Shao, Evgeny M. Zdobnov, Frank Hauser, Cornelis J. P. Grimmelikhuijzen, Yoonseong Park, Julio Rozas, Richard Benton, Joao H. F. Pedra, David R. Nelson, Maria F. Unger, Jose M. C. Tubio, Zhijian Tu, Hugh M. Robertson, Martin Shumway, Granger Sutton, Jennifer R. Wortman, Daniel Lawson, Stephen K. Wikel, Vishvanath M. Nene, Claire M. Fraser, Frank H. Collins, Bruce Birren, Karen E. Nelson, Elisabet Caler, Catherine A. Hill
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Ticks transmit a large number of pathogens that cause human diseases. Here, the authors sequence the genome of the tick Ixodes scapularisand uncover expansion of genes associated with parasitic processes unique to ticks and tick-host interactions.
Externí odkaz:
https://doaj.org/article/fa4043b3779c4d0db50b094e385f7e3b
Autor:
Alicia L. Bruzos, Martín Santamarina, Daniel García-Souto, Seila Díaz, Sara Rocha, Jorge Zamora, Yunah Lee, Alejandro Viña-Feás, Michael A. Quail, Iago Otero, Ana Pequeño-Valtierra, Javier Temes, Jorge Rodriguez-Castro, Antonio Villanueva, Damián Costas, Rosana Rodríguez, Tamara Prieto, Laura Tomás, Pilar Alvariño, Juana Alonso, Asunción Cao, David Iglesias, María J. Carballal, Ana M. Amaral, Pablo Balseiro, Ricardo Calado, Bouchra El Khalfi, Urtzi Izagirre, Xavier de Montaudouin, Nicolas G. Pade, Ian Probert, Fernando Ricardo, Pamela Ruiz, Maria Skazina, Katarzyna Smolarz, Juan J. Pasantes, Antonio Villalba, Zemin Ning, Young Seok Ju, David Posada, Jonas Demeulemeester, Adrian Baez-Ortega, Jose M. C. Tubio
Publikováno v:
bioRxiv
Transmissible cancers are malignant cell clones that spread among individuals through transfer of living cancer cells. Several such cancers, collectively known as bivalve transmissible neoplasia (BTN), are known to infect and cause leukaemia in marin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5278688b39a0e982254f8535967698c5
https://doi.org/10.1101/2022.08.06.503021
https://doi.org/10.1101/2022.08.06.503021
Autor:
Alexandra Colquhoun, Andrew Menzies, Andrew R. J. Lawson, Jose M. C. Tubio, Michael R. Stratton, Luiza Moore, Tim H. H. Coorens, Krishnaa T. Mahbubani, Inigo Martincorena, William Turner, Nicholas Williams, Laura O’Neill, Luke M. R. Harvey, Peter J. Campbell, Jyoti Nangalia, Kourosh Saeb-Parsy, Harald Vöhringer, Bethany Bareham, Sonia Zumalave, Calli Latimer, Vincent Gnanapragasam, Benjamin Thomas, Federico Abascal, Alex Cagan, Mathijs A. Sanders, Anne Y. Warren, Tim Butler, Keiran Raine, Doris Rassl, Yvette Hooks, Moritz Gerstung, Thomas J. Mitchell
Publikováno v:
Science, 370(6512), 75-82. American Association for the Advancement of Science
Genetic profiles of the bladder Depending on the environment of the individual, the human bladder can be exposed to carcinogens as they are flushed through the body. Lawson et al. and Li et al. examined the genetic composition of laser-dissected micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e2aeed9063ef470902d2de96a0784f
https://doi.org/10.1126/science.aba8347
https://doi.org/10.1126/science.aba8347
Autor:
Miguel A. Pavón, Sonia Zumalave, Myriam Cuadrado, Antonio Abad, Carmen Segrelles, Xosé R. Bustelo, Gloria Pascual, Natalia Fernández-Parejo, María C. García-Macías, Salvador Aznar Benitah, Rogelio González-Sarmiento, Salvatore Fabbiano, Juan P. Rodrigo, Sonia Rodríguez-Fdez, Nazareno González, Mauricio Menacho-Márquez, L. Francisco Lorenzo-Martín, Javier Robles-Valero, Juana M. García-Pedrero, Pablo Lorenzano-Menna, Jesús M. Paramio, Jose M. C. Tubio
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Dipòsit Digital de la UB
Universidad de Barcelona
Digital.CSIC. Repositorio Institucional del CSIC
Nature Communications
RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Dipòsit Digital de la UB
Universidad de Barcelona
Digital.CSIC. Repositorio Institucional del CSIC
Nature Communications
RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)
© The Author(s) 2020.
Regenerative proliferation capacity and poor differentiation are histological features usually linked to poor prognosis in head and neck squamous cell carcinoma (hnSCC). However, the pathways that regulate them remain ill-
Regenerative proliferation capacity and poor differentiation are histological features usually linked to poor prognosis in head and neck squamous cell carcinoma (hnSCC). However, the pathways that regulate them remain ill-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f9e862d0c51daed5c4d0a59fb3a9f7
https://doaj.org/article/383992e6d52c41ef94a9df8bb7b4e08c
https://doaj.org/article/383992e6d52c41ef94a9df8bb7b4e08c