Zobrazeno 1 - 10
of 278
pro vyhledávání: '"Jose Luis Perez‐Gracia"'
Autor:
Ana Patiño-García, Elizabeth Guruceaga, Maria Pilar Andueza, Marimar Ocón, Jafait Junior Fodop Sokoudjou, Nicolás de Villalonga Zornoza, Gorka Alkorta-Aranburu, Ibon Tamayo Uria, Alfonso Gurpide, Carlos Camps, Eloísa Jantus-Lewintre, Maria Navamuel-Andueza, Miguel F. Sanmamed, Ignacio Melero, Mohamed Elgendy, Juan Pablo Fusco, Javier J. Zulueta, Juan P. de-Torres, Gorka Bastarrika, Luis Seijo, Ruben Pio, Luis M. Montuenga, Mikel Hernáez, Idoia Ochoa, Jose Luis Perez-Gracia
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105048- (2024)
Summary: Background: Tobacco is the main risk factor for developing lung cancer. Yet, while some heavy smokers develop lung cancer at a young age, other heavy smokers never develop it, even at an advanced age, suggesting a remarkable variability in t
Externí odkaz:
https://doaj.org/article/325b5d8d436b42f0be4be23054440e34
Autor:
Hendrik-Tobias Arkenau, Jean-Yves Douillard, Nicolas Penel, Teresa Amaral, Ahmad Awada, Emiliano Calvo, Viktor Gruenwald, Jose Luis Perez-Gracia, Ruth Vera, Martijn P Lolkema, Gyorgy Bodoky, Massimo Di Nicola, Miguel F Sanmamed
Publikováno v:
ESMO Open, Vol 5, Iss 3 (2020)
During the last years, there has been a dramatic increase in the administrative and bureaucratic burden associated with clinical research, which has clearly had an impact on its overall efficiency and on the activity of clinical investigators and res
Externí odkaz:
https://doaj.org/article/c8d312d3e1a44b40a040f3c31e8a35a2
Endoscopical and pathological dissociation in severe colitis induced by immune-checkpoint inhibitors
Autor:
Carlos Eduardo de Andrea, Jose Luis Perez-Gracia, Eduardo Castanon, Mariano Ponz-Sarvise, Jose I. Echeveste, Ignacio Melero, Miguel F. Sanmamed, Maria Esperanza Rodriguez-Ruiz
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Checkpoint inhibitors have improved the survival of patients with advanced tumors and show a manageable toxicity profile. However, auto-immune colitis remains a relevant side effect, and combinations of anti-PD1/PDL1 and anti-CTLA-4 increase its inci
Externí odkaz:
https://doaj.org/article/08bc054ae8b442af9a259734225c3883
Autor:
Javier Rodriguez, Eduardo Castañón, Jose Luis Perez-Gracia, Inmaculada Rodriguez, Antonio Viudez, Carlos Alfaro, Carmen Oñate, Guiomar Perez, Fernando Rotellar, Susana Inogés, Ascensión López-Diaz de Cerio, Leyre Resano, Mariano Ponz-Sarvise, Maria E. Rodriguez-Ruiz, Ana Chopitea, Ruth Vera, Ignacio Melero
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-7 (2018)
Abstract Surgically resectable synchronic and metachronic liver metastases of colon cancer have high risk of relapse in spite of standard-of-care neoadjuvant and adjuvant chemotherapy regimens. Dendritic cell vaccines loaded with autologous tumor lys
Externí odkaz:
https://doaj.org/article/67682af09d884a5e9f413bfb90fe5e93
Autor:
Juan Pablo Fusco, Guillermo Pita, María José Pajares, Maria Pilar Andueza, Ana Patiño‐García, Juan P. de‐Torres, Alfonso Gurpide, Javier Zulueta, Rosario Alonso, Nuria Alvarez, Ruben Pio, Ignacio Melero, Miguel F. Sanmamed, Maria Rodriguez Ruiz, Ignacio Gil‐Bazo, Jose María Lopez‐Picazo, Ciro Casanova, Rebeca Baz Davila, Antonio Agudo, Maria Dolores Lozano, Alvaro Gonzalez, Nuria Sala, Eva Ardanaz, Javier Benitez, Luis Montuenga, Anna Gonzalez‐Neira, Jose Luis Perez‐Gracia
Publikováno v:
Cancer Medicine, Vol 7, Iss 7, Pp 3474-3483 (2018)
Abstract Single nucleotide polymorphisms (SNPs) may modulate individual susceptibility to carcinogens. We designed a genome‐wide association study to characterize individuals presenting extreme phenotypes of high and low risk to develop tobacco‐i
Externí odkaz:
https://doaj.org/article/c3b285810a764be5ae798d81e210d99b
Autor:
Celia Prior, Jose Luis Perez-Gracia, Jesus Garcia-Donas, Cristina Rodriguez-Antona, Elizabeth Guruceaga, Emilio Esteban, Cristina Suarez, Daniel Castellano, Aránzazu González del Alba, Maria Dolores Lozano, Joan Carles, Miguel Angel Climent, Jose Angel Arranz, Enrique Gallardo, Javier Puente, Joaquim Bellmunt, Alfonso Gurpide, Jose Maria Lopez-Picazo, Alvaro Gonzalez Hernandez, Begoña Mellado, Esther Martínez, Fernando Moreno, Albert Font, Alfonso Calvo
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86263 (2014)
To identify tissue microRNAs predictive of sunitinib activity in patients with metastatic renal-cell-carcinoma (MRCC) and to evaluate in vitro their mechanism of action in sunitinib resistance.We screened 673 microRNAs using TaqMan Low-density-Arrays
Externí odkaz:
https://doaj.org/article/93829b422d804bc7841b6e9812135dcd
Autor:
Belen Sadaba, Anabel del Barrio, Miguel Angel Campanero, Jose Ramon Azanza, Almudena Gomez-Guiu, Jose Maria Lopez-Picazo, Salvador Martin Algarra, Francisco Guillén Grimá, Maria Blanco Prieto, Jose Luis Perez-Gracia, Alfonso Gurpide
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89747 (2014)
Palonosetron is a potent second generation 5- hydroxytryptamine-3 selective antagonist which can be administered by either intravenous (IV) or oral routes, but subcutaneous (SC) administration of palonosetron has never been studied, even though it co
Externí odkaz:
https://doaj.org/article/732bd83ce7fe475ebabe0fd50f2fd1e3
Autor:
Carlos Alfaro, Natalia Suárez, Ivan Martínez-Forero, Asís Palazón, Ana Rouzaut, Sarai Solano, Esperanza Feijoo, Alfonso Gúrpide, Elixabet Bolaños, Lorena Erro, Juan Dubrot, Sandra Hervás-Stubbs, Alvaro Gonzalez, Jose Luis Perez-Gracia, Ignacio Melero
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17922 (2011)
BACKGROUND: Interleukin-8 (IL-8, CXCL8) is readily produced by human malignant cells. Dendritic cells (DC) both produce IL-8 and express the IL-8 functional receptors CXCR1 and CXCR2. Most human colon carcinomas produce IL-8. IL-8 importance in malig
Externí odkaz:
https://doaj.org/article/9428cbf661274a5ea5ad563c567ea690
Autor:
Ignacio Melero, Jose Luis Perez-Gracia, Maria Pilar Andueza, Juan I. Pascual, Guillermo Mazzolini, Manglio Rizzo, José M. López-Picazo, Bruno Sangro, María Rodríguez-Ruiz, Cecilia Muñoz-Calleja, Inmaculada Rodriguez, Stefanie Gross, Álvaro Gonzalez, Sara F. Landazuri, Guiomar Perez, Salvador Martín-Algarra, Carmen Oñate, Carlos Alfaro, Omar Carranza-Rua, Miguel F. Sanmamed
Purpose: Interleukin-8 (IL8) is a chemokine produced by malignant cells of multiple cancer types. It exerts various functions in shaping protumoral vascularization and inflammation/immunity. We evaluated sequential levels of serum IL8 in preclinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2b2d610902973ecfb504a1fafc8fae2
https://doi.org/10.1158/1078-0432.c.6523544
https://doi.org/10.1158/1078-0432.c.6523544
Autor:
Ignacio Melero, Jose Luis Perez-Gracia, Maria Pilar Andueza, Juan I. Pascual, Guillermo Mazzolini, Manglio Rizzo, José M. López-Picazo, Bruno Sangro, María Rodríguez-Ruiz, Cecilia Muñoz-Calleja, Inmaculada Rodriguez, Stefanie Gross, Álvaro Gonzalez, Sara F. Landazuri, Guiomar Perez, Salvador Martín-Algarra, Carmen Oñate, Carlos Alfaro, Omar Carranza-Rua, Miguel F. Sanmamed
Supplementary Figure 4. Comparison of IL-8 serum concentrations with the serum concentration of IL-6 and c-reactive protein (CRP) in available samples from 14 melanoma and 19 RCC patients from Figure 2A. (**, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152b43b8fd3f5f4505df374c2480d05b
https://doi.org/10.1158/1078-0432.22457246.v1
https://doi.org/10.1158/1078-0432.22457246.v1