Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jose Luis Olmos-Serrano"'
Autor:
Nadine M. Aziz, Jenny A. Klein, Morgan R. Brady, Jose Luis Olmos-Serrano, Vittorio Gallo, Tarik F. Haydar
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 11, Iss 1, Pp 1-17 (2019)
Abstract Background Down syndrome (DS), caused by the triplication of chromosome 21, results in a constellation of clinical features including changes in intellectual and motor function. Although altered neural development and function have been well
Externí odkaz:
https://doaj.org/article/d4b35132fe2e4d9a88c940a86424aa8a
Autor:
Nadine M. Aziz, Faycal Guedj, Jeroen L. A. Pennings, Jose Luis Olmos-Serrano, Ashley Siegel, Tarik F. Haydar, Diana W. Bianchi
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 6 (2018)
Down syndrome (DS) results from triplication of human chromosome 21. Neuropathological hallmarks of DS include atypical central nervous system development that manifests prenatally and extends throughout life. As a result, individuals with DS exhibit
Externí odkaz:
https://doaj.org/article/4afb9f40e6dd49c0acc6497a27082010
Autor:
Jenny A. Klein, Tarik F. Haydar, Morgan R. Brady, Jose Luis Olmos-Serrano, Nadine M. Aziz, Vittorio Gallo
Publikováno v:
Journal of Neurodevelopmental Disorders
Journal of Neurodevelopmental Disorders, Vol 11, Iss 1, Pp 1-17 (2019)
Journal of Neurodevelopmental Disorders, Vol 11, Iss 1, Pp 1-17 (2019)
BackgroundDown syndrome (DS), caused by the triplication of chromosome 21, results in a constellation of clinical features including changes in intellectual and motor function. Although altered neural development and function have been well described
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42722daf5cce4227a9516da699c32291
http://europepmc.org/articles/PMC6913030
http://europepmc.org/articles/PMC6913030
Autor:
Tarik F. Haydar, Jose Luis Olmos-Serrano, Joseph W. Goodliffe, Nadine M. Aziz, Diana W. Bianchi, Faycal Guedj, Jeroen L. A. Pennings
Publikováno v:
The Journal of Neuroscience. 36:2926-2944
Studies in humans with Down syndrome (DS) show that alterations in fetal brain development are followed by postnatal deficits in neuronal numbers, synaptic plasticity, and cognitive and motor function. This same progression is replicated in several m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0cc4b0a8d4faab5619df8f5ec9afc62
https://doi.org/10.1523/jneurosci.2513-15.2016
https://doi.org/10.1523/jneurosci.2513-15.2016
Autor:
Diana W. Bianchi, Ashley E Siegel, Nadine M. Aziz, Faycal Guedj, Jeroen L. A. Pennings, Jose Luis Olmos-Serrano, Tarik F. Haydar
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 11, Iss 6 (2018)
Disease Models & Mechanisms, Vol 11, Iss 6 (2018)
Down syndrome (DS) results from triplication of human chromosome 21. Neuropathological hallmarks of DS include atypical central nervous system development that manifests prenatally and extends throughout life. As a result, individuals with DS exhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3f7c8b62425929fde8951b6ec605418
http://europepmc.org/articles/PMC6031353
http://europepmc.org/articles/PMC6031353
Autor:
Rebecca L. Vislay, Molly M. Huntsman, Sebila Kratovac, Joshua G. Corbin, David L. Nelson, Jose Luis Olmos-Serrano, Brandon S. Martin
Publikováno v:
The Journal of Neuroscience. 33:7548-7558
Fragile X syndrome (FXS) is a debilitating neurodevelopmental disorder thought to arise from disrupted synaptic communication in several key brain regions, including the amygdala, a central processing center for information with emotional and social
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f5b8e1474354ae8e292d6cce5683b0
https://doi.org/10.1523/jneurosci.2764-12.2013
https://doi.org/10.1523/jneurosci.2764-12.2013
Publikováno v:
Developmental Neuroscience. 33:395-403
Hyperactivity, hypersensitivity to auditory stimuli, and exaggerated fear are common behavioral abnormalities observed in individuals with fragile X syndrome (FXS), a neurodevelopmental disorder that is the most common genetic cause of autism. Eviden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::782501670550fd530adee81add841b04
https://doi.org/10.1159/000332884
https://doi.org/10.1159/000332884
Publikováno v:
Developmental Neuroscience. 33:365-378
Fear is a universal response to a threat to one’s body or social status. Disruption in the detection and response of the brain’s fear system is commonly observed in a variety of neurodevelopmental disorders, including fragile X syndrome (FXS), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6633ac802a870386752f8d6c972f684e
https://doi.org/10.1159/000329424
https://doi.org/10.1159/000329424
Autor:
Jose Luis Olmos-Serrano, Scott M. Paluszkiewicz, Joshua G. Corbin, Molly M. Huntsman, Brandon S. Martin, Walter E. Kaufmann
Publikováno v:
Journal of Neuroscience. 30:9929-9938
Fragile X Syndrome (FXS) is a neurodevelopmental disorder characterized by variable cognitive impairment and behavioural disturbances such as exaggerated fear, anxiety and gaze avoidance. Consistent with this, findings from human brain imaging studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::786687a42765817c258b880d0f2dac02
https://doi.org/10.1523/jneurosci.1714-10.2010
https://doi.org/10.1523/jneurosci.1714-10.2010
Autor:
Alan Peters, Claire Sethares, Feng Cheng, William A. Tyler, John Silbereis, Zygmunt Galdzicki, Hyo Jung Kang, Joseph W. Goodliffe, Nathan P. Cramer, Tarik F. Haydar, Jeffrey A. Golden, Ying Zhu, Nenad Sestan, Ivana Delalle, Jose Luis Olmos-Serrano, Mihovil Pletikos, Lucija Jankovic-Rapan
Publikováno v:
Neuron. 89(6)
Trisomy 21, or Down syndrome (DS), is the most common genetic cause of developmental delay and intellectual disability. To gain insight into the underlying molecular and cellular pathogenesis, we conducted a multi-region transcriptome analysis of DS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469813841ca6e4eb3a4bfdf117fcd73f
https://pubmed.ncbi.nlm.nih.gov/26924435
https://pubmed.ncbi.nlm.nih.gov/26924435