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pro vyhledávání: '"Jose Luis Martos"'
Publikováno v:
Tetrahedron Letters. 40:1575-1578
Ethyl 4,4-dimethylpyroglutamate has been used as a chiral auxiliary for α,β-unsaturated acids in Michael addition reactions. The conjugate addition of Grignard reagents to the amides in the presence of copper iodide, tetramethylene diamine (TMEDA)
Publikováno v:
ChemInform. 30
A reduction of the tetracyclic skeleton of sordarins and sordaricins to a cyclopentane ring bearing the pharmacophore functional groups led to new derivatives retaining part of their in vitro and whole-cell activity.
Publikováno v:
ChemInform. 30
Ethyl 4,4-dimethylpyroglutamate has been used as a chiral auxiliary for α,β-unsaturated acids in Michael addition reactions. The conjugate addition of Grignard reagents to the amides in the presence of copper iodide, tetramethylene diamine (TMEDA)
Publikováno v:
CEU Repositorio Institucional
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En: Bioorganic and Medicinal Chemistry Letters. ISSN 0960-894x. n. 9, 1999, págs 103-108 A reduction of the tetracyclic skeleton of sordarins and sordaricins to a cyclopentane ring bearing the pharmacophore functional groups led to new derivatives r