Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jose Luis Lavandera"'
Autor:
Maria G. Gomez-Lorenzo, Ane Rodríguez-Alejandre, Sonia Moliner-Cubel, María Martínez-Hoyos, Noemí Bahamontes-Rosa, Rubén Gonzalez del Rio, Carolina Ródenas, Jesús de la Fuente, Jose Luis Lavandera, Jose F. García-Bustos, Alfonso Mendoza-Losana
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 8, Iss 2, Pp 295-303 (2018)
Phenotypic screening has produced most of the new chemical entities currently in clinical development for malaria, plus many lead compounds active against Plasmodium falciparum asexual stages. However, lack of knowledge about the mode of action of th
Externí odkaz:
https://doaj.org/article/d31fe5e392d8459fb92b14da48cc417a
Autor:
María Martínez-Hoyos, Esther Perez-Herran, Gulcin Gulten, Lourdes Encinas, Daniel Álvarez-Gómez, Emilio Alvarez, Santiago Ferrer-Bazaga, Adolfo García-Pérez, Fátima Ortega, Iñigo Angulo-Barturen, Joaquin Rullas-Trincado, Delia Blanco Ruano, Pedro Torres, Pablo Castañeda, Sophie Huss, Raquel Fernández Menéndez, Silvia González del Valle, Lluis Ballell, David Barros, Sundip Modha, Neeraj Dhar, François Signorino-Gelo, John D. McKinney, Jose Francisco García-Bustos, Jose Luis Lavandera, James C. Sacchettini, M. Soledad Jimenez, Nuria Martín-Casabona, Julia Castro-Pichel, Alfonso Mendoza-Losana
Publikováno v:
EBioMedicine, Vol 8, Iss C, Pp 291-301 (2016)
Despite being one of the first antitubercular agents identified, isoniazid (INH) is still the most prescribed drug for prophylaxis and tuberculosis (TB) treatment and, together with rifampicin, the pillars of current chemotherapy. A high percentage o
Externí odkaz:
https://doaj.org/article/24f2b3c2204144699909714a57e27a13
Autor:
Erika Meléndez-Oliva, Isabel Sánchez-Vera Gómez-Trelles, Eva Segura-Orti, Borja Pérez-Domínguez, Rafael García-Maset, Alicia García-Testal, Jose Luis Lavandera-Díaz
Publikováno v:
International urology and nephrology. 54(9)
Chronic kidney disease patients on hemodialysis treatment are characterized by increased levels of inflammatory markers and oxidative stress, in addition to a significant deterioration in physical function. The benefits of physical exercise on the fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d427128d5de447aba4a0b6a30d79792
https://pubmed.ncbi.nlm.nih.gov/35199237
https://pubmed.ncbi.nlm.nih.gov/35199237
Autor:
Sonia Moliner-Cubel, Jesús Ángel de la Fuente, Maria G. Gomez-Lorenzo, Noemí Bahamontes-Rosa, Jose Luis Lavandera, Ruben Gonzalez Del Rio, María Martínez-Hoyos, Alfonso Mendoza-Losana, Carolina Ródenas, Jose F. Garcia-Bustos, Ane Rodríguez-Alejandre
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 8, Iss 2, Pp 295-303 (2018)
International Journal for Parasitology: Drugs and Drug Resistance
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
International Journal for Parasitology: Drugs and Drug Resistance
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Phenotypic screening has produced most of the new chemical entities currently in clinical development for malaria, plus many lead compounds active against Plasmodium falciparum asexual stages. However, lack of knowledge about the mode of action of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fa76b73e95e10266a10422f53f7a89
http://www.sciencedirect.com/science/article/pii/S2211320717301203
http://www.sciencedirect.com/science/article/pii/S2211320717301203
Autor:
Alfonso Mendoza, Cindy Richards, Modesto J. Remuiñán, Joaquín Rullas, Iñigo Angulo-Barturen, Delia Blanco, Ermias Woldu, Julia Castro, Esther Pérez-Herrán, Ruben Gonzalez Del Rio, Monica Cacho, María Jesús Vázquez-Muñiz, David Barros, Jose Luis Lavandera, Lluis Ballell, María Cleofé Zapatero-González
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:1868-1875
One way to speed up the TB drug discovery process is to search for antitubercular activity among compound series that already possess some of the key properties needed in anti-infective drug discovery, such as whole-cell activity and oral absorption.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba2bf7f6f3c37f4a5c61e948231996d
https://doi.org/10.1128/aac.03913-14
https://doi.org/10.1128/aac.03913-14
Autor:
Pilar Manzano, Jose Luis Lavandera, Esther Porras, Francisco-Javier Gamo, Simon J. F. Macdonald, Jose M. Bueno, María Luisa León, Esther Fernández, Félix Calderón, David Barros, Julia Castro, Jose M. Coteron, Jose M. Fiandor, Araceli Mallo
Publikováno v:
ACS Medicinal Chemistry Letters. 2:741-746
In 2010, GlaxoSmithKline published the structures of 13533 chemical starting points for antimalarial lead identification. By using an agglomerative structural clustering technique followed by computational filters such as antimalarial activity, physi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d1fb0a862a7784e6a1cb843e968536
https://doi.org/10.1021/ml200135p
https://doi.org/10.1021/ml200135p
Autor:
Jose Luis Lavandera, Juan E. Puche, Mariano García-Magariño, Inma Castilla-Cortázar, Victor Javier Lara, Úrsula Muñoz
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d6e88990f17f8d89f59724a59b09beb
https://doi.org/10.1530/endoabs.35.p668
https://doi.org/10.1530/endoabs.35.p668
Autor:
Lúcia Dias da Silva Guerra, Inma Castilla-Cortázar, Jose Luis Lavandera, Juan E. Puche, Rima Barhoum, E. Escudero, Úrsula Muñoz
Publikováno v:
Journal of physiology and biochemistry. 70(1)
Insulin-like growth factor-1 (IGF-1) is responsible for many systemic growth hormone (GH) functions although it has an extensive number of inherent activities (anabolic, cytoprotective, and anti-inflammatory). The potential options for IGF-1 therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0781926a4cfda08a4d7f32d0778e2d01
https://pubmed.ncbi.nlm.nih.gov/24043429
https://pubmed.ncbi.nlm.nih.gov/24043429
Publikováno v:
Biomedical microdevices. 13(6)
The aim was to study the ability of bioadhesive cyclodextrin-poly(anhydride) nanoparticles as carriers for the oral delivery of atovaquone (ATO). In order to increase the loading capacity of ATO by poly(anhydride) nanoparticles, the following oligosa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e0c26ccc6530dbf9807b82385c5312
https://pubmed.ncbi.nlm.nih.gov/21773725
https://pubmed.ncbi.nlm.nih.gov/21773725
Autor:
Santiago Ferrer, María T. Fraile, Jose M. Bueno, Jesús Chicharro, Domingo Gargallo-Viola, Esperanza Herreros, María C. García, Rubén M. Gómez, Jose Luis Lavandera, J. Vidal, Margarita Puente, Jose M. Fiandor, Adolfo García, Pilar Manzano, Milagros Lorenzo
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(18)
Antimalarial 4-pyridones are a novel class of inhibitors of the plasmodial mitochondrial electron transport chain targeting Cytochrome bc1 (complex III). In general, the most potent 4-pyridones are lipophilic molecules with poor solubility in aqueous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a2e2bb1ca5b3c1c30877e5a4f5588c1
https://pubmed.ncbi.nlm.nih.gov/21824778
https://pubmed.ncbi.nlm.nih.gov/21824778