Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Jose Luis Abad"'
1
Akademický článek
Jaspine B induces nonapoptotic cell death in gastric cancer cells independently of its inhibition of ceramide synthase
Autor: Francesca Cingolani, Fabio Simbari, Jose Luis Abad, Mireia Casasampere, Gemma Fabrias, Anthony H. Futerman, Josefina Casas
Publikováno v: Journal of Lipid Research, Vol 58, Iss 8, Pp 1500-1513 (2017)
Sphingolipids (SLs) have been extensively investigated in biomedical research due to their role as bioactive molecules in cells. Here, we describe the effect of a SL analog, jaspine B (JB), a cyclic anhydrophytosphingosine found in marine sponges, on
Externí odkaz: https://doaj.org/article/941fee4dc31a45058d91b6e7b3dc22ce
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2
Akademický článek
Biodistribution and Efficacy of Human Adipose-Derived Mesenchymal Stem Cells Following Intranodal Administration in Experimental Colitis
Autor: Mercedes Lopez-Santalla, Pablo Mancheño-Corvo, Amelia Escolano, Ramon Menta, Olga DelaRosa, Jose Luis Abad, Dirk Büscher, Juan M. Redondo, Juan A. Bueren, Wilfried Dalemans, Eleuterio Lombardo, Marina I. Garin
Publikováno v: Frontiers in Immunology, Vol 8 (2017)
Mesenchymal stem cells (MSCs) have a large potential in cell therapy for treatment of inflammatory and autoimmune diseases, thanks to their immunomodulatory properties. The encouraging results in animal models have initiated the translation of MSC th
Externí odkaz: https://doaj.org/article/458d1a85c4474d0db9e33f3c1b9c1833
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5
Akademický článek
Uretero-iliac artery fistula: an uncommon life-threatening cause of hematuria. A case report
Autor: Silvia Alvarez-Bandrés, José Luis Abades-Vázquez, Iosu Aldekoa-Hurtado, Santiago Ezquerro-Sáenz
Publikováno v: Revista Información Científica, Vol 103, Iss 0, Pp e4772-e4772 (2024)
Uretero-arterial fistula (UAF) is an uncommon but potentially life-threatening condition that usually manifests as hematuria. We report a new case of UAF presenting with massive bleeding and hypovolemic shock in a patient with a history of vascular p
Externí odkaz: https://doaj.org/article/c83af868be4941ed9935c9dd9734fda9
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6
Methuosis Contributes to Jaspine-B-Induced Cell Death
Autor: Núria Bielsa, Mireia Casasampere, Jose Luis Abad, Carlos Enrich, Antonio Delgado, Gemma Fabriàs, Jose M. Lizcano, Josefina Casas
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 7257
Methuosis is a type of programmed cell death in which the cytoplasm is occupied by fluid-filled vacuoles that originate from macropinosomes (cytoplasmic vacuolation). A few molecules have been reported to behave as methuosis inducers in cancer cell l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9106da2f20b43c8d0314df44565ad10c
http://hdl.handle.net/10261/275227
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7
Akademický článek
High-throughput discovery of novel small-molecule inhibitors of acid Ceramidase
Autor: Mazen Aseeri, José Luis Abad, Antonio Delgado, Gemma Fabriàs, Gemma Triola, Josefina Casas
Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1, Pp 343-348 (2023)
Ceramide has a key role in the regulation of cellular senescence and apoptosis. As Ceramide levels are lowered by the action of acid ceramidase (AC), abnormally expressed in various cancers, the identification of AC inhibitors has attracted increasin
Externí odkaz: https://doaj.org/article/156873fa613f4a8494cfb3580d846fcf
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8
SCOTfluors: Small, Conjugatable, Orthogonal, and Tunable Fluorophores for In Vivo Imaging of Cell Metabolism
Autor: Sam Benson, Antonio Fernandez, Nicole D. Barth, Fabio de Moliner, Mathew H. Horrocks, C. Simon Herrington, Jose Luis Abad, Antonio Delgado, Lisa Kelly, Ziyuan Chang, Yi Feng, Miyako Nishiura, Yuichiro Hori, Kazuya Kikuchi, Marc Vendrell
Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Angewandte Chemie (International Ed. in English)
Benson, S, Fernandez, A, Barth, N D, De Moliner, F, Horrocks, M H, Herrington, C S, Abad, J L, Delgado, A, Kelly, L, Chang, Z, Feng, Y, Nishiura, M, Hori, Y, Kikuchi, K & Vendrell, M 2019, ' SCOTfluors: Small, Conjugatable, Orthogonal and Tunable Fluorophores for in vivo Imaging of Cell Metabolism ', Angewandte Chemie, vol. 131, no. 21, pp. 6985-6989 . https://doi.org/10.1002/ange.201900465
Digital.CSIC. Repositorio Institucional del CSIC
instname
The transport and trafficking of metabolites are critical for the correct functioning of live cells. However, in situ metabolic imaging studies are hampered by the lack of fluorescent chemical structures that allow direct monitoring of small metaboli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f34ad2d0e518254aa03f1c0695308169
http://hdl.handle.net/2445/171908
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10
Akademický článek
A fluorogenic substrate for the detection of lipid amidases in intact cells
Autor: Mireia Casasampere, Johnson Ung, Alejandro Iñáñez, Carine Dufau, Kazuhito Tsuboi, Josefina Casas, Su-Fern Tan, David J. Feith, Nathalie Andrieu-Abadie, Bruno Segui, Thomas P. Loughran, Jr., José Luis Abad, Gemma Fabrias
Publikováno v: Journal of Lipid Research, Vol 65, Iss 3, Pp 100520- (2024)
Lipid amidases of therapeutic relevance include acid ceramidase (AC), N-acylethanolamine-hydrolyzing acid amidase, and fatty acid amide hydrolase (FAAH). Although fluorogenic substrates have been developed for the three enzymes and high-throughput me
Externí odkaz: https://doaj.org/article/cbc54b7eb8e74f508add3ca8fe1b0079
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