Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jose Luis, Millan"'
Autor:
Saida Mebarek, Rene Buchet, Slawomir Pikula, Agnieszka Strzelecka-Kiliszek, Leyre Brizuela, Giada Corti, Federica Collacchi, Genevieve Anghieri, Andrea Magrini, Pietro Ciancaglini, Jose Luis Millan, Owen Davies, Massimo Bottini
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 42 (2023)
Mineralization-competent cells, including hypertrophic chondrocytes, mature osteoblasts, and osteogenic-differentiated smooth muscle cells secrete media extracellular vesicles (media vesicles) and extracellular vesicles bound to the extracellular mat
Externí odkaz:
https://doaj.org/article/198c8fda4c7242e4a692415ec39e0a01
Autor:
Flavia Amadeu de Oliveira, Fatma F. Mohamed, Yuka Kinoshita, Sonoko Narisawa, Colin Farquharson, Koichi Miyake, Brian L Foster, Jose Luis Millan
Publikováno v:
JBMR Plus, Vol 7, Iss 1, Pp n/a-n/a (2023)
ABSTRACT Hypophosphatasia (HPP), caused by loss‐of‐function mutations in the ALPL gene encoding tissue‐nonspecific alkaline phosphatase (TNAP), is characterized by skeletal and dental hypomineralization that can vary in severity from life‐thr
Externí odkaz:
https://doaj.org/article/513ba8e0b1914747a10e53df0d3557f7
Autor:
Dean A. Houston, Louise A. Stephen, Soher N. Jayash, Katherine Myers, Kirsty Little, Mark Hopkinson, Andrew A. Pitsillides, Vicky E. MacRae, Jose Luis Millan, Katherine A. Staines, Colin Farquharson
Publikováno v:
Cell Biochemistry and Function. 41:189-201
The administration of intermittent parathyroid hormone (iPTH) is anabolic to the skeleton. Recent studies with cultured osteoblasts have revealed that the expression of PHOSPHO1, a bone-specific phosphatase essential for the initiation of mineralisat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9980129c74d7ff8406be9f785e25fbb7
https://doi.org/10.1002/cbf.3772
https://doi.org/10.1002/cbf.3772
Autor:
Roman N. Rodionov, Hoshimjon Begmatov, Natalia Jarzebska, Ketul Patel, Matthew T. Mills, Zulaikha Ghani, Doreen Khakshour, Pankti Tamboli, Mitul N. Patel, Mirette Abdalla, Maryann Assaf, Stefan R. Bornstein, Jose Luis Millan, Stefanie M. Bode‐Böger, Jens Martens‐Lobenhoffer, Norbert Weiss, Olga V. Savinova
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 14 (2019)
Background Homoarginine (hArg) has been shown to be cardioprotective in a model of ischemic heart failure; however, the mechanism remains unknown. hArg can inhibit tissue‐nonspecific alkaline phosphatase (TNAP), an enzyme that promotes vascular cal
Externí odkaz:
https://doaj.org/article/5033680c581c467088aa6196a5ea9213
Autor:
Jordan Tzvetkov, Louise A. Stephen, Scott Dillon, Jose Luis Millan, Anke J. Roelofs, Cosimo De Bari, Colin Farquharson, Tony Larson, Paul Genever
Funder: Biotechnology and Biological Sciences Research Council; Id: http://dx.doi.org/10.13039/501100000268
Funder: Versus Arthritis; Id: http://dx.doi.org/10.13039/501100012041
Lipids play a crucial role in signaling and metabolism, regula
Funder: Versus Arthritis; Id: http://dx.doi.org/10.13039/501100012041
Lipids play a crucial role in signaling and metabolism, regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e77c804a784d713f2da712d1f547adc
https://www.repository.cam.ac.uk/handle/1810/347571
https://www.repository.cam.ac.uk/handle/1810/347571
Autor:
Flavia Amadeu de Oliveira, Fatma F. Mohamed, Yuka Kinoshita, Sonoko Narisawa, Colin Farquharson, Koichi Miyake, Brian L Foster, Jose Luis Millan
Publikováno v:
Amadeu De Oliveira, F, Mohamed, F F, Kinoshita, Y, Narisawa, S, Farquharson, C, Miyake, K, Foster, B L & Millán, J L 2022, ' Gene therapy using recombinant AAV type 8 vector encoding TNAP-D10 improves the skeletal phenotypes in murine models of osteomalacia ', JBMR Plus, vol. 7, no. 1, e10709, pp. 1-16 . https://doi.org/10.1002/jbm4.10709
Hypophosphatasia (HPP), caused by loss-of-function mutations in the ALPL gene encoding tissue-nonspecific alkaline phosphatase (TNAP), is characterized by skeletal and dental hypomineralization that can vary in severity from life-threatening to milde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c5b95f9b7f3625e0eba945f7bb67495
https://www.pure.ed.ac.uk/ws/files/314821450/JBMR_Plus_2022_Amadeu_de_Oliveira_Gene_Therapy_Using_Recombinant_AAV_Type_8_Vector_Encoding_TNAP_D10_Improves_the_1_.pdf
https://www.pure.ed.ac.uk/ws/files/314821450/JBMR_Plus_2022_Amadeu_de_Oliveira_Gene_Therapy_Using_Recombinant_AAV_Type_8_Vector_Encoding_TNAP_D10_Improves_the_1_.pdf
Autor:
Laurence Bessueille, Lynn Kawtharany, Thibaut Quillard, Claudia Goettsch, Anne Briolay, Nirina Taraconat, Stéphane Balayssac, Véronique Gilard, Saida Mebarek, Olivier Peyruchaud, François Duboeuf, Caroline Bouillot, Anthony Pinkerton, Laura Mechtouff, René Buchet, Eva Hamade, Kazem Zibara, Caroline Fonta, Emmanuelle Canet-soulas, Jose luis Millan, David Magne
Publikováno v:
Translational Research, The Journal of Laboratory and Clinical Medicine
Translational Research, The Journal of Laboratory and Clinical Medicine, 2022, ⟨10.1016/j.trsl.2022.06.010⟩
Translational Research, The Journal of Laboratory and Clinical Medicine, 2022, ⟨10.1016/j.trsl.2022.06.010⟩
International audience; Calcium accumulation in atherosclerotic plaques predicts cardiovascular mortality, but the mechanisms responsible for plaque calcification and how calcification impacts plaque stability remain debated. Tissue-nonspecific alkal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328440433cca054dc0b1d8f70e783bf8
https://hal.science/hal-03718207
https://hal.science/hal-03718207
Autor:
Bo Yang, Mingliang Qu, Rengang Wang, Jon E Chatterton, Xiao-Bo Liu, Bing Zhu, Sonoko Narisawa, Jose Luis Millan, Nobuki Nakanishi, Kathryn Swoboda, Stuart A Lipton, Dongxian Zhang
Publikováno v:
eLife, Vol 4 (2015)
Hitherto, membralin has been a protein of unknown function. Here, we show that membralin mutant mice manifest a severe and early-onset motor neuron disease in an autosomal recessive manner, dying by postnatal day 5–6. Selective death of lower motor
Externí odkaz:
https://doaj.org/article/6372ba534f6042f3a37c0d0883d048b4
Autor:
Claudia, Goettsch, Agnieszka, Strzelecka-Kiliszek, Laurence, Bessueille, Thibaut, Quillard, Laura, Mechtouff, Slawomir, Pikula, Emmanuelle, Canet-Soulas, Jose Luis, Millan, Caroline, Fonta, David, Magne
Publikováno v:
Cardiovascular Research
Cardiovascular Research, Oxford University Press (OUP), 2020, pp.cvaa299. ⟨10.1093/cvr/cvaa299⟩
Cardiovascular Research, 2022, 118 (1), pp.84-96. ⟨10.1093/cvr/cvaa299⟩
Cardiovascular Research, Oxford University Press (OUP), 2020, ⟨10.1093/cvr/cvaa299⟩
Cardiovascular Research, Oxford University Press (OUP), 2020, pp.cvaa299. ⟨10.1093/cvr/cvaa299⟩
Cardiovascular Research, 2022, 118 (1), pp.84-96. ⟨10.1093/cvr/cvaa299⟩
Cardiovascular Research, Oxford University Press (OUP), 2020, ⟨10.1093/cvr/cvaa299⟩
Cardiovascular calcification (CVC) is associated with increased morbidity and mortality. It develops in several diseases and locations, such as in the tunica intima in atherosclerosis plaques, in the tunica media in type 2 diabetes and chronic kidney
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c26bf50ef3aaffafe475c13e107673f2
https://www.hal.inserm.fr/inserm-03261168
https://www.hal.inserm.fr/inserm-03261168
Autor:
Anton Mararenko, Ralph Bar-El, Maryann Assaf, Pranav Singla, Ian Kelly, Dorinamaria Carka, Jose Luis Millan, Brian L Beatty, Olga V Savinova
Publikováno v:
Circulation. 138
Background: Atherosclerosis is an inflammatory disease that contributes significantly to cardiovascular mortality. Arterial stiffening due to calcification can coexist with or directly influence pathogenesis of atherosclerosis. We hypothesize that ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc00dfe10a3cd681d340188e44c449b1
https://doi.org/10.1161/circ.138.suppl_1.17183
https://doi.org/10.1161/circ.138.suppl_1.17183