Human Oral Epithelial Cells Suppress T Cell Function via Prostaglandin E2 Secretion

Autor: Jose L. Sanchez-Trincado, Hector F. Pelaez-Prestel, Esther M. Lafuente, Pedro A. Reche

Publikováno v: Frontiers in Immunology, Vol 12 (2022)

The oral mucosa is constantly exposed to a plethora of stimuli including food antigens, commensal microbiota and pathogens, requiring distinct immune responses. We previously reported that human oral epithelial cells (OECs) suppress immune responses

Externí odkaz: https://doaj.org/article/02933fec5cf64b8c80f14bc5dd2a1b66

Fundamentals and Methods for T- and B-Cell Epitope Prediction

Autor: Jose L. Sanchez-Trincado, Marta Gomez-Perosanz, Pedro A. Reche

Publikováno v: Journal of Immunology Research, Vol 2017 (2017)

Adaptive immunity is mediated by T- and B-cells, which are immune cells capable of developing pathogen-specific memory that confers immunological protection. Memory and effector functions of B- and T-cells are predicated on the recognition through sp

Externí odkaz: https://doaj.org/article/a48f58f35d2248e5a67a26e267ddfbc8

Generation of Variability-Free Reference Proteomes from Pathogenic Organisms for Epitope-Vaccine Design

Autor: Jose L, Sanchez-Trincado, Pedro A, Reche

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2131

Many pathogenic organisms have an inherent ability to rapidly evolve into new variants, which enables them to escape previously existing immune responses. Vaccine design strategies should be aimed to counteract such variability, targeting the conserv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5491a1fb0975872712dc66ba9b6d0ec1
https://pubmed.ncbi.nlm.nih.gov/32162259

RIAM-VASP Module Relays Integrin Complement Receptors in Outside-In Signaling Driving Particle Engulfment

Autor: Jose L. Sanchez-Trincado, Raúl Torres-Ruiz, Esther M. Lafuente, María Yáñez-Mó, Sandra Rodriguez-Perales, Carlos Cabañas, Pedro A. Reche, Víctor Toribio, Alvaro Torres-Gomez

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Repisalud
Instituto de Salud Carlos III (ISCIII)
Cells, Vol 9, Iss 1166, p 1166 (2020)
E-Prints Complutense: Archivo Institucional de la UCM
Universidad Complutense de Madrid
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid
Cells
Volume 9
Issue 5
Digital.CSIC. Repositorio Institucional del CSIC
instname
E-Prints Complutense. Archivo Institucional de la UCM
Recercat. Dipósit de la Recerca de Catalunya
Biblos-e Archivo. Repositorio Institucional de la UAM

The phagocytic integrins and complement receptors &alpha
M&beta
2/CR3 and &alpha
X&beta
2/CR4 are classically associated with the phagocytosis of iC3b-opsonized particles. The activation of this receptor is dependent on signals de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0774b6177815f64488393eda5718d62
https://ddd.uab.cat/record/236425

Naturally presented HLA class I–restricted epitopes from the neurotrophic factor S100-β are targets of the autoimmune response in type 1 diabetes

Autor: Aurelio M Sueiro, Jose L. Sanchez-Trincado, Cristina Calviño-Sampedro, Rubén Varela Calviño, Juan E. Viñuela, Pedro A. Reche, Miguel A. Rodríguez, Marta Gomez-Perosanz, Iria Gomez-Tourino, Oscar J. Cordero

Publikováno v: Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
The FASEB Journal

Type 1 diabetes (T1D) results from the destruction of pancreatic β-cells by the immune system, and CD8+ T lymphocytes are critical actors in this autoimmune response. Pancreatic islets are surrounded by a mesh of nervous cells, the peri-insular Schw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ed0411a14c56182b97079c888ec77e
https://hdl.handle.net/10347/18515