Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jose L. Padilla-Torres"'
Autor:
Megan J. Smithey, Janko Nikolich-Žugich, Sarah A. Foster, Jennifer L. Uhrlaub, Janka Petravic, Kei Nakachi, Jason L. Pugh, Alona S. Sukhina, Jose L. Padilla-Torres, Tomonori Hayashi
Publikováno v:
Aging Cell
Summary Aging‐related decline in immunity is believed to be the main driver behind decreased vaccine efficacy and reduced resistance to infections in older adults. Unrepaired DNA damage is known to precipitate cellular senescence, which was hypothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84465e0668fbd8a80387077b6562223f
Autor:
David G. Besselsen, Eugene W. Gerner, Ignacio Moreno de Alboránç, Jose M. Guillen-R, Raymond B. Nagle, Hana Holubec, Jose L. Padilla-Torres, Natalia A. Ignatenko, Karen A. Blohm-Mangone
Publikováno v:
Cancer Biology & Therapy. 5:1658-1664
The c-MYC oncogene plays an important role in tumorigenesis and is commonly highly expressed in gastrointestinal cancers. In colon cells, c-MYC is regulated by the adenomatous polyposis coli (Apc) tumor suppressor gene. Multiple intestinal neoplasia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07bac86c9b79b17634d69827c269edd0
https://doi.org/10.4161/cbt.5.12.3376
https://doi.org/10.4161/cbt.5.12.3376
Autor:
Jose M. Guillen-R, Jose L. Padilla-Torres, Eugene W. Gerner, David E. Stringer, Natalia A. Ignatenko, Karen A. Blohm-Mangone, Upal K. Basu Roy, David G. Besselsen
Publikováno v:
Nutrition and Cancer. 56:172-181
The nonsteroidal antiinflammatory drug sulindac displays chemopreventive activity in patients with familial adenomatous polyposis (FAP). Sulindac metabolites induce apoptosis in colon tumor cells, in part, by a polyamine-dependent mechanism that can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a9590851df6dee3810c0ac129e4919
https://doi.org/10.1207/s15327914nc5602_8
https://doi.org/10.1207/s15327914nc5602_8
Autor:
Hana Holubec, Natalia A. Ignatenko, Karen A. Blohm-Mangone, David G. Besselsen, Lois Ramsey, Harris Bernstein, Monique Dall'Agnol, Harinder S. Garewal, Claire M. Payne, Katerina Dvorak, Jose L. Padilla-Torres, Eugene W. Gerner, Haiyan Cui, Carol Bernstein
Publikováno v:
Inflammatory Bowel Diseases. 12:278-293
Background: A high-fat diet is a risk factor for the development of inflammatory bowel disease (IBD) in humans. Deoxycholate (DOC) is increased in the colonic contents in response to a high-fat diet. Thus, an elevated level of DOC in the colonic lume
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ac98c61c86d30c08152788c7e4a3ae
https://doi.org/10.1097/01.mib.0000209789.14114.63
https://doi.org/10.1097/01.mib.0000209789.14114.63
Autor:
Natalia A, Ignatenko, Hana, Holubec, David G, Besselsen, Karen A, Blohm-Mangone, Jose L, Padilla-Torres, Raymond B, Nagle, Ignacio Moreno, de Alboránç, Jose M, Guillen-R, Eugene W, Gerner
Publikováno v:
Cancer biologytherapy. 5(12)
The c-MYC oncogene plays an important role in tumorigenesis and is commonly highly expressed in gastrointestinal cancers. In colon cells, c-MYC is regulated by the adenomatous polyposis coli (Apc) tumor suppressor gene. Multiple intestinal neoplasia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95c8ccc222e3a79dbbee9d5aad96fc9c
https://pubmed.ncbi.nlm.nih.gov/17106247
https://pubmed.ncbi.nlm.nih.gov/17106247
Autor:
Eugene W. Gerner, Katerina Dvorak, Claire M. Payne, Harris Bernstein, Hana Holubec, Jose L. Padilla-Torres, David G. Besselsen, Natalia A. Ignatenko, Karen A. Blohm-Mangone, Carol Bernstein, Barbora Dvorakova, Harinder S. Garewal
Publikováno v:
Digestive diseases and sciences. 52(3)
Nos2 knockout mice were compared to wild-type mice for susceptibility to colitis in response to a diet supplemented with deoxycholate, a bile acid increased in the colon of individuals on a high-fat diet. Wild-type mice fed a fat-related diet, supple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a068bbe34f3dbc5479d969b1853947fb
https://pubmed.ncbi.nlm.nih.gov/17253130
https://pubmed.ncbi.nlm.nih.gov/17253130
Autor:
David E. Stringer, Jose Guillen, Natalia A. Ignatenko, Karen A. Blohm-Mangone, Jose L. Padilla-Torres, Hagit F. Yerushalmi, Claire M. Payne, Eugene W. Gerner, Hana Holubec, David G. Besselsen
Publikováno v:
Molecular carcinogenesis. 45(10)
We evaluated the role of polyamines in arginine-dependent intestinal tumorigenesis in ApcMin/+ mice. Arginine is a substrate for ornithine synthesis and thus can influence polyamine production. Supplementing the diet with arginine increased intestina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::885753ba85039f10ba725bf0c8f95079
https://pubmed.ncbi.nlm.nih.gov/16705737
https://pubmed.ncbi.nlm.nih.gov/16705737
Autor:
Claire M. Payne, Natalia A. Ignatenko, Karen A. Blohm-Mangone, David E. Stringer, Jose L. Padilla-Torres, Eugene W. Gerner, Haiyan Cui, Hagit F. Yerushalmi, Hana Holubec, David G. Besselsen
Publikováno v:
Molecular carcinogenesis. 45(2)
Arginine is catabolized by NOS2 and other nitric oxide synthases to form nitric oxide. We evaluated the roles of dietary arginine and Nos2 in Apc-dependent intestinal tumorigenesis in Min mice with and without a functional Nos2 gene. NOS2 protein was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5462baff82f9e8f122edd77be46d189
https://pubmed.ncbi.nlm.nih.gov/16329147
https://pubmed.ncbi.nlm.nih.gov/16329147
Autor:
Hagit F. Yerushalmi, David G. Besselsen, Natalia A. Ignatenko, Karen A. Blohm‐Mangone, Jose L. Padilla‐Torres, David E. Stringer, Haiyan Cui, Hana Holubec, Claire M. Payne, Eugene W. Gerner
Publikováno v:
Molecular Carcinogenesis; Feb2006, Vol. 45 Issue 2, p93-105, 13p