Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jose L. McFaline"'
Autor:
Lauren M Saunders, Abhishek K Mishra, Andrew J Aman, Victor M Lewis, Matthew B Toomey, Jonathan S Packer, Xiaojie Qiu, Jose L McFaline-Figueroa, Joseph C Corbo, Cole Trapnell, David M Parichy
Publikováno v:
eLife, Vol 8 (2019)
Thyroid hormone (TH) regulates diverse developmental events and can drive disparate cellular outcomes. In zebrafish, TH has opposite effects on neural crest derived pigment cells of the adult stripe pattern, limiting melanophore population expansion,
Externí odkaz:
https://doaj.org/article/d802aca4e8474f9799616ec7022d2e47
Autor:
Mohammad Lotfollahi, Anna Klimovskaia Susmelj, Carlo De Donno, Leon Hetzel, Yuge Ji, Ignacio L Ibarra, Sanjay R Srivatsan, Mohsen Naghipourfar, Riza M Daza, Beth Martin, Jay Shendure, Jose L McFaline‐Figueroa, Pierre Boyeau, F Alexander Wolf, Nafissa Yakubova, Stephan Günnemann, Cole Trapnell, David Lopez‐Paz, Fabian J Theis
Publikováno v:
Molecular Systems Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9778b6700f04cdd8cc39404b8e1c5c51
https://doi.org/10.15252/msb.202211517
https://doi.org/10.15252/msb.202211517
Autor:
Juan Jesus Vicente, Kainat Khan, Grant Tillinghast, José L. McFaline-Figueroa, Yasemin Sancak, Nephi Stella
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Microtubule targeting agents (MTAs) are commonly prescribed to treat cancers and predominantly kill cancer cells in mitosis. Significantly, some MTA-treated cancer cells escape death in mitosis, exit mitosis and become malignant polyploid gi
Externí odkaz:
https://doaj.org/article/deafb19afc12476097f2997a23be0b83
Autor:
Gregory T. Booth, Riza M. Daza, Sanjay R. Srivatsan, José L. McFaline-Figueroa, Rula Green Gladden, Andrew C. Mullen, Scott N. Furlan, Jay Shendure, Cole Trapnell
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-23 (2023)
Abstract Single-cell chromatin accessibility has emerged as a powerful means of understanding the epigenetic landscape of diverse tissues and cell types, but profiling cells from many independent specimens is challenging and costly. Here we describe
Externí odkaz:
https://doaj.org/article/11167b29a9ec4b1fa5f656373a3275ff
Autor:
Jacquelyn C. Yanch, Aline M. Thomas, Joel S. Greenberger, Werner Olipitz, Peter C. Dedon, James T. Mutamba, Leona D. Samson, Bevin P. Engelward, Bo Pang, Pallavi Lonkar, Jose L. McFaline, Dominika M. Wiktor-Brown, Joe Shuga
Publikováno v:
Environmental Health Perspectives. 120:1130-1136
Background: In the event of a nuclear accident, people are exposed to elevated levels of continuous low dose-rate radiation. Nevertheless, most of the literature describes the biological effects of acute radiation. Objectives: DNA damage and mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::895b28d82a2e8d00aeaee4bdf5b5f544
https://doi.org/10.1289/ehp.1104294
https://doi.org/10.1289/ehp.1104294
Autor:
A. L. Doernte, Michelle V. Williams, Steven R. Tannenbaum, James G. Fox, Arlin B. Rogers, Steven A. Weinman, Yan Feng, Arkadiusz R. Raczynski, Stanley M. Lemon, Jose L. McFaline, Rebecca C. Fry, Jeannette Louise Allen Fiala, Elizabeth J. Theve, Peter C. Dedon, John M. Essigmann, David B. Schauer
Publikováno v:
Gut. 59:88-97
Background and aims: Hepatocellular carcinoma (HCC) frequently results from synergism between chemical and infectious liver carcinogens. Worldwide, the highest incidence of HCC is in regions endemic for the foodborne contaminant aflatoxin B1 (AFB1) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40718358e8f3f9dc29b047c344a0d43f
https://doi.org/10.1136/gut.2009.183749
https://doi.org/10.1136/gut.2009.183749
Autor:
Jose L. McFaline, Elaine F. Plummer, Bo Pang, Koli Taghizadeh, Matthew B. Sullivan, Peter C. Dedon, Min Dong
Publikováno v:
Nature Protocols. 3:1287-1298
The analysis of damage products as biomarkers of inflammation has been hampered by a poor understanding of the chemical biology of inflammation, the lack of sensitive analytical methods and a focus on single chemicals as surrogates for inflammation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad55b5649722dfc019b7f1418e16e5a
https://doi.org/10.1038/nprot.2008.119
https://doi.org/10.1038/nprot.2008.119
Autor:
Erin G. Prestwich, Jose L. McFaline, Peter C. Dedon, C. Eric Elmquist, Bo Pang, Michael S. DeMott
Publikováno v:
Biomarkers in Medicine. 1:293-312
Inflammation is now a proven cause of human diseases such as cancer and cardiovascular disease. One potential link between inflammation and disease involves secretion of reactive chemical species by immune cells, with chronic damage to host epithelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1602debfb5c1c11164ad37649567ded
https://doi.org/10.2217/17520363.1.2.293
https://doi.org/10.2217/17520363.1.2.293
Autor:
Hyeon-Jin Kim, Greg Booth, Lauren Saunders, Sanjay Srivatsan, José L. McFaline-Figueroa, Cole Trapnell
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Using spike-in controls with current single cell RNA-seq platforms remains a challenge. Here, the authors use a mixture of short, unmodified DNA oligos as a normalization standard for sci-RNAseq to improve the detection of global transcriptome change
Externí odkaz:
https://doaj.org/article/a04ceeedb7434c489f81dc97698f4e17
Autor:
Bo Pang, Pallavi Lonkar, Laura J. Trudel, Erin G. Prestwich, Aswin Mangerich, Peter C. Dedon, Jose L. McFaline, Matthew R. Sullivan, Koli Taghizedeh
One possible mechanism linking inflammation with cancer involves the generation of reactive oxygen, nitrogen, and halogen species by activated macrophages and neutrophils infiltrating sites of infection or tissue damage, with these chemical mediators
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd356a389a3836af0bf18f20bad7fef
https://europepmc.org/articles/PMC3726579/
https://europepmc.org/articles/PMC3726579/
