Neuropilins as potential biomarkers in hepatocellular carcinoma: a systematic review of basic and clinical implications

Autor: Paula Fernández-Palanca, Tania Payo-Serafín, Carolina Méndez-Blanco, Beatriz San-Miguel, María J. Tuñón, Javier González-Gallego, José L. Mauriz

Publikováno v: Clinical and Molecular Hepatology, Vol 29, Iss 2, Pp 293-319 (2023)

Hepatocellular carcinoma (HCC) is one of the most common and deadly cancers worldwide and is characterized by complex molecular carcinogenesis. Neuropilins (NRPs) NRP1 and NRP2 are the receptors of multiple proteins involved in key signaling pathways

Externí odkaz: https://doaj.org/article/9a5efbf8caa44fb88a192770aa93373f

Effects of quercetin on polychlorinated biphenyls-induced liver injury in rats

Autor: Cléia Rocha de Oliveira, Juliana Ceolin, Renata Rocha de Oliveira, Elizângela Gonçalves Schemitt, Josieli Raskopf Colares, Liliane de Freitas Bauermann, Ijoni Hilda Costabeber, Maria Isabel Morgan-Martins, Jose L Mauriz, Juliana da Silva, Juliana Moysés Reyes, Norma Possa Marroni

Publikováno v: Redalyc
Nutrición Hospitalaria v.29 n.5 2014
SciELO España. Revistas Científicas Españolas de Ciencias de la Salud
instname
Nutrición Hospitalaria, Vol 29, Iss 5, Pp 1141-1148 (2014)

Polychlorinated biphenyls (PCBs), used as pesticides in agriculture, can lead to irreversible injuries in living organisms, particularly in liver. Oxidative stress has been implicated in the liver pathogenesis induced by different molecules, includin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d5bd99e413189f44820eac141649852f
https://pubmed.ncbi.nlm.nih.gov/24951996

Impact of Aberrant β-Catenin Pathway on Cholangiocarcinoma Heterogeneity

Autor: Elisa Lozano, Paula Sanchon-Sanchez, Ana Morente-Carrasco, Luis Miguel Chinchilla-Tábora, José L. Mauriz, Paula Fernández-Palanca, Jose J. G. Marin, Rocio I. R. Macias

Publikováno v: Cells, Vol 12, Iss 8, p 1141 (2023)

The poor prognosis of most cases of advanced cholangiocarcinoma (CCA) constitutes a severe problem in modern oncology, which is aggravated by the fact that the incidence of this liver cancer is increasing worldwide and is often diagnosed late, when s

Externí odkaz: https://doaj.org/article/9f182bce6ddd42beb4318addaf638faf

Sorafenib resistance in hepatocarcinoma: role of hypoxia-inducible factors

Autor: Carolina Méndez-Blanco, Flavia Fondevila, Andrés García-Palomo, Javier González-Gallego, José L. Mauriz

Publikováno v: Experimental and Molecular Medicine, Vol 50, Iss 10, Pp 1-9 (2018)

Liver cancer: overcoming treatment resistance Targeting hypoxia-inducible factors (HIFs), regulatory proteins induced by low oxygen levels, could increase the effectiveness of sorafenib, the only systemic therapy approved for advanced liver cancer. L

Externí odkaz: https://doaj.org/article/141a6fd1ea72407e969587ff2a31ec12

Glutamine prevents gastric oxidative stress in an animal model of portal hypertension gastropathy(◆)(◆)This work was supported by grants from the Conselho Nacional de Desenvolvimiento Científico e Tecnológico (CNPq), Fundaçáo de Amparo a Pesquisa do Rio Grande do Sul (FAPERGS), and Fundo de Incentivo á Pesquisa e Eventos (FIPE) do Hospital de Clínicas de Porto Alegre (HCPA). CIBEREHD is funded by the Instituto de Salud Carlos III.

Autor: Camila Marques, José L. Mauriz, Douglas Simonetto, Claudio A. Marroni, María J. Tuñon, Javier González-Gallego, Norma P. Marroni

Publikováno v: Annals of Hepatology, Vol 10, Iss 4, Pp 531-539 (2011)

Background and rationale. Portal hypertension (PHI) is a clinical syndrome characterized by increases of the blood flow and/or of the vascular resistance in the portal system. A direct consequence of PHI can appearance different lesions on the gastri

Externí odkaz: https://doaj.org/article/09e02aebd7414475ab11fc2e0eb8a90b