Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Jose L. Labandeira‐Garcia"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Angiotensin, through its type-1 receptor (AT1), is a major inducer of inflammation and oxidative stress, contributing to several diseases. Autoimmune processes have been involved in neurodegeneration, including Parkinson’s disease (PD). AT1 autoant
Externí odkaz:
https://doaj.org/article/b9174b65f336436d930e97de2471f8c7
Autor:
Lucia Lage, Ana I. Rodriguez-Perez, Begoña Villar-Cheda, Jose L. Labandeira-Garcia, Antonio Dominguez-Meijide
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-20 (2024)
Abstract The brain renin-angiotensin system (RAS) has been related to dopaminergic degeneration, and high expression of the angiotensin II (AngII) type 1 receptor (AT1) gene is a marker of the most vulnerable neurons in humans. However, it is unknown
Externí odkaz:
https://doaj.org/article/840cafb5aecd4c9f93c5a414836891d4
Autor:
Carmen M. Labandeira, Maria A. Pedrosa, Aloia Quijano, Rita Valenzuela, Pablo Garrido-Gil, Mariña Sanchez-Andrade, Juan A. Suarez-Quintanilla, Ana I. Rodriguez-Perez, Jose L. Labandeira-Garcia
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract The role of autoimmunity in neurodegeneration has been increasingly suggested. The renin-angiotensin system (RAS) autoantibodies play a major role in several peripheral inflammatory processes. Dysregulation of brain RAS has been involved in
Externí odkaz:
https://doaj.org/article/f83718c455114c328bfe7464be77c6e6
Autor:
Rita Valenzuela, Ana I. Rodriguez-Perez, Maria A. Costa-Besada, Rafael Rivas-Santisteban, Pablo Garrido-Gil, Andrea Lopez-Lopez, Gemma Navarro, Jose L. Lanciego, Rafael Franco, Jose L. Labandeira-Garcia
Publikováno v:
Redox Biology, Vol 46, Iss , Pp 102078- (2021)
ACE2 plays a pivotal role in the balance between the pro-oxidative pro-inflammatory and the anti-oxidative anti-inflammatory arms of the renin-angiotensin system. Furthermore, ACE2 is the entry receptor for SARS-CoV-2. Clarification of ACE2-related m
Externí odkaz:
https://doaj.org/article/23210ef8205949708f8f783e72da2298
Autor:
Rita Valenzuela, Maria A. Pedrosa, Pablo Garrido‐Gil, Carmen M. Labandeira, Gemma Navarro, Rafael Franco, Ana I. Rodriguez‐Perez, Jose L. Labandeira‐Garcia
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 4, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/87a7219b3f1b410fa07ff8b482feed7c
Publikováno v:
Frontiers in Neuroanatomy, Vol 14 (2020)
Parkinson’s disease (PD) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra. However, other non-dopaminergic neuronal systems such as the serotonergic system are also involved. Serotonergic dysfunction is assoc
Externí odkaz:
https://doaj.org/article/a017b6fad7ea442c958b50577bbbde42
Autor:
Aloia Quijano, Carmen Diaz-Ruiz, Andrea Lopez-Lopez, Begoña Villar-Cheda, Ana Muñoz, Ana I. Rodriguez-Perez, Jose L. Labandeira-Garcia
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 329 (2022)
The tissue renin–angiotensin system (RAS) has been shown to be involved in prooxidative and proinflammatory changes observed in aging and aging-related diseases such as dopaminergic degeneration in Parkinson’s disease (PD). We studied the activat
Externí odkaz:
https://doaj.org/article/bba0dc916a3b430fa3412779f6a057a2
Autor:
Jose L. Labandeira-Garcia, Carmen M. Labandeira, Rita Valenzuela, Maria A. Pedrosa, Aloia Quijano, Ana I. Rodriguez-Perez
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 502 (2022)
A massive worldwide vaccination campaign constitutes the main tool against the COVID-19 pandemic. However, drug treatments are also necessary. Antivirals are the most frequently considered treatments. However, strategies targeting mechanisms involved
Externí odkaz:
https://doaj.org/article/882c9fa6fefe4cc5ab75ada407a83f15
Autor:
Juan A. Parga, Ana I. Rodriguez-Perez, Maria Garcia-Garrote, Jannette Rodriguez-Pallares, Jose L. Labandeira-Garcia
Publikováno v:
Data in Brief, Vol 21, Iss , Pp 934-942 (2018)
This article describes the effect of the oxidative stress inducers Angiotensin II and 6-hydroxydopamine (6-OHDA) on different cell lines. The levels of expression Angiotensin type 1 and type 2 receptors in different dopaminergic cell lines are shown.
Externí odkaz:
https://doaj.org/article/d48a73624b66434386d22aa635389728
Autor:
Juan A. Parga, Ana I. Rodriguez-Perez, Maria Garcia-Garrote, Jannette Rodriguez-Pallares, Jose L. Labandeira-Garcia
Publikováno v:
Antioxidants, Vol 10, Iss 11, p 1649 (2021)
Reactive oxygen species (ROS) are signalling molecules used to regulate cellular metabolism and homeostasis. However, excessive ROS production causes oxidative stress, one of the main mechanisms associated with the origin and progression of neurodege
Externí odkaz:
https://doaj.org/article/463e6b227e944cbeaef996be550f6b50