Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Jose L. Garcia-Perez"'
Autor:
Manvendra Singh, Aleksandra M. Kondrashkina, Thomas J. Widmann, Jose L. Cortes, Vikas Bansal, Jichang Wang, Christine Römer, Marta Garcia-Canadas, Jose L. Garcia-Perez, Laurence D. Hurst, Zsuzsanna Izsvák
Publikováno v:
PLoS Biology, Vol 21, Iss 6 (2023)
There remains much that we do not understand about the earliest stages of human development. On a gross level, there is evidence for apoptosis, but the nature of the affected cell types is unknown. Perhaps most importantly, the inner cell mass (ICM),
Externí odkaz:
https://doaj.org/article/c79ae257f97a464eb8488ff58e3fdc6f
Autor:
Martin J. Blythe, Ayhan Kocer, Alejandro Rubio-Roldan, Tom Giles, Abdulkadir Abakir, Côme Ialy-Radio, Lee M. Wheldon, Oxana Bereshchenko, Stefano Bruscoli, Alexander Kondrashov, Joël R. Drevet, Richard D. Emes, Andrew D. Johnson, John R. McCarrey, Daniel Gackowski, Ryszard Olinski, Julie Cocquet, Jose L. Garcia-Perez, Alexey Ruzov
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Blythe et al investigate the patterns of oxidized forms of the 5-methylcytosine DNA modification during spermatogenesis. They find that open reading frames of evolutionarily young and transcriptionally active LINE-1 retrotransposons are enriched in 5
Externí odkaz:
https://doaj.org/article/404f4300a2c74fb1b5b1fc739c852701
Autor:
Sabine Klawitter, Nina V. Fuchs, Kyle R. Upton, Martin Muñoz-Lopez, Ruchi Shukla, Jichang Wang, Marta Garcia-Cañadas, Cesar Lopez-Ruiz, Daniel J. Gerhardt, Attila Sebe, Ivana Grabundzija, Sylvia Merkert, Patricia Gerdes, J. Andres Pulgarin, Anja Bock, Ulrike Held, Anett Witthuhn, Alexandra Haase, Balázs Sarkadi, Johannes Löwer, Ernst J. Wolvetang, Ulrich Martin, Zoltán Ivics, Zsuzsanna Izsvák, Jose L. Garcia-Perez, Geoffrey J. Faulkner, Gerald G. Schumann
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Genetic and epigenetic abnormalities have been found to result from reprogramming of differentiated cells into human induced pluripotent stem cells (hiPSCs). Here, Klawitter et al.identify endogenous L1, Alu and SVA mobilization during reprogramming,
Externí odkaz:
https://doaj.org/article/c3ef18eb5c21445d985ad18b9ff23d87
Autor:
Sabine Klawitter, Nina V. Fuchs, Kyle R. Upton, Martin Muñoz-Lopez, Ruchi Shukla, Jichang Wang, Marta Garcia-Cañadas, Cesar Lopez-Ruiz, Daniel J. Gerhardt, Attila Sebe, Ivana Grabundzija, Sylvia Merkert, Patricia Gerdes, J. Andres Pulgarin, Anja Bock, Ulrike Held, Anett Witthuhn, Alexandra Haase, Balázs Sarkadi, Johannes Löwer, Ernst J. Wolvetang, Ulrich Martin, Zoltán Ivics, Zsuzsanna Izsvák, Jose L. Garcia-Perez, Geoffrey J. Faulkner, Gerald G. Schumann
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
This Article contains an error in the author affiliations. The correct affiliation for author Ruchi Shukla is ‘MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road, Edinburgh, EH4 2XU, UK’, an
Externí odkaz:
https://doaj.org/article/73f8a71f8e3443d1af99aa1de2e348c3
Autor:
Marta Garcia-Cañadas, Francisco J. Sanchez-Luque, Laura Sanchez, Johana Rojas, Jose L. Garcia Perez
Publikováno v:
Transposable Elements ISBN: 9781071628829
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c31167062ac70bf8f5c613a5760fd9f3
https://doi.org/10.1007/978-1-0716-2883-6_13
https://doi.org/10.1007/978-1-0716-2883-6_13
Autor:
Marta, Garcia-Cañadas, Francisco J, Sanchez-Luque, Laura, Sanchez, Johana, Rojas, Jose L, Garcia Perez
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2607
The ongoing mobilization of active non-long terminal repeat (LTR) retrotransposons continues to impact the genomes of most mammals, including humans and rodents. Non-LTR retrotransposons mobilize using an intermediary RNA and a copy-and-paste mechani
Autor:
Victor Billon, Francisco J. Sanchez-Luque, Jay Rasmussen, Gabriela O. Bodea, Daniel J. Gerhardt, Patricia Gerdes, Seth W. Cheetham, Stephanie N. Schauer, Prabha Ajjikuttira, Thomas J. Meyer, Cora E. Layman, Kimberly A. Nevonen, Natasha Jansz, Jose L. Garcia-Perez, Sandra R. Richardson, Adam D. Ewing, Lucia Carbone, Geoffrey J. Faulkner
Publikováno v:
Genome research. 32(7)
The retrotransposon LINE-1 (L1) is central to the recent evolutionary history of the human genome and continues to drive genetic diversity and germline pathogenesis. However, the spatiotemporal extent and biological significance of somatic L1 activit
Autor:
Jose L. Garcia-Perez, Côme Ialy-Radio, Alejandro Rubio-Roldan, Julie Cocquet, Oxana Bereshchenko, Joël R. Drevet, Stefano Bruscoli, Ryszard Olinski, Alexey Ruzov, Daniel Gackowski, Abdulkadir Abakir, Tom C. Giles, Richard D. Emes, Martin J. Blythe, Alexander Kondrashov, Andrew D. Johnson, John R. McCarrey, Ayhan Kocer, Lee M. Wheldon
Publikováno v:
Communications Biology
Communications Biology, 2021, 4, pp.691. ⟨10.1038/s42003-021-02217-8⟩
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Communications Biology, 2021, 4, pp.691. ⟨10.1038/s42003-021-02217-8⟩
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Chromatin of male and female gametes undergoes a number of reprogramming events during the transition from germ cell to embryonic developmental programs. Although the rearrangement of DNA methylation patterns occurring in the zygote has been extensiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6a12ff311170c5847fa1e587d0812c
https://hal.science/hal-03670149
https://hal.science/hal-03670149
Autor:
Jennifer Doig, Hélio van der Linden, Ram Kumar, Waad Albawardi, Mathieu P Rodero, Caroline A Salmon, Angus Dobbie, Hilde Van Esch, Marie Vermelle, Cristina Cereda, Nick Gilbert, Marine Depp, Andrew P. Jackson, Kevin Rostasy, Robert Olaso, Jean-François Deleuze, Luis Seabra, Frances Elmslie, Davide Tonduti, Diane Doummar, Somdutta Dhir, Duncan Sproul, Alice Lepelley, John H. Livingston, Kate Webb, Yanick J. Crow, Alejandro Rubio-Roldan, Marie-Louise Frémond, Christiaan Scott, Simona Orcesi, Ashish Dhir, Sylviane Peudenier, Guy Touati, Anirban Majumdar, Kate Lamb, Jose L. Garcia-Perez, Vanessa Cavallera, Liesbeth De Waele, Maria José Martin-Niclos, Julien Baruteau, Marie-Thérèse El-Daher, Jonny Hertzog, Jonathan Buckley, Martin A M Reijns, Charles Marques Lorenço, Erika Della Mina, Marialuisa Valente, Karine Brochard, Anne Boland-Auge, Andrew P. Badrock, Ann P. Wheeler, Natalie F. Blair, Carolina Uggenti, Gillian I. Rice, Margarete Koch-Hogrebe, Jan Rehwinkel
Publikováno v:
Uggenti, C, Lepelley, A, Depp, M, Badrock, A P, Rodero, M P, El-Daher, M-T, Rice, G I, Dhir, S, Wheeler, A P, Dhir, A, Albawardi, W, Fremond, M-L, Seabra, L, Doig, J, Blair, N, Martin-Niclos, M J, Della Mina, E, Rubio-Roldan, A, Garcia-Perez, J L, Sproul, D, Rehwinkel, J, Hertzog, J, Boland-Auge, A, Olaso, R, Deleuze, J-F, Baruteau, J, Brochard, K, Buckley, J, Cavallera, V, Cereda, C, De Waele, L M H, Dobbie, A, Doummar, D, Elmslie, F, Koch-Hogrebe, M, Kumar, R, Lamb, K, Livingston, J H, Majumdar, A, Lorenco, C M, Orcesi, S, Peudenier, S, Rostasy, K, Salmon, C A, Scott, C, Tonduti, D, Touati, G, Valente, M, van der Linden, H J, Van Esch, H, Vermelle, M, Webb, K, Jackson, A P, Reijns, M A M, Gilbert, N & Crow, Y J 2020, ' cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing ', Nature Genetics, vol. 52, no. 12, pp. 1364-1372 . https://doi.org/10.1038/s41588-020-00737-3
Nature Genetics
Nature Genetics, 2020, 52 (12), pp.1364-1372. ⟨10.1038/s41588-020-00737-3⟩
Nature Genetics, Nature Publishing Group, 2020, 52 (12), pp.1364-1372. ⟨10.1038/s41588-020-00737-3⟩
Uggenti, C, Lepelley, A, Depp, M, Badrock, A P, Rodero, M P, El-Daher, M-T, Rice, G I, Dhir, S, Wheeler, A P, Dhir, A, Albawardi, W, Frémond, M-L, Seabra, L, Doig, J, Blair, N, Martin-Niclos, M J, Della Mina, E, Rubio-Roldán, A, García-Pérez, J L, Sproul, D, Rehwinkel, J, Hertzog, J, Boland-Auge, A, Olaso, R, Deleuze, J, Baruteau, J, Brochard, K, Buckley, J, Cavallera, V, Cereda, C, De Waele, L M H, Dobbie, A, Doummar, D, Elmslie, F, Koch-Hogrebe, M, Kumar, R, Lamb, K, Livingston, J H, Majumdar, A, Lorenço, C M, Orcesi, S, Peudenier, S, Rostasy, K, Salmon, C A, Scott, C, Tonduti, D, Touati, G, Valente, M, Van Der Linden Jr, H, Van Esch, H, Vermelle, M, Webb, K, Jackson, A P, Reijns, M A M, Gilbert, N & Crow, Y J 2020, ' cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing ', Nature Genetics, vol. 52, no. 12, pp. 1364-1372 . https://doi.org/10.1038/s41588-020-00737-3
Nature Genetics
Nature Genetics, 2020, 52 (12), pp.1364-1372. ⟨10.1038/s41588-020-00737-3⟩
Nature Genetics, Nature Publishing Group, 2020, 52 (12), pp.1364-1372. ⟨10.1038/s41588-020-00737-3⟩
Uggenti, C, Lepelley, A, Depp, M, Badrock, A P, Rodero, M P, El-Daher, M-T, Rice, G I, Dhir, S, Wheeler, A P, Dhir, A, Albawardi, W, Frémond, M-L, Seabra, L, Doig, J, Blair, N, Martin-Niclos, M J, Della Mina, E, Rubio-Roldán, A, García-Pérez, J L, Sproul, D, Rehwinkel, J, Hertzog, J, Boland-Auge, A, Olaso, R, Deleuze, J, Baruteau, J, Brochard, K, Buckley, J, Cavallera, V, Cereda, C, De Waele, L M H, Dobbie, A, Doummar, D, Elmslie, F, Koch-Hogrebe, M, Kumar, R, Lamb, K, Livingston, J H, Majumdar, A, Lorenço, C M, Orcesi, S, Peudenier, S, Rostasy, K, Salmon, C A, Scott, C, Tonduti, D, Touati, G, Valente, M, Van Der Linden Jr, H, Van Esch, H, Vermelle, M, Webb, K, Jackson, A P, Reijns, M A M, Gilbert, N & Crow, Y J 2020, ' cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing ', Nature Genetics, vol. 52, no. 12, pp. 1364-1372 . https://doi.org/10.1038/s41588-020-00737-3
International audience; Inappropriate stimulation or defective negative regulation of the type I interferon response can lead to autoinflammation. In genetically uncharacterized cases of the type I interferonopathy Aicardi-Goutières syndrome, we ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ff60c1ad94564d27eaeaacc887a26e2
https://www.research.manchester.ac.uk/portal/en/publications/cgasmediated-induction-of-type-i-interferon-due-to-inborn-errors-of-histone-premrna-processing(2af4767a-21e6-4a78-93d2-f68838fee8a8).html
https://www.research.manchester.ac.uk/portal/en/publications/cgasmediated-induction-of-type-i-interferon-due-to-inborn-errors-of-histone-premrna-processing(2af4767a-21e6-4a78-93d2-f68838fee8a8).html